Masahiro Takeuchi

A variant in human AIOLOS impairs adaptive immunity by interfering with IKAROS.

Yamashita M, Kuehn HS, Okuyama K, Okada S, Inoue Y, Mitsuiki N, Imai K, Takagi M, Kanegane H, Takeuchi M, Shimojo N, Tsumura M, Padhi AK, Zhang KYJ, Boisson B, Casanova JL, Ohara O, Rosenzweig SD, Taniuchi I, Morio T.

Nat Immunol. 2021 Jul. 22(7):893-903. PMID: 34155405

The combination of the tubulin binding small molecule PTC596 and proteasome inhibitors suppresses the growth of myeloma cells.

Nagai Y, Mimura N, Rizq O, Isshiki Y, Oshima M, Rizk M, Saraya A, Koide S, Nakajima-Takagi Y, Miyota M, Chiba T, Oshima-Hasegawa N, Muto T, Tsukamoto S, Mitsukawa S, Takeda Y, Ohwada C, Takeuchi M, Iseki T, Nakaseko C, Lennox W, Sheedy J, Weetall M, Yokote K, Iwama A, Sakaida E.

Sci Rep. 2021 Jan 22. 11(1):2074. PMID: 33483574

Neutrophils interact with cholangiocytes to cause cholestatic changes in alcoholic hepatitis.

Takeuchi M, Vidigal PT, Guerra MT, Hundt MA, Robert ME, Olave-Martinez M, Aoki S, Khamphaya T, Kersten R, Kruglov E, de la Rosa Rodriguez R, Banales JM, Nathanson MH, Weerachayaphorn J.

Gut. 2021 Feb. 70(2):342-356. PMID: 33214166

Intensive treat-to-target statin therapy and severity of diabetic retinopathy complicated by hypercholesterolaemia.

Murakami T, Kato S, Shigeeda T, Itoh H, Komuro I, Takeuchi M, Yoshimura N.

Eye (Lond). 2020 Oct 26. PMID: 33106609

The critical role of CD4+ T cells in PD-1 blockade against MHC-II-expressing tumors such as classic Hodgkin lymphoma.

Nagasaki J, Togashi Y, Sugawara T, Itami M, Yamauchi N, Yuda J, Sugano M, Ohara Y, Minami Y, Nakamae H, Hino M, Takeuchi M, Nishikawa H.

Blood Adv. 2020 09 08. 4(17):4069-4082. PMID: 32870971

Phase 2 study of irinotecan plus cetuximab rechallenge as third-line treatment in KRAS wild-type metastatic colorectal cancer: JACCRO CC-08.

Masuishi T, Tsuji A, Kotaka M, Nakamura M, Kochi M, Takagane A, Shimada K, Denda T, Segawa Y, Tanioka H, Hara H, Sagawa T, Watanabe T, Takahashi T, Negoro Y, Manaka D, Fujita H, Suto T, Takeuchi M, Ichikawa W, Fujii M.

Br J Cancer. 2020 11. 123(10):1490-1495. PMID: 32863385

Clinical impact of the radiological indeterminate for usual interstitial pneumonia pattern on the diagnosis of idiopathic pulmonary fibrosis.

Inomata M, Jo T, Kuse N, Awano N, Tone M, Yoshimura H, Moriya A, Bae Y, Terada Y, Furuhata Y, Kumasaka T, Ushiwata A, Harada A, Terasaki Y, Takeuchi M, Sugiura H, Takemura T, Izumo T.

Respir Investig. 2021 Jan. 59(1):81-89. PMID: 32868263

The Lymphocyte-to-monocyte Ratio Is an Independent Prognostic Indicator in Pancreatic Head Cancer that Correlates With Obstructive Jaundice.

Takeuchi M, Mitsuyoshi M, Yoshida K, Onoda M, Iwamura M, Furutani A, Kawano K, Katoh T.

Anticancer Res. 2020 Jun. 40(6):3371-3377. PMID: 32487633

Influence of chemoradiotherapy on nutritional status in locally advanced rectal cancer: Prospective multicenter study.

Yamano T, Tomita N, Sato T, Hayakawa K, Kamikonya N, Matoba S, Uki A, Baba H, Oya N, Hasegawa H, Shigematsu N, Hiraoka M, Shimada M, Noda M, Sakai Y, Sato H, Saegusa M, Takeuchi M, Oguchi M, Oya M, Watanabe M.

Nutrition. 2020 09. 77:110807. PMID: 32402940

Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade.

Nakao S, Arai Y, Tasaki M, Yamashita M, Murakami R, Kawase T, Amino N, Nakatake M, Kurosaki H, Mori M, Takeuchi M, Nakamura T.

Sci Transl Med. 2020 01 15. 12(526). PMID: 31941828