Kizzmekia S Corbett
Assistant Professor

Kizzmekia S Corbett

Assistant Professor of Immunology and Infectious Diseases

Immunology and Infectious Diseases

kizzmekia_corbett@hsph.harvard.edu


Overview

Dr. Corbett uses her viral immunology expertise to propel novel vaccine development for pandemic preparedness, including mRNA-1273, a leading vaccine against SARS-CoV-2. The vaccine concept incorporated in mRNA-1273 was designed by Dr. Corbett's NIH team from viral sequence and rapidly deployed to industry partner, Moderna, Inc., for Phase 1 clinical trial, which unprecedently began only 66 days from viral sequence release. mRNA-1273 was shown to be 94.1% effective in Phase 3 trial and is authorized for use in multiple countries. Alongside mRNA-1273, Dr. Corbett boasts a patent portfolio which also includes universal coronavirus and influenza vaccine concepts and novel therapeutic antibodies. In all, she has over 15 years of experience studying dengue virus, respiratory syncytial virus, influenza virus, and coronaviruses, garnering several prestigious awards, such as the Benjamin Franklin Next Gen Award and the Salzman Memorial Award in Virology. Combining her research goals with her knack for mentorship, Dr. Corbett invests much of her time in underserved communities as an advocator of STEM education and vaccine awareness.

BSc, 2008, Bachelor of Science in Biological Sciences | Secondary Major in Sociology
University of Maryland, Baltimore County

PhD, 2014, Doctor of Philosophy in Microbiology and Immunology
University of North Carolina, Chapel Hill (UNC)

Proclamation: “Dr. Kizzmekia ‘Kizzy’ Day” – January 2801-2021
Town of Chapel Hill

Hall of FAME Honoree02-2021
City of Los Angeles

Key of Life Award02-2021
National Association for the Advancement of Colored People

Benjamin Franklin NextGen Award04-2021
The Franklin Institute

Scroll of Merit Award04-2021
National Medical Association

Dean’s Medal05-2021
Johns Hopkins Bloomberg School of Public Health

Clinton Global Citizen Award05-2021
Clinton Foundation

Mrs. Rosa Parks Hidden Figure Award06-2021
Rosa and Raymond Parks Institute and the O Museum

Early Career Applied and Biotechnological Research Award08-2020
American Society for Microbiology

Distinguished 400 Award09-2020
400 Years of African American History Commission

Theodore Roosevelt Government Leadership Award10-2020
Government Executive Media Group

NIAID Merit Award11-2020
NHP COVID Vaccine Core

The Golden Goose Award12-2020
American Association for the Advancement of Science (AAAS)


Bibliography

Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit.

Hall MD, Anderson JM, Anderson A, Baker D, Bradner J, Brimacombe KR, Campbell EA, Corbett KS, Carter K, Cherry S, Chiang L, Cihlar T, de Wit E, Denison M, Disney M, Fletcher CV, Ford-Scheimer SL, Götte M, Grossman AC, Hayden FG, Hazuda DJ, Lanteri CA, Marston H, Mesecar AD, Moore S, Nwankwo JO, O'Rear J, Painter G, Singh Saikatendu K, Schiffer CA, Sheahan TP, Shi PY, Smyth HD, Sofia MJ, Weetall M, Weller SK, Whitley R, Fauci AS, Austin CP, Collins FS, Conley AJ, Davis MI.

J Infect Dis. 2021 Jul 15. 224(Supplement_1):S1-S21. PMID: 34111271

Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.

Wang L, Zhou T, Zhang Y, Yang ES, Schramm CA, Shi W, Pegu A, Oloniniyi OK, Henry AR, Darko S, Narpala SR, Hatcher C, Martinez DR, Tsybovsky Y, Phung E, Abiona OM, Antia A, Cale EM, Chang LA, Choe M, Corbett KS, Davis RL, DiPiazza AT, Gordon IJ, Helmold Hait S, Hermanus T, Kgagudi P, Laboune F, Leung K, Liu T, Mason RD, Nazzari AF, Novik L, O'Connell S, O'Dell S, Olia AS, Schmidt SD, Stephens T, Stringham CD, Talana CA, Teng IT, Wagner DA, Widge AT, Zhang B, Roederer M, Ledgerwood JE, Ruckwardt TJ, Gaudinski MR, Moore PL, Doria-Rose NA, Baric RS, Graham BS, McDermott AB, Douek DC, Kwong PD, Mascola JR, Sullivan NJ, Misasi J.

