My laboratory studies molecular mechanisms underlying complex gene-environment interactions in multigenic human diseases such as asthma and neurodegeneration, focusing in part on the emerging role of extracellular vesicles in disease pathogenesis, prevention, and therapeutics. Research in my laboratory is supported by multiple NIH R01 grants and a Program Project grant as well as gifts from private companies and foundations.
Here are some examples of our recent work.
A versatile vessel for next-gen therapeutics
GSDMB-induced pyroptosis – A root cause of asthma?
How does lead harm neurodevelopment?