Huwenbo Shi

A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic aetiology with obesity.

Zhu Z, Li J, Si J, Ma B, Shi H, Lv J, Cao W, Guo Y, Millwood IY, Walters RG, Lin K, Yang L, Chen Y, Du H, Yu B, Hasegawa K, Camargo CA, Moffatt MF, Cookson WOC, Chen J, Chen Z, Li L, Yu C, Liang L.

Eur Respir J. 2021 Oct. 58(4). PMID: 33766948

Population-specific causal disease effect sizes in functionally important regions impacted by selection.

Shi H, Gazal S, Kanai M, Koch EM, Schoech AP, Siewert KM, Kim SS, Luo Y, Amariuta T, Huang H, Okada Y, Raychaudhuri S, Sunyaev SR, Price AL.

Nat Commun. 2021 02 17. 12(1):1098. PMID: 33597505

PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statistics.

Lee CH, Shi H, Pasaniuc B, Eskin E, Han B.

Am J Hum Genet. 2021 01 07. 108(1):36-48. PMID: 33352115

Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data.

Shi H, Burch KS, Johnson R, Freund MK, Kichaev G, Mancuso N, Manuel AM, Dong N, Pasaniuc B.

Am J Hum Genet. 2020 06 04. 106(6):805-817. PMID: 32442408

Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

Zhu Z, Zhu X, Liu CL, Shi H, Shen S, Yang Y, Hasegawa K, Camargo CA, Liang L.

Eur Respir J. 2019 12. 54(6). PMID: 31619474

RAISS: robust and accurate imputation from summary statistics.

Julienne H, Shi H, Pasaniuc B, Aschard H.

Bioinformatics. 2019 11 01. 35(22):4837-4839. PMID: 31173064

Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank.

Zhu Z, Guo Y, Shi H, Liu CL, Panganiban RA, Chung W, O'Connor LJ, Himes BE, Gazal S, Hasegawa K, Camargo CA, Qi L, Moffatt MF, Hu FB, Lu Q, Cookson WOC, Liang L.

J Allergy Clin Immunol. 2020 02. 145(2):537-549. PMID: 31669095

Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture.

Hou K, Burch KS, Majumdar A, Shi H, Mancuso N, Wu Y, Sankararaman S, Pasaniuc B.

Nat Genet. 2019 08. 51(8):1244-1251. PMID: 31358995

Probabilistic fine-mapping of transcriptome-wide association studies.

Mancuso N, Freund MK, Johnson R, Shi H, Kichaev G, Gusev A, Pasaniuc B.

Nat Genet. 2019 04. 51(4):675-682. PMID: 30926970

Phenotype-Specific Enrichment of Mendelian Disorder Genes near GWAS Regions across 62 Complex Traits.

Freund MK, Burch KS, Shi H, Mancuso N, Kichaev G, Garske KM, Pan DZ, Miao Z, Mohlke KL, Laakso M, Pajukanta P, Pasaniuc B, Arboleda VA.

Am J Hum Genet. 2018 10 04. 103(4):535-552. PMID: 30290150