Christopher Vincent Carman
Other Academic

Christopher Vincent Carman

Research Associate

Environmental Health


Overview

Major Research Interests: Adaptive & Innate Immune Cell Regulation and Trafficking

Specialties: Immunology, Inflammation, Vascular Biology, Immunomodulation, Bioengineering, Targeted Therapies

Our laboratory investigates the basic molecular and cell biological underpinnings of vascular inflammation and peripheral regulation of immune responses with special emphasis on leukocyte-endothelial interactions. Our studies also implement extensive molecular and cellular engineering approaches toward development of new immuno-modulation strategies for use in inflammatory, autoimmune, allogeneic and cancerous diseases.

Recently our studies have further focused on micro-environmental regulation of immunity and development of bioengineering approaches (e.g., in vitro chip, organoid and hypoxia technologies) as innovative platforms for studying tumor biology/immunology and for facilitating drug development.

Specific Topics we are currently investigating include:

The regulation of immune cell activation and migration
Peripheral regulation of adaptive and innate immune responses
Immuno-modulation of transplantation, autoimmunity and cancer
The cytoskeletal and biomechanical regulation of vascular integrity


Bibliography