Rory D Kirchner

Identification of Novel Alzheimer's Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data.

Prokopenko D, Hecker J, Kirchner R, Chapman BA, Hoffman O, Mullin K, Hide W, Bertram L, Laird N, DeMeo DL, Lange C, Tanzi RE.

Sci Rep. 2020 03 19. 10(1):5029. PMID: 32193444

A cell atlas of the adult Drosophila midgut.

Hung RJ, Hu Y, Kirchner R, Liu Y, Xu C, Comjean A, Tattikota SG, Li F, Song W, Ho Sui S, Perrimon N.

Proc Natl Acad Sci U S A. 2020 01 21. 117(3):1514-1523. PMID: 31915294

Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9.

Oh HS, Neuhausser WM, Eggan P, Angelova M, Kirchner R, Eggan KC, Knipe DM.

Elife. 2019 12 02. 8. PMID: 31789594

Supporting Single Cell RNA-seq Analysis at Harvard - A Community Approach.

Sui SH, Kirchner R, Steinbaugh M, Boswell S, Piper M, Barrera V, Pantano L, Khetani R, Mistry M, Rutherford K, Hutchinson J.

J Biomol Tech. 2019 Dec. 30(Suppl):S39. PMID: 31896961

ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair.

Klim JR, Williams LA, Limone F, Guerra San Juan I, Davis-Dusenbery BN, Mordes DA, Burberry A, Steinbaugh MJ, Gamage KK, Kirchner R, Moccia R, Cassel SH, Chen K, Wainger BJ, Woolf CJ, Eggan K.

Nat Neurosci. 2019 02. 22(2):167-179. PMID: 30643292

Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex.

Poulopoulos A, Murphy AJ, Ozkan A, Davis P, Hatch J, Kirchner R, Macklis JD.

Nature. 2019 01. 565(7739):356-360. PMID: 30626971

Single-cell transcriptomics of the developing lateral geniculate nucleus reveals insights into circuit assembly and refinement.

Kalish BT, Cheadle L, Hrvatin S, Nagy MA, Rivera S, Crow M, Gillis J, Kirchner R, Greenberg ME.

Proc Natl Acad Sci U S A. 2018 01 30. 115(5):E1051-E1060. PMID: 29343640

Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment.

Li A, Hooli B, Mullin K, Tate RE, Bubnys A, Kirchner R, Chapman B, Hofmann O, Hide W, Tanzi RE.

Hum Mol Genet. 2017 04 15. 26(8):1472-1482. PMID: 28186563

In Vitro Effects of Lead on Gene Expression in Neural Stem Cells and Associations between Up-regulated Genes and Cognitive Scores in Children.

Wagner PJ, Park HR, Wang Z, Kirchner R, Wei Y, Su L, Stanfield K, Guilarte TR, Wright RO, Christiani DC, Lu Q.

Environ Health Perspect. 2017 04. 125(4):721-729. PMID: 27562236

High-throughput functional comparison of promoter and enhancer activities.

Nguyen TA, Jones RD, Snavely AR, Pfenning AR, Kirchner R, Hemberg M, Gray JM.

Genome Res. 2016 08. 26(8):1023-33. PMID: 27311442