Author Correction: The effects of mutational processes and selection on driver mutations across cancer types.
Temko D, Tomlinson IPM, Severini S, Schuster-Böckler B, Graham TA.
Nat Commun. 2020 04 20. 11(1):1959. PMID: 32313050
Other Positions
Post Doc, Visiting (Stip)
Stem Cell and Regenerative Biology -Other
Harvard Faculty of Arts and Sciences
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Measuring single cell divisions in human tissues from multi-region sequencing data.
Werner B, Case J, Williams MJ, Chkhaidze K, Temko D, Fernández-Mateos J, Cresswell GD, Nichol D, Cross W, Spiteri I, Huang W, Tomlinson IPM, Barnes CP, Graham TA, Sottoriva A.
Nat Commun. 2020 02 25. 11(1):1035. PMID: 32098957
The evolutionary landscape of colorectal tumorigenesis.
Cross W, Kovac M, Mustonen V, Temko D, Davis H, Baker AM, Biswas S, Arnold R, Chegwidden L, Gatenbee C, Anderson AR, Koelzer VH, Martinez P, Jiang X, Domingo E, Woodcock DJ, Feng Y, Kovacova M, Maughan T, Jansen M, Rodriguez-Justo M, Ashraf S, Guy R, Cunningham C, East JE, Wedge DC, Wang LM, Palles C, Heinimann K, Sottoriva A, Leedham SJ, Graham TA, Tomlinson IPM.
Nat Ecol Evol. 2018 10. 2(10):1661-1672. PMID: 30177804
Evolutionary history of human colitis-associated colorectal cancer.
Baker AM, Cross W, Curtius K, Al Bakir I, Choi CR, Davis HL, Temko D, Biswas S, Martinez P, Williams MJ, Lindsay JO, Feakins R, Vega R, Hayes SJ, Tomlinson IPM, McDonald SAC, Moorghen M, Silver A, East JE, Wright NA, Wang LM, Rodriguez-Justo M, Jansen M, Hart AL, Leedham SJ, Graham TA.
Gut. 2019 06. 68(6):985-995. PMID: 29991641
The effects of mutational processes and selection on driver mutations across cancer types.
Temko D, Tomlinson IPM, Severini S, Schuster-Böckler B, Graham TA.
Nat Commun. 2018 05 10. 9(1):1857. PMID: 29748584
Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.
Temko D, Van Gool IC, Rayner E, Glaire M, Makino S, Brown M, Chegwidden L, Palles C, Depreeuw J, Beggs A, Stathopoulou C, Mason J, Baker AM, Williams M, Cerundolo V, Rei M, Taylor JC, Schuh A, Ahmed A, Amant F, Lambrechts D, Smit VT, Bosse T, Graham TA, Church DN, Tomlinson I.
J Pathol. 2018 07. 245(3):283-296. PMID: 29604063
Mathematical Modeling Links Pregnancy-Associated Changes and Breast Cancer Risk.
Temko D, Cheng YK, Polyak K, Michor F.
Cancer Res. 2017 06 01. 77(11):2800-2809. PMID: 28360138