Improved Antitumor Efficacy of Chimeric Antigen Receptor T Cells that Secrete Single-Domain Antibody Fragments.
Xie YJ, Dougan M, Ingram JR, Pishesha N, Fang T, Momin N, Ploegh HL.
Cancer Immunol Res. 2020 04. 8(4):518-529. PMID: 32019780
Fellow or Post Doc
Novalia Pishesha
Postdoctoral Fellow
Immunology and Infectious Diseases
Other Positions
Junior Fellow of the Society of Fellows
Soc of Fellows
Faculty of Arts & Sciences
Instructor in Pediatrics
Pediatrics
Boston Children's Hospital
Links
Bibliography
Nanobody-based CAR T cells that target the tumor microenvironment inhibit the growth of solid tumors in immunocompetent mice.
Xie YJ, Dougan M, Jailkhani N, Ingram J, Fang T, Kummer L, Momin N, Pishesha N, Rickelt S, Hynes RO, Ploegh H.
Proc Natl Acad Sci U S A. 2019 04 16. 116(16):7624-7631. PMID: 30936321
Improving hematopoietic recovery through modeling and modulation of the mesenchymal stromal cell secretome.
Liu FD, Tam K, Pishesha N, Poon Z, Van Vliet KJ.
Stem Cell Res Ther. 2018 10 24. 9(1):268. PMID: 30352620
Sortase A: A Model for Transpeptidation and Its Biological Applications.
Pishesha N, Ingram JR, Ploegh HL.
Annu Rev Cell Dev Biol. 2018 10 06. 34:163-188. PMID: 30110557
Enhanced phosphocholine metabolism is essential for terminal erythropoiesis.
Huang NJ, Lin YC, Lin CY, Pishesha N, Lewis CA, Freinkman E, Farquharson C, Millán JL, Lodish H.
Blood. 2018 06 28. 131(26):2955-2966. PMID: 29712634
Targeting Cytokine Therapy to the Pancreatic Tumor Microenvironment Using PD-L1-Specific VHHs.
Dougan M, Ingram JR, Jeong HJ, Mosaheb MM, Bruck PT, Ali L, Pishesha N, Blomberg O, Tyler PM, Servos MM, Rashidian M, Nguyen QD, von Andrian UH, Ploegh HL, Dougan SK.
Cancer Immunol Res. 2018 04. 6(4):389-401. PMID: 29459478
Localized CD47 blockade enhances immunotherapy for murine melanoma.
Ingram JR, Blomberg OS, Sockolosky JT, Ali L, Schmidt FI, Pishesha N, Espinosa C, Dougan SK, Garcia KC, Ploegh HL, Dougan M.
Proc Natl Acad Sci U S A. 2017 09 19. 114(38):10184-10189. PMID: 28874561
Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin.
Huang NJ, Pishesha N, Mukherjee J, Zhang S, Deshycka R, Sudaryo V, Dong M, Shoemaker CB, Lodish HF.
Nat Commun. 2017 09 04. 8(1):423. PMID: 28871080
Site-Specific Protein Labeling via Sortase-Mediated Transpeptidation.
Antos JM, Ingram J, Fang T, Pishesha N, Truttmann MC, Ploegh HL.
Curr Protoc Protein Sci. 2017 08 01. 89:15.3.1-15.3.19. PMID: 28762490
Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease.
Pishesha N, Bilate AM, Wibowo MC, Huang NJ, Li Z, Deshycka R, Bousbaine D, Li H, Patterson HC, Dougan SK, Maruyama T, Lodish HF, Ploegh HL.
Proc Natl Acad Sci U S A. 2017 03 21. 114(12):3157-3162. PMID: 28270614