Steffen Ventz

Leveraging external data in the design and analysis of clinical trials in neuro-oncology.

Rahman R, Ventz S, McDunn J, Louv B, Reyes-Rivera I, Polley MC, Merchant F, Abrey LE, Allen JE, Aguilar LK, Aguilar-Cordova E, Arons D, Tanner K, Bagley S, Khasraw M, Cloughesy T, Wen PY, Alexander BM, Trippa L.

Lancet Oncol. 2021 Oct. 22(10):e456-e465. PMID: 34592195

Integration of survival data from multiple studies.

Ventz S, Mazumder R, Trippa L.

Biometrics. 2021 Jun 30. PMID: 34190337

KMDATA: a curated database of reconstructed individual patient-level data from 153 oncology clinical trials.

Fell G, Redd RA, Vanderbeek AM, Rahman R, Louv B, McDunn J, Arfè A, Alexander BM, Ventz S, Trippa L.

Database (Oxford). 2021 06 26. 2021. PMID: 34169314

The Use of External Control Data for Predictions and Futility Interim Analyses in Clinical Trials.

Ventz S, Comment L, Louv B, Rahman R, Wen PY, Alexander BM, Trippa L.

Neuro Oncol. 2021 Jun 09. PMID: 34106270

Assessment of Simulated SARS-CoV-2 Infection and Mortality Risk Associated With Radiation Therapy Among Patients in 8 Randomized Clinical Trials.

Tabrizi S, Trippa L, Cagney D, Aizer AA, Tanguturi S, Ventz S, Fell G, Bellon JR, Mamon H, Nguyen PL, D'Amico AV, Haas-Kogan D, Alexander BM, Rahman R.

JAMA Netw Open. 2021 03 01. 4(3):e213304. PMID: 33779742

The effects of releasing early results from ongoing clinical trials.

Ventz S, Bacallado S, Rahman R, Tolaney S, Schoenfeld JD, Alexander BM, Trippa L.

Nat Commun. 2021 02 05. 12(1):801. PMID: 33547324

TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes.

Tung NM, Robson ME, Ventz S, Santa-Maria CA, Nanda R, Marcom PK, Shah PD, Ballinger TJ, Yang ES, Vinayak S, Melisko M, Brufsky A, DeMeo M, Jenkins C, Domchek S, D'Andrea A, Lin NU, Hughes ME, Carey LA, Wagle N, Wulf GM, Krop IE, Wolff AC, Winer EP, Garber JE.

J Clin Oncol. 2020 12 20. 38(36):4274-4282. PMID: 33119476

Shared and Usable Data From Phase 1 Oncology Trials-An Unmet Need.

Arfè A, Ventz S, Trippa L.

JAMA Oncol. 2020 07 01. 6(7):980-981. PMID: 32496530

A Quantitative Framework for Modeling COVID-19 Risk During Adjuvant Therapy Using Published Randomized Trials of Glioblastoma in the Elderly.

Tabrizi S, Trippa L, Cagney D, Tanguturi S, Ventz S, Fell G, Wen PY, Alexander BM, Rahman R.

Neuro Oncol. 2020 Apr 27. PMID: 32339235

To randomize, or not to randomize, that is the question: using data from prior clinical trials to guide future designs.

Vanderbeek AM, Ventz S, Rahman R, Fell G, Cloughesy TF, Wen PY, Trippa L, Alexander BM.

Neuro Oncol. 2019 10 09. 21(10):1239-1249. PMID: 31155679