Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane.
Kim S, Chung J, Arlt H, Pak AJ, Farese RV, Walther TC, Voth GA.
Elife. 2022 05 18. 11. PMID: 35583926
Other Positions
Associate of the Department of Molecular and Cellular Biology
Molecular and Cellular Biology -Other Academic
Harvard Faculty of Arts and Sciences
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Bibliography
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Nature. 2021 Nov. 599(7885):E5. PMID: 34732896
An open-access volume electron microscopy atlas of whole cells and tissues.
Xu CS, Pang S, Shtengel G, Müller A, Ritter AT, Hoffman HK, Takemura SY, Lu Z, Pasolli HA, Iyer N, Chung J, Bennett D, Weigel AV, Freeman M, van Engelenburg SB, Walther TC, Farese RV, Lippincott-Schwartz J, Mellman I, Solimena M, Hess HF.
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Nanoscale subcellular architecture revealed by multicolor three-dimensional salvaged fluorescence imaging.
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LDAF1 and Seipin Form a Lipid Droplet Assembly Complex.
Chung J, Wu X, Lambert TJ, Lai ZW, Walther TC, Farese RV.
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PtdIns4P synthesis by PI4KIIIa at the plasma membrane and its impact on plasma membrane identity.
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Nuclear import of hTERT requires a bipartite nuclear localization signal and Akt-mediated phosphorylation.
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