Thomas Stephen Morley

Adipocyte mesenchymal transition contributes to mammary tumor progression.

Zhu Q, Zhu Y, Hepler C, Zhang Q, Park J, Gliniak C, Henry GH, Crewe C, Bu D, Zhang Z, Zhao S, Morley T, Li N, Kim DS, Strand D, Deng Y, Robino JJ, Varlamov O, Gordillo R, Kolonin MG, Kusminski CM, Gupta RK, Scherer PE.

Cell Rep. 2022 09 13. 40(11):111362. PMID: 36103820

Characterizing Lymphangiogenesis and Concurrent Inflammation in Adipose Tissue in Response to VEGF-D.

Chakraborty A, Scogin CK, Rizwan K, Morley TS, Rutkowski JM.

Front Physiol. 2020. 11:363. PMID: 32390866

A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive ß-Cell Hyperplasia.

Kusminski CM, Ghaben AL, Morley TS, Samms RJ, Adams AC, An Y, Johnson JA, Joffin N, Onodera T, Crewe C, Holland WL, Gordillo R, Scherer PE.

Diabetes. 2020 03. 69(3):313-330. PMID: 31882562

Vascular Endothelial Growth Factor-D (VEGF-D) Overexpression and Lymphatic Expansion in Murine Adipose Tissue Improves Metabolism in Obesity.

Chakraborty A, Barajas S, Lammoglia GM, Reyna AJ, Morley TS, Johnson JA, Scherer PE, Rutkowski JM.

Am J Pathol. 2019 04. 189(4):924-939. PMID: 30878136

Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice.

Xia JY, Sun K, Hepler C, Ghaben AL, Gupta RK, An YA, Holland WL, Morley TS, Adams AC, Gordillo R, Kusminski CM, Scherer PE.

Diabetologia. 2018 04. 61(4):932-941. PMID: 29224189

Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice.

Hepler C, Shao M, Xia JY, Ghaben AL, Pearson MJ, Vishvanath L, Sharma AX, Morley TS, Holland WL, Gupta RK.

Elife. 2017 07 19. 6. PMID: 28722653

Pdgfrß+ Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult Mice.

Vishvanath L, MacPherson KA, Hepler C, Wang QA, Shao M, Spurgin SB, Wang MY, Kusminski CM, Morley TS, Gupta RK.

Cell Metab. 2016 Feb 09. 23(2):350-9. PMID: 26626462

Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements.

Morley TS, Xia JY, Scherer PE.

Nat Commun. 2015 Aug 05. 6:7906. PMID: 26243466

Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes ß-cell regeneration.

Ye R, Holland WL, Gordillo R, Wang M, Wang QA, Shao M, Morley TS, Gupta RK, Stahl A, Scherer PE.

Elife. 2014 Oct 23. 3. PMID: 25339419

Obesity and cancer--mechanisms underlying tumour progression and recurrence.

Park J, Morley TS, Kim M, Clegg DJ, Scherer PE.

Nat Rev Endocrinol. 2014 Aug. 10(8):455-465. PMID: 24935119