Early overnutrition in male mice negates metabolic benefits of a diet high in monounsaturated and omega-3 fats.
Glavas MM, Hui Q, Miao I, Yang F, Erener S, Prentice KJ, Wheeler MB, Kieffer TJ.
Sci Rep. 2021 Jul 07. 11(1):14032. PMID: 34234216
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Bibliography
Adipokine FABP4 integrates energy stores and counterregulatory metabolic responses.
Prentice KJ, Saksi J, Hotamisligil GS.
J Lipid Res. 2019 04. 60(4):734-740. PMID: 30705117
3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF) prevents high fat diet-induced insulin resistance via maintenance of hepatic lipid homeostasis.
Mohan H, Brandt SL, Kim JH, Wong F, Lai M, Prentice KJ, Al Rijjal D, Magomedova L, Batchuluun B, Burdett E, Bhattacharjee A, Cummins CL, Belsham DD, Cox B, Liu Y, Wheeler MB.
Diabetes Obes Metab. 2019 01. 21(1):61-72. PMID: 30062833
Glucolipotoxic conditions induce ß-cell iron import, cytosolic ROS formation and apoptosis.
Hansen JB, Dos Santos LRB, Liu Y, Prentice KJ, Teudt F, Tonnesen M, Jonas JC, Wheeler MB, Mandrup-Poulsen T.
J Mol Endocrinol. 2018 08. 61(2):69-77. PMID: 30030388
Elevated Medium-Chain Acylcarnitines Are Associated With Gestational Diabetes Mellitus and Early Progression to Type 2 Diabetes and Induce Pancreatic ß-Cell Dysfunction.
Batchuluun B, Al Rijjal D, Prentice KJ, Eversley JA, Burdett E, Mohan H, Bhattacharjee A, Gunderson EP, Liu Y, Wheeler MB.
Diabetes. 2018 05. 67(5):885-897. PMID: 29436377
CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis.
Prentice KJ, Wendell SG, Liu Y, Eversley JA, Salvatore SR, Mohan H, Brandt SL, Adams AC, Serena Wang X, Wei D, FitzGerald GA, Durham TB, Hammond CD, Sloop KW, Skarke C, Schopfer FJ, Wheeler MB.
EBioMedicine. 2018 Jan. 27:200-213. PMID: 29290411
Synthesis and Characterization of Urofuranoic Acids: In Vivo Metabolism of 2-(2-Carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic Acid (CMPF) and Effects on in Vitro Insulin Secretion.
Nagy E, Liu Y, Prentice KJ, Sloop KW, Sanders PE, Batchuluun B, Hammond CD, Wheeler MB, Durham TB.
J Med Chem. 2017 03 09. 60(5):1860-1875. PMID: 28171722
New Roles of Syntaxin-1A in Insulin Granule Exocytosis and Replenishment.
Liang T, Qin T, Xie L, Dolai S, Zhu D, Prentice KJ, Wheeler M, Kang Y, Osborne L, Gaisano HY.
J Biol Chem. 2017 02 10. 292(6):2203-2216. PMID: 28031464
A Predictive Metabolic Signature for the Transition From Gestational Diabetes Mellitus to Type 2 Diabetes.
Allalou A, Nalla A, Prentice KJ, Liu Y, Zhang M, Dai FF, Ning X, Osborne LR, Cox BJ, Gunderson EP, Wheeler MB.
Diabetes. 2016 09. 65(9):2529-39. PMID: 27338739
Rapid Elevation in CMPF May Act As a Tipping Point in Diabetes Development.
Liu Y, Prentice KJ, Eversley JA, Hu C, Batchuluun B, Leavey K, Hansen JB, Wei DW, Cox B, Dai FF, Jia W, Wheeler MB.
Cell Rep. 2016 Mar 29. 14(12):2889-900. PMID: 26997281