Publications

Publications

1.     Fortune SM, Solache A, Jaeger A, Hill PJ, Belisle JT, Bloom BR, Rubin EJ, and Ernst JD. Mycobacterium tuberculosis inhibits macrophage responses to IFN-gamma through myeloid differentiation factor 88-dependent and -independent mechanisms.  J Immunol. 2004 May 15;172(10):6272-80. PMID: 15128816.

2.     Fortune SM, Jaeger A, Sarracino DA, Chase MR, Sassetti CM, Sherman DR, Bloom BR and Rubin EJ.  Mutually-dependent secretion of proteins required for mycobacterial virulence.   PNAS, 2005 Jul 26;102(30):10676-81.  PMCID: PMC1176248.

3.     Joshi S, Pandey AK, Capite N, Fortune SM, Rubin EJ, Sassetti CM.   Characterization of Mycobacterial Virulence Genes through Genetic Interaction Mapping.   PNAS, 2006 Aug 1;103(31):11760-5.  PMCID: PMC1544243.

4.     Hett EC, Chao MC, Steyn AJ, Fortune SM, Deng LL and Rubin EJ.  A partner for the resuscitation promoting factors of Mycobacterium tuberculosis.  Mol Micro., 2007, Oct 6(3); 66:658-668. PMID: 17919286.

5.     Woodworth, JS, Fortune SM and Behar SM.  Bacterial protein secretion is required for priming of CD8+ T cells specific for the Mycobacterium tuberculosis antigen CFP10.  Infect Immun, 2008, Jul 7; 76(9) 4199-4205. PMCID: PMC2519428.

6.     Pandey AK, Yang Y, Jiang Z, Fortune SM, Coulombe F, Behr MA, Fitzgerald KA, Sassetti CM and Kelliher MA.  NOD2, RIP2 and IRF5 Play a Critical Role in the Type I Interferon Response to Mycobacