Pier Francesco Palamara

Cell-free DNA TAPS provides multimodal information for early cancer detection.

Siejka-Zielinska P, Cheng J, Jackson F, Liu Y, Soonawalla Z, Reddy S, Silva M, Puta L, McCain MV, Culver EL, Bekkali N, Schuster-Böckler B, Palamara PF, Mann D, Reeves H, Barnes E, Sivakumar S, Song CX.

Sci Adv. 2021 Sep 03. 7(36):eabh0534. PMID: 34516908

Identity-by-descent detection across 487,409 British samples reveals fine scale population structure and ultra-rare variant associations.

Nait Saada J, Kalantzis G, Shyr D, Cooper F, Robinson M, Gusev A, Palamara PF.

Nat Commun. 2020 11 30. 11(1):6130. PMID: 33257650

Genome-Wide Natural Selection Signatures Are Linked to Genetic Risk of Modern Phenotypes in the Japanese Population.

Yasumizu Y, Sakaue S, Konuma T, Suzuki K, Matsuda K, Murakami Y, Kubo M, Palamara PF, Kamatani Y, Okada Y.

Mol Biol Evol. 2020 05 01. 37(5):1306-1316. PMID: 31957793

Author Correction: Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.

Gazal S, Finucane HK, Furlotte NA, Loh PR, Palamara PF, Liu X, Schoech A, Bulik-Sullivan B, Neale BM, Gusev A, Price AL.

Nat Genet. 2019 Aug. 51(8):1295. PMID: 31273336

Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection.

Schoech AP, Jordan DM, Loh PR, Gazal S, O'Connor LJ, Balick DJ, Palamara PF, Finucane HK, Sunyaev SR, Price AL.

Nat Commun. 2019 02 15. 10(1):790. PMID: 30770844

Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk.

Reshef YA, Finucane HK, Kelley DR, Gusev A, Kotliar D, Ulirsch JC, Hormozdiari F, Nasser J, O'Connor L, van de Geijn B, Loh PR, Grossman SR, Bhatia G, Gazal S, Palamara PF, Pinello L, Patterson N, Adams RP, Price AL.

Nat Genet. 2018 10. 50(10):1483-1493. PMID: 30177862

High-throughput inference of pairwise coalescence times identifies signals of selection and enriched disease heritability.

Palamara PF, Terhorst J, Song YS, Price AL.

Nat Genet. 2018 09. 50(9):1311-1317. PMID: 30104759

Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations.

Loh PR, Genovese G, Handsaker RE, Finucane HK, Reshef YA, Palamara PF, Birmann BM, Talkowski ME, Bakhoum SF, McCarroll SA, Price AL.

Nature. 2018 07. 559(7714):350-355. PMID: 29995854

Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.

Gazal S, Finucane HK, Furlotte NA, Loh PR, Palamara PF, Liu X, Schoech A, Bulik-Sullivan B, Neale BM, Gusev A, Price AL.

Nat Genet. 2017 Oct. 49(10):1421-1427. PMID: 28892061

Reference-based phasing using the Haplotype Reference Consortium panel.

Loh PR, Danecek P, Palamara PF, Fuchsberger C, A Reshef Y, K Finucane H, Schoenherr S, Forer L, McCarthy S, Abecasis GR, Durbin R, L Price A.

Nat Genet. 2016 11. 48(11):1443-1448. PMID: 27694958