Science. 2021 Jul 01. PMID: 34210892

Evaluation of mRNA-1273 against SARS-CoV-2 B.1.351 Infection in Nonhuman Primates.

Corbett KS, Werner AP, O' Connell S, Gagne M, Lai L, Moliva JI, Flynn B, Choi A, Koch M, Foulds KE, Andrew SF, Flebbe DR, Lamb E, Nurmukhambetova ST, Provost SJ, Bock KW, Minai M, Nagata BM, Van Ry A, Flinchbaugh Z, Johnston TS, Mokhtari EB, Mudvari P, Henry AR, Laboune F, Chang B, Porto M, Wear J, Alvarado GS, Boyoglu-Barnum S, Todd JM, Bart B, Cook A, Dodson A, Pessaint L, Steingrebe K, Elbashir S, Andersen H, Wu K, Edwards DK, Kar S, Lewis MG, Bortiz E, Moore IN, Carfi A, Suthar MS, McDermott A, Roederer M, Nason MC, Sullivan NJ, Douek DC, Graham BS, Seder RA.

bioRxiv. 2021 May 24. PMID: 34075375

Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants.

Pegu A, O'Connell S, Schmidt SD, O'Dell S, Talana CA, Lai L, Albert J, Anderson E, Bennett H, Corbett KS, Flach B, Jackson L, Leav B, Ledgerwood JE, Luke CJ, Makowski M, Roberts PC, Roederer M, Rebolledo PA, Rostad CA, Rouphael NG, Shi W, Wang L, Widge AT, Yang ES, Beigel JH, Graham BS, Mascola JR, Suthar MS, McDermott A, Doria-Rose NA.

bioRxiv. 2021 May 16. PMID: 34031659

LY-CoV1404 potently neutralizes SARS-CoV-2 variants.

Westendorf K, Žentelis S, Foster D, Vaillancourt P, Wiggin M, Lovett E, Hendle J, Pustilnik A, Sauder JM, Kraft L, Hwang Y, Siegel RW, Chen J, Heinz BA, Higgs RE, Kalleward N, Jepson K, Goya R, Smith MA, Collins DW, Pellacani D, Xiang P, de Puyraimond V, Ricicova M, Devorkin L, Pritchard C, O'Neill A, Cohen C, Dye J, Huie KI, Badger CV, Kobasa D, Audet J, Freitas JJ, Hassanali S, Hughes I, Munoz L, Palma HC, Ramamurthy B, Cross RW, Geisbert TW, Borisevich V, Lanz I, Anderson L, Sipahimalani P, Corbett KS, Wang L, Yang ES, Zhang Y, Shi W, Graham BS, Mascola JR, Fernandez TL, Hansen CL, Falconer E, Jones BE, Barnhart BC.

bioRxiv. 2021 May 04. PMID: 33972947

Immune Correlates of Protection by mRNA-1273 Immunization against SARS-CoV-2 Infection in Nonhuman Primates.

Corbett KS, Nason MC, Flach B, Gagne M, O' Connell S, Johnston TS, Shah SN, Edara VV, Floyd K, Lai L, McDanal C, Francica JR, Flynn B, Wu K, Choi A, Koch M, Abiona OM, Werner AP, Alvarado GS, Andrew SF, Donaldson MM, Fintzi J, Flebbe DR, Lamb E, Noe AT, Nurmukhambetova ST, Provost SJ, Cook A, Dodson A, Faudree A, Greenhouse J, Kar S, Pessaint L, Porto M, Steingrebe K, Valentin D, Zouantcha S, Bock KW, Minai M, Nagata BM, Moliva JI, van de Wetering R, Boyoglu-Barnum S, Leung K, Shi W, Yang ES, Zhang Y, Todd JM, Wang L, Andersen H, Foulds KE, Edwards DK, Mascola JR, Moore IN, Lewis MG, Carfi A, Montefiori D, Suthar MS, McDermott A, Sullivan NJ, Roederer M, Douek DC, Graham BS, Seder RA.

bioRxiv. 2021 Apr 23. PMID: 33907752