Michael Chase

CD4 T cells and CD8a+ lymphocytes are necessary for intravenous BCG-induced protection against tuberculosis in macaques.

Simonson AW, Zeppa JJ, Bucsan AN, Chao MC, Pokkali S, Hopkins F, Chase MR, Vickers AJ, Sutton MS, Winchell CG, Myers AJ, Ameel CL, Kelly R, Krouse B, Hood LE, Li J, Lehman CC, Kamath M, Tomko J, Rodgers MA, Donlan R, Chishti H, Jacob Borish H, Klein E, Scanga CA, Fortune S, Lin PL, Maiello P, Roederer M, Darrah PA, Seder RA, Flynn JL.

bioRxiv. 2024 May 17. PMID: 38798646

Identification of bacterial determinants of tuberculosis infection and treatment outcomes: a phenogenomic analysis of clinical strains.

Stanley S, Spaulding CN, Liu Q, Chase MR, Ha DTM, Thai PVK, Lan NH, Thu DDA, Quang NL, Brown J, Hicks ND, Wang X, Marin M, Howard NC, Vickers AJ, Karpinski WM, Chao MC, Farhat MR, Caws M, Dunstan SJ, Thuong NTT, Fortune SM.

Lancet Microbe. 2024 Jun. 5(6):e570-e580. PMID: 38734030

Mycobacterial RNase E cleaves with a distinct sequence preference and controls the degradation rates of most Mycolicibacterium smegmatis mRNAs.

Zhou Y, Sun H, Rapiejko AR, Vargas-Blanco DA, Martini MC, Chase MR, Joubran SR, Davis AB, Dainis JP, Kelly JM, Ioerger TR, Roberts LA, Fortune SM, Shell SS.

J Biol Chem. 2023 11. 299(11):105312. PMID: 37802316

High-throughput phenogenotyping of Mycobacteria tuberculosis clinical strains reveals bacterial determinants of treatment outcomes.

Stanley S, Spaulding CN, Liu Q, Chase MR, Ha DTM, Thai PVK, Lan NH, Thu DDA, Quang NL, Brown J, Hicks ND, Wang X, Marin M, Howard NC, Vickers AJ, Karpinski WM, Chao MC, Farhat MR, Caws M, Dunstan SJ, Thuong NTT, Fortune SM.

bioRxiv. 2023 Apr 10. PMID: 37090677

Arginine methylation sites on SepIVA help balance elongation and septation in Mycobacterium smegmatis.

Freeman AH, Tembiwa K, Brenner JR, Chase MR, Fortune SM, Morita YS, Boutte CC.

Mol Microbiol. 2023 02. 119(2):208-223. PMID: 36416406

Spontaneous Control of SIV Replication Does Not Prevent T Cell Dysregulation and Bacterial Dissemination in Animals Co-Infected with M. tuberculosis.

Moriarty RV, Rodgers MA, Ellis AL, Balgeman AJ, Larson EC, Hopkins F, Chase MR, Maiello P, Fortune SM, Scanga CA, O'Connor SL.

Microbiol Spectr. 2022 06 29. 10(3):e0172421. PMID: 35467372

CRISPR Interference Reveals That All-Trans-Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to Cholesterol and Propionyl Coenzyme A.

Babunovic GH, DeJesus MA, Bosch B, Chase MR, Barbier T, Dickey AK, Bryson BD, Rock JM, Fortune SM.

mBio. 2022 02 22. 13(1):e0368321. PMID: 35038923

ClpX Is Essential and Activated by Single-Strand DNA Binding Protein in Mycobacteria.

Kester JC, Kandror O, Akopian T, Chase MR, Zhu J, Rubin EJ, Goldberg AL, Fortune SM.

J Bacteriol. 2021 01 25. 203(4). PMID: 33229461

Correction: TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities.

Carey AF, Rock JM, Krieger IV, Chase MR, Fernandez-Suarez M, Gagneux S, Sacchettini JC, Ioerger TR, Fortune SM.

PLoS Pathog. 2019 Jun. 15(6):e1007846. PMID: 31163081

Small RNA profiling in Mycobacterium tuberculosis identifies MrsI as necessary for an anticipatory iron sparing response.

Gerrick ER, Barbier T, Chase MR, Xu R, François J, Lin VH, Szucs MJ, Rock JM, Ahmad R, Tjaden B, Livny J, Fortune SM.

Proc Natl Acad Sci U S A. 2018 06 19. 115(25):6464-6469. PMID: 29871950