Data-Driven Polymer Model for Mechanistic Exploration of Diploid Genome Organization.
Qi Y, Reyes A, Johnstone SE, Aryee MJ, Bernstein BE, Zhang B.
Biophys J. 2020 Nov 03. 119(9):1905-1916. PMID: 33086041
Assistant Professor
Martin Aryee
Other Positions
Assistant Professor of Pathology
Pathology
Massachusetts General Hospital
Links
Bibliography
Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer.
Johnstone SE, Reyes A, Qi Y, Adriaens C, Hegazi E, Pelka K, Chen JH, Zou LS, Drier Y, Hecht V, Shoresh N, Selig MK, Lareau CA, Iyer S, Nguyen SC, Joyce EF, Hacohen N, Irizarry RA, Zhang B, Aryee MJ, Bernstein BE.
Cell. 2020 Sep 17. 182(6):1474-1489.e23. PMID: 32841603
Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling.
Lareau CA, Ludwig LS, Muus C, Gohil SH, Zhao T, Chiang Z, Pelka K, Verboon JM, Luo W, Christian E, Rosebrock D, Getz G, Boland GM, Chen F, Buenrostro JD, Hacohen N, Wu CJ, Aryee MJ, Regev A, Sankaran VG.
Nat Biotechnol. 2020 Aug 12. PMID: 32788668
Author Correction: Feature selection and dimension reduction for single-cell RNA-Seq based on a multinomial model.
Townes FW, Hicks SC, Aryee MJ, Irizarry RA.
Genome Biol. 2020 Jul 22. 21(1):179. PMID: 32698904
Publisher Correction: Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.
Kleinstiver BP, Sousa AA, Walton RT, Tak YE, Hsu JY, Clement K, Welch MM, Horng JE, Malagon-Lopez J, Scarfò I, Maus MV, Pinello L, Aryee MJ, Joung JK.
Nat Biotechnol. 2020 Jul. 38(7):901. PMID: 32541959
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing.
Grünewald J, Zhou R, Lareau CA, Garcia SP, Iyer S, Miller BR, Langner LM, Hsu JY, Aryee MJ, Joung JK.
Nat Biotechnol. 2020 07. 38(7):861-864. PMID: 32483364
Feature selection and dimension reduction for single-cell RNA-Seq based on a multinomial model.
Townes FW, Hicks SC, Aryee MJ, Irizarry RA.
Genome Biol. 2019 12 23. 20(1):295. PMID: 31870412
High levels of AAV vector integration into CRISPR-induced DNA breaks.
Hanlon KS, Kleinstiver BP, Garcia SP, Zaborowski MP, Volak A, Spirig SE, Muller A, Sousa AA, Tsai SQ, Bengtsson NE, Lööv C, Ingelsson M, Chamberlain JS, Corey DP, Aryee MJ, Joung JK, Breakefield XO, Maguire CA, György B.
Nat Commun. 2019 09 30. 10(1):4439. PMID: 31570731
CRISPR DNA base editors with reduced RNA off-target and self-editing activities.
Grünewald J, Zhou R, Iyer S, Lareau CA, Garcia SP, Aryee MJ, Joung JK.
Nat Biotechnol. 2019 09. 37(9):1041-1048. PMID: 31477922
Magnetic Resonance Spectroscopy-based Metabolomic Biomarkers for Typing, Staging, and Survival Estimation of Early-Stage Human Lung Cancer.
Berker Y, Vandergrift LA, Wagner I, Su L, Kurth J, Schuler A, Dinges SS, Habbel P, Nowak J, Mark E, Aryee MJ, Christiani DC, Cheng LL.
Sci Rep. 2019 07 16. 9(1):10319. PMID: 31311965