Steven Gazal

SNP-to-gene linking strategies reveal contributions of enhancer-related and candidate master-regulator genes to autoimmune disease.

Dey KK, Gazal S, van de Geijn B, Kim SS, Nasser J, Engreitz JM, Price AL.

Cell Genom. 2022 Jul 13. 2(7). PMID: 35873673

Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity.

Gazal S, Weissbrod O, Hormozdiari F, Dey KK, Nasser J, Jagadeesh KA, Weiner DJ, Shi H, Fulco CP, O'Connor LJ, Pasaniuc B, Engreitz JM, Price AL.

Nat Genet. 2022 06. 54(6):827-836. PMID: 35668300

Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores.

Weissbrod O, Kanai M, Shi H, Gazal S, Peyrot WJ, Khera AV, Okada Y, Martin AR, Finucane HK, Price AL.

Nat Genet. 2022 04. 54(4):450-458. PMID: 35393596

Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes.

Burch KS, Hou K, Ding Y, Wang Y, Gazal S, Shi H, Pasaniuc B.

Am J Hum Genet. 2022 04 07. 109(4):692-709. PMID: 35271803

Partitioning gene-mediated disease heritability without eQTLs.

Weiner DJ, Gazal S, Robinson EB, O'Connor LJ.

Am J Hum Genet. 2022 03 03. 109(3):405-416. PMID: 35143757

Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics.

Jagadeesh KA, Dey KK, Montoro DT, Mohan R, Gazal S, Engreitz JM, Xavier RJ, Price AL, Regev A.

bioRxiv. 2021 Nov 23. PMID: 34845454

Incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets.

Márquez-Luna C, Gazal S, Loh PR, Kim SS, Furlotte N, Auton A, Price AL.

Nat Commun. 2021 10 18. 12(1):6052. PMID: 34663819

An integrated approach to identify environmental modulators of genetic risk factors for complex traits.

Balliu B, Carcamo-Orive I, Gloudemans MJ, Nachun DC, Durrant MG, Gazal S, Park CY, Knowles DA, Wabitsch M, Quertermous T, Knowles JW, Montgomery SB.

Am J Hum Genet. 2021 10 07. 108(10):1866-1879. PMID: 34582792

Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations.

Luo Y, Li X, Wang X, Gazal S, Mercader JM, Neale BM, Florez JC, Auton A, Price AL, Finucane HK, Raychaudhuri S.

Hum Mol Genet. 2021 07 28. 30(16):1521-1534. PMID: 33987664

COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.

Delorey TM, Ziegler CGK, Heimberg G, Normand R, Yang Y, Segerstolpe Å, Abbondanza D, Fleming SJ, Subramanian A, Montoro DT, Jagadeesh KA, Dey KK, Sen P, Slyper M, Pita-Juárez YH, Phillips D, Biermann J, Bloom-Ackermann Z, Barkas N, Ganna A, Gomez J, Melms JC, Katsyv I, Normandin E, Naderi P, Popov YV, Raju SS, Niezen S, Tsai LT, Siddle KJ, Sud M, Tran VM, Vellarikkal SK, Wang Y, Amir-Zilberstein L, Atri DS, Beechem J, Brook OR, Chen J, Divakar P, Dorceus P, Engreitz JM, Essene A, Fitzgerald DM, Fropf R, Gazal S, Gould J, Grzyb J, Harvey T, Hecht J, Hether T, Jané-Valbuena J, Leney-Greene M, Ma H, McCabe C, McLoughlin DE, Miller EM, Muus C, Niemi M, Padera R, Pan L, Pant D, Pe'er C, Pfiffner-Borges J, Pinto CJ, Plaisted J, Reeves J, Ross M, Rudy M, Rueckert EH, Siciliano M, Sturm A, Todres E, Waghray A, Warren S, Zhang S, Zollinger DR, Cosimi L, Gupta RM, Hacohen N, Hibshoosh H, Hide W, Price AL, Rajagopal J, Tata PR, Riedel S, Szabo G, Tickle TL, Ellinor PT, Hung D, Sabeti PC, Novak R, Rogers R, Ingber DE, Jiang ZG, Juric D, Babadi M, Farhi SL, Izar B, Stone JR, Vlachos IS, Solomon IH, Ashenberg O, Porter CBM, Li B, Shalek AK, Villani AC, Rozenblatt-Rosen O, Regev A.

Nature. 2021 07. 595(7865):107-113. PMID: 33915569