Renata L.S. Goncalves

Ubiquinone deficiency drives reverse electron transport to disrupt hepatic metabolic homeostasis in obesity.

Goncalves RLS, Wang ZB, Inouye KE, Lee GY, Fu X, Saksi J, Rosique C, Parlakgul G, Arruda AP, Hui ST, Loperena MC, Burgess SC, Graupera I, Hotamisligil GS.

bioRxiv. 2023 Feb 22. PMID: 36865319

Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H2 O2 production in heart and skeletal muscle mitochondria.

Goncalves RLS, Schlame M, Bartelt A, Brand MD, Hotamisligil GS.

FEBS Lett. 2021 02. 595(3):415-432. PMID: 33112430

TMEM2 Modulates ER Stress in a Non-canonical Manner.

Goncalves RLS, Hotamisligil GS.

Cell Metab. 2019 12 03. 30(6):999-1001. PMID: 31801059

The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production.

Goncalves RLS, Watson MA, Wong HS, Orr AL, Brand MD.

Redox Biol. 2020 01. 28:101341. PMID: 31627168

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.

Bartelt A, Widenmaier SB, Schlein C, Johann K, Goncalves RLS, Eguchi K, Fischer AW, Parlakgül G, Snyder NA, Nguyen TB, Bruns OT, Franke D, Bawendi MG, Lynes MD, Leiria LO, Tseng YH, Inouye KE, Arruda AP, Hotamisligil GS.

Nat Med. 2018 03. 24(3):292-303. PMID: 29400713

Defective STIM-mediated store operated Ca2+ entry in hepatocytes leads to metabolic dysfunction in obesity.

Arruda AP, Pers BM, Parlakgul G, Güney E, Goh T, Cagampan E, Lee GY, Goncalves RL, Hotamisligil GS.

Elife. 2017 12 15. 6. PMID: 29243589

Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling.

Weir HJ, Yao P, Huynh FK, Escoubas CC, Goncalves RL, Burkewitz K, Laboy R, Hirschey MD, Mair WB.

Cell Metab. 2017 Dec 05. 26(6):884-896.e5. PMID: 29107506

Catalase protects Aedes aegypti from oxidative stress and increases midgut infection prevalence of Dengue but not Zika.

Oliveira JHM, Talyuli OAC, Goncalves RLS, Paiva-Silva GO, Sorgine MHF, Alvarenga PH, Oliveira PL.

PLoS Negl Trop Dis. 2017 04. 11(4):e0005525. PMID: 28379952

Resistance training to improve type 2 diabetes: working toward a prescription for the future.

Pesta DH, Goncalves RLS, Madiraju AK, Strasser B, Sparks LM.

Nutr Metab (Lond). 2017. 14:24. PMID: 28270856

Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.

Brand MD, Goncalves RL, Orr AL, Vargas L, Gerencser AA, Borch Jensen M, Wang YT, Melov S, Turk CN, Matzen JT, Dardov VJ, Petrassi HM, Meeusen SL, Perevoshchikova IV, Jasper H, Brookes PS, Ainscow EK.

Cell Metab. 2016 10 11. 24(4):582-592. PMID: 27667666