Research Fellows

Katelyn M Brenneman

Postdoctoral Fellow

Immunology and Infectious Diseases

kbrenneman@hsph.harvard.edu

Links

Catalyst Profile

Education and Training

PhD, 05/2022, Biological Sciences
University of Notre Dame, Notre Dame, IN

BA, 12/2015, Molecular biology/Biochemistry
Goshen College, Goshen, IN

Bibliography

A Plasmodium falciparum genetic cross reveals the contributions of pfcrt and plasmepsin II/III to piperaquine drug resistance.

Kane J, Li X, Kumar S, Button-Simons KA, Brenneman KMV, Dahlhoff H, Sievert MAC, Checkley LA, Shoue DA, Singh PP, Abatiyow BA, Haile MT, Nair S, Reyes A, Tripura R, Peto T, Lek D, Kappe SHI, Dhorda M, Nkhoma SC, Cheeseman IH, Vaughan AM, Anderson TJC, Ferdig MT.

bioRxiv. 2023 Sep 17. PMID: 37745488

Chloroquine resistance evolution in Plasmodium falciparum is mediated by the putative amino acid transporter AAT1.

Amambua-Ngwa A, Button-Simons KA, Li X, Kumar S, Brenneman KV, Ferrari M, Checkley LA, Haile MT, Shoue DA, McDew-White M, Tindall SM, Reyes A, Delgado E, Dalhoff H, Larbalestier JK, Amato R, Pearson RD, Taylor AB, Nosten FH, D'Alessandro U, Kwiatkowski D, Cheeseman IH, Kappe SHI, Avery SV, Conway DJ, Vaughan AM, Ferdig MT, Anderson TJC.

Nat Microbiol. 2023 07. 8(7):1213-1226. PMID: 37169919

Bulk segregant linkage mapping for rodent and human malaria parasites.

Li X, Kumar S, Brenneman KV, Anderson TJC.

Parasitol Int. 2022 Dec. 91:102653. PMID: 36007706

A Malaria Parasite Cross Reveals Genetic Determinants of Plasmodium falciparum Growth in Different Culture Media.

Kumar S, Li X, McDew-White M, Reyes A, Delgado E, Sayeed A, Haile MT, Abatiyow BA, Kennedy SY, Camargo N, Checkley LA, Brenneman KV, Button-Simons KA, Duraisingh MT, Cheeseman IH, Kappe SHI, Nosten F, Ferdig MT, Vaughan AM, Anderson TJC.

Front Cell Infect Microbiol. 2022. 12:878496. PMID: 35711667

Optimizing bulk segregant analysis of drug resistance using Plasmodium falciparum genetic crosses conducted in humanized mice.

Brenneman KV, Li X, Kumar S, Delgado E, Checkley LA, Shoue DA, Reyes A, Abatiyow BA, Haile MT, Tripura R, Peto T, Lek D, Button-Simons KA, Kappe SHI, Dhorda M, Nosten F, Nkhoma SC, Cheeseman IH, Vaughan AM, Ferdig MT, Anderson TJC.

iScience. 2022 Apr 15. 25(4):104095. PMID: 35372813

Cyclical regression covariates remove the major confounding effect of cyclical developmental gene expression with strain-specific drug response in the malaria parasite Plasmodium falciparum.

Foster GJ, Sievert MAC, Button-Simons K, Vendrely KM, Romero-Severson J, Ferdig MT.

BMC Genomics. 2022 Mar 05. 23(1):180. PMID: 35247977

Humanized Mice and the Rebirth of Malaria Genetic Crosses.

Vendrely KM, Kumar S, Li X, Vaughan AM.

Trends Parasitol. 2020 10. 36(10):850-863. PMID: 32891493

The extended recovery ring-stage survival assay provides a superior association with patient clearance half-life and increases throughput.

Davis SZ, Singh PP, Vendrely KM, Shoue DA, Checkley LA, McDew-White M, Button-Simons KA, Cassady Z, Sievert MAC, Foster GJ, Nosten FH, Anderson TJC, Ferdig MT.

Malar J. 2020 Jan 31. 19(1):54. PMID: 32005233

Pairwise growth competitions identify relative fitness relationships among artemisinin resistant Plasmodium falciparum field isolates.

Tirrell AR, Vendrely KM, Checkley LA, Davis SZ, McDew-White M, Cheeseman IH, Vaughan AM, Nosten FH, Anderson TJC, Ferdig MT.

Malar J. 2019 Aug 28. 18(1):295. PMID: 31462253

Leveraging crowdsourcing to accelerate global health solutions.

Davis S, Button-Simons K, Bensellak T, Ahsen EM, Checkley L, Foster GJ, Su X, Moussa A, Mapiye D, Khoo SK, Nosten F, Anderson TJC, Vendrely K, Bletz J, Yu T, Panji S, Ghouila A, Mulder N, Norman T, Kern S, Meyer P, Stolovitzky G, Ferdig MT, Siwo GH.

Nat Biotechnol. 2019 08. 37(8):848-850. PMID: 31324891

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