Uganda

Governing Agencies and Ethics Review Structure

Institutional Review Committees (IRC) are responsible for the review and approval of initial and continuing review protocols taking place in Uganda. The IRC is also responsible for the protection and welfare of human research participants. IRCs operating in Uganda must receive accreditation from the Uganda National Council for Science and Technology (UNCST).

Research councils

  • Uganda National Council for Science and Technology (UNCST)
  • National Bio-safety Committee (NBC)
  • Institutional Review Committee Accreditation (AC)
  • National HIV/AIDS Research Committee (NARC)
  • Uganda National Academy of Sciences
  • Uganda National Health Research Organization (UNHRO)
  • The Uganda Virus Research Institute (UVRI), Entebbe
  • National Chemotherapeutic Council

Useful Documents

Points to Consider – Investigators

Besides the UNCST and IRCs, there are other committees that are involved in the oversight of research projects. These committees include:

  • National Drug Authority (NDA): The NDA may issue a certificate to an investigator for the purpose of carrying out clinical trials
  • Scientific Committees (SCs) : SCs are occasionally set up within institutions as an internal review mechanism. Where such committees exist, they should approve the research protocol prior to submission to an IRC.
  • Data and Safety Monitoring Board (DSMB) : An independent group of experts established by the study sponsors to review safety data during a clinical trial.
  • Community Advisory Boards (CABs) : CABs are established by the research investigators. They are important for facilitating dialogue between community members, study volunteers and researchers.
  • Institutional Bio-safety Committees (IBC) : IBCs are established by institutions that are involved in research with potentially hazardous substances of a physical, chemical, biological, or any other nature. Any institution involved in or planning to conduct research with potentially hazardous substances are required to set up or designate a competent IBC

Local Research Institutions