Karestan Koenen
Professor

Karestan Koenen

Professor of Psychiatric Epidemiology

Epidemiology

kkoenen@hsph.harvard.edu

Other Positions

Faculty Affiliate in the Department of Social and Behavioral Sciences

Social and Behavioral Sciences

Harvard T.H. Chan School of Public Health


Overview

Karestan C. Koenen, PhD aims to reduce the population burden of mental disorders through research, training, and advocacy. She is passionate about using science to overcome violence and trauma, which are major preventable causes of health problems globally.

Research
Dr. Koenen's research focus is three-fold. First, she studies why some people develop PTSD and related mental and physical health problems and why some people are resilient when exposed to similar traumatic events. Dr. Koenen is a co-principal investigator on the NIMH-funded AURORA study, led by Dr. Samuel McLean with Drs. Ronald Kessler and Kerry Ressler. Dr. Koenen also co-leads the PTSD working group of the Psychiatric Genomics Consortium, which aims to identify genetic variants that increase risk and resilience following trauma exposure. Second, she investigates how violence, trauma, and PTSD alter long-term physical health and accelerate aging. Much of this work is done in collaboration with the Nurses' Health Study. Third, she aims to expand access to evidence-based mental health treatment for survivors of violence and trauma. To this end, she co-wrote the book, Treating Survivors of Childhood Abuse: Psychotherapy for the Interrupted Life with Drs. Marylene Cloitre and Lisa Cohen.

Training
Dr. Koenen leads the NIMH-funded Training Program in Psychiatric Epidemiology and Biostatistics (T32) and the Interdisciplinary Concentration in Population Mental Health. She also advises masters and doctoral degree students in the Departments of Epidemiology and Social Behavioral Sciences. In addition, Dr. Koenen leads the Trauma Epidemiology and Population Mental Health Research Group for her students and post-doctoral fellows. The group is primarily a forum for trainees and junior investigators to present and receive feedback on work-in-progress, but also includes presentations on advanced research methodology and career development.

Advocacy
Dr. Koenen advocates for survivors of violence and trauma. In May 2011, Dr. Koenen testified before the House Foreign Affairs Full Committee about the epidemic of sexual violence and victim blaming culture of the Peace Corps. She has written for the Boston Globe, the Washington Post, the Huffington Post, and the Women's Media Center's Women Under Siege Project, which investigates how rape and other forms of sexualized violence are used as tools in conflict. Dr. Koenen also consulted on the documentary, It Happened Here, which examined the epidemic of sexual assault on university campuses. In addition, Dr. Koenen speaks to lay audiences about the latest scientific findings around violence and trauma.


Bibliography

Low-coverage sequencing cost-effectively detects known and novel variation in underrepresented populations.

Martin AR, Atkinson EG, Chapman SB, Stevenson A, Stroud RE, Abebe T, Akena D, Alemayehu M, Ashaba FK, Atwoli L, Bowers T, Chibnik LB, Daly MJ, DeSmet T, Dodge S, Fekadu A, Ferriera S, Gelaye B, Gichuru S, Injera WE, James R, Kariuki SM, Kigen G, Koenen KC, Kwobah E, Kyebuzibwa J, Majara L, Musinguzi H, Mwema RM, Neale BM, Newman CP, Newton CRJC, Pickrell JK, Ramesar R, Shiferaw W, Stein DJ, Teferra S, van der Merwe C, Zingela Z.

Am J Hum Genet. 2021 Apr 01. 108(4):656-668. PMID: 33770507

Prior sleep problems and adverse post-traumatic neuropsychiatric sequelae of motor vehicle collision in the AURORA study.

Neylan TC, Kessler RC, Ressler KJ, Clifford G, Beaudoin FL, An X, Stevens JS, Zeng D, Linnstaedt SD, Germine LT, Sheikh S, Storrow AB, Punches BE, Mohiuddin K, Gentile NT, McGrath ME, van Rooij SJH, Haran JP, Peak DA, Domeier RM, Pearson C, Sanchez LD, Rathlev NK, Peacock WF, Bruce SE, Joormann J, Barch DM, Pizzagalli DA, Sheridan JF, Harte SE, Elliott JM, Hwang I, Petukhova MV, Sampson NA, Koenen KC, McLean SA.

Sleep. 2021 Mar 12. 44(3). PMID: 32975289

Perceived major experiences of discrimination, ethnic group, and risk of psychosis in a six-country case-control study.

Misra S, Gelaye B, Williams DR, Koenen KC, Borba CPC, Quattrone D, Di Forti M, Tripoli G, La Cascia C, La Barbera D, Ferraro L, Tarricone I, Berardi D, Lasalvia A, Tosato S, Szöke A, Llorca PM, Arango C, Tortelli A, de Haan L, Velthorst E, Bobes J, Bernardo M, Sanjuán J, Santos JL, Arrojo M, Del-Ben CM, Menezes PR, Selten JP, Jones PB, Jongsma HE, Kirkbride JB, Rutten BPF, van Os J, Murray RM, Gayer-Anderson C, Morgan C.

Psychol Med. 2021 Mar 02. 1-9. PMID: 33648622


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