Jennifer Mitchel

In well-differentiated primary human bronchial epithelial cells, TGF-ß1 and TGF-ß2 induce expression of furin.

O'Sullivan MJ, Mitchel JA, Mwase C, McGill M, Kanki P, Park JA.

Am J Physiol Lung Cell Mol Physiol. 2021 02 01. 320(2):L246-L253. PMID: 33174447

Epithelial layer unjamming shifts energy metabolism toward glycolysis.

DeCamp SJ, Tsuda VMK, Ferruzzi J, Koehler SA, Giblin JT, Roblyer D, Zaman MH, Weiss ST, Kiliç A, De Marzio M, Park CY, Ogassavara NC, Mitchel JA, Butler JP, Fredberg JJ.

Sci Rep. 2020 10 27. 10(1):18302. PMID: 33110128

In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition.

Mitchel JA, Das A, O'Sullivan MJ, Stancil IT, DeCamp SJ, Koehler S, Ocaña OH, Butler JP, Fredberg JJ, Nieto MA, Bi D, Park JA.

Nat Commun. 2020 10 07. 11(1):5053. PMID: 33028821

Airway mechanical compression: its role in asthma pathogenesis and progression.

Veerati PC, Mitchel JA, Reid AT, Knight DA, Bartlett NW, Park JA, Grainge CL.

Eur Respir Rev. 2020 Sep 30. 29(157). PMID: 32759373

Irradiation Induces Epithelial Cell Unjamming.

O'Sullivan MJ, Mitchel JA, Das A, Koehler S, Levine H, Bi D, Nagel ZD, Park JA.

Front Cell Dev Biol. 2020. 8:21. PMID: 32117962

Mechanical forces induce an asthma gene signature in healthy airway epithelial cells.

Kiliç A, Ameli A, Park JA, Kho AT, Tantisira K, Santolini M, Cheng F, Mitchel JA, McGill M, O'Sullivan MJ, De Marzio M, Sharma A, Randell SH, Drazen JM, Fredberg JJ, Weiss ST.

Sci Rep. 2020 01 22. 10(1):966. PMID: 31969610

Unjamming and collective migration in MCF10A breast cancer cell lines.

Kim JH, Pegoraro AF, Das A, Koehler SA, Ujwary SA, Lan B, Mitchel JA, Atia L, He S, Wang K, Bi D, Zaman MH, Park JA, Butler JP, Lee KH, Starr JR, Fredberg JJ.

Biochem Biophys Res Commun. 2020 01 15. 521(3):706-715. PMID: 31699371

Increased extracellular maspin levels after mechanical compression in vitro or allergen challenge in vivo.

Kim SH, Mitchel JA, McGill M, Cremona TP, Baek JW, Kasahara DI, Anathy V, Israel E, Park JA.

J Allergy Clin Immunol. 2019 10. 144(4):1116-1118.e4. PMID: 31228474

Pulmonary Neuroendocrine Cells Secrete ?-Aminobutyric Acid to Induce Goblet Cell Hyperplasia in Primate Models.

Barrios J, Kho AT, Aven L, Mitchel JA, Park JA, Randell SH, Miller LA, Tantisira KG, Ai X.

Am J Respir Cell Mol Biol. 2019 06. 60(6):687-694. PMID: 30571139

The tumor suppressor p53 can promote collective cellular migration.

He S, Carman CV, Lee JH, Lan B, Koehler S, Atia L, Park CY, Kim JH, Mitchel JA, Park JA, Butler JP, Lu Q, Fredberg JJ.

PLoS One. 2019. 14(2):e0202065. PMID: 30707705