Augmenting and directing long-range CRISPR-mediated activation in human cells.
Tak YE, Horng JE, Perry NT, Schultz HT, Iyer S, Yao Q, Zou LS, Aryee MJ, Pinello L, Joung JK.
Nat Methods. 2021 09. 18(9):1075-1081. PMID: 34354266
Associate Professor
Martin Aryee
Other Positions
Associate Professor of Pathology
Pathology
Massachusetts General Hospital
Links
Bibliography
Smart-RRBS for single-cell methylome and transcriptome analysis.
Gu H, Raman AT, Wang X, Gaiti F, Chaligne R, Mohammad AW, Arczewska A, Smith ZD, Landau DA, Aryee MJ, Meissner A, Gnirke A.
Nat Protoc. 2021 08. 16(8):4004-4030. PMID: 34244697
STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma.
Adane B, Alexe G, Seong BKA, Lu D, Hwang EE, Hnisz D, Lareau CA, Ross L, Lin S, Dela Cruz FS, Richardson M, Weintraub AS, Wang S, Iniguez AB, Dharia NV, Conway AS, Robichaud AL, Tanenbaum B, Krill-Burger JM, Vazquez F, Schenone M, Berman JN, Kung AL, Carr SA, Aryee MJ, Young RA, Crompton BD, Stegmaier K.
Cancer Cell. 2021 Jun 14. 39(6):827-844.e10. PMID: 34129824
Extended-representation bisulfite sequencing of gene regulatory elements in multiplexed samples and single cells.
Shareef SJ, Bevill SM, Raman AT, Aryee MJ, van Galen P, Hovestadt V, Bernstein BE.
Nat Biotechnol. 2021 09. 39(9):1086-1094. PMID: 33958785
Data-Driven Polymer Model for Mechanistic Exploration of Diploid Genome Organization.
Qi Y, Reyes A, Johnstone SE, Aryee MJ, Bernstein BE, Zhang B.
Biophys J. 2020 11 03. 119(9):1905-1916. PMID: 33086041
Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer.
Johnstone SE, Reyes A, Qi Y, Adriaens C, Hegazi E, Pelka K, Chen JH, Zou LS, Drier Y, Hecht V, Shoresh N, Selig MK, Lareau CA, Iyer S, Nguyen SC, Joyce EF, Hacohen N, Irizarry RA, Zhang B, Aryee MJ, Bernstein BE.
Cell. 2020 09 17. 182(6):1474-1489.e23. PMID: 32841603
Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling.
Lareau CA, Ludwig LS, Muus C, Gohil SH, Zhao T, Chiang Z, Pelka K, Verboon JM, Luo W, Christian E, Rosebrock D, Getz G, Boland GM, Chen F, Buenrostro JD, Hacohen N, Wu CJ, Aryee MJ, Regev A, Sankaran VG.
Nat Biotechnol. 2021 04. 39(4):451-461. PMID: 32788668
Author Correction: Feature selection and dimension reduction for single-cell RNA-Seq based on a multinomial model.
Townes FW, Hicks SC, Aryee MJ, Irizarry RA.
Genome Biol. 2020 Jul 22. 21(1):179. PMID: 32698904
Publisher Correction: Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.
Kleinstiver BP, Sousa AA, Walton RT, Tak YE, Hsu JY, Clement K, Welch MM, Horng JE, Malagon-Lopez J, Scarfò I, Maus MV, Pinello L, Aryee MJ, Joung JK.
Nat Biotechnol. 2020 Jul. 38(7):901. PMID: 32541959
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing.
Grünewald J, Zhou R, Lareau CA, Garcia SP, Iyer S, Miller BR, Langner LM, Hsu JY, Aryee MJ, Joung JK.
Nat Biotechnol. 2020 07. 38(7):861-864. PMID: 32483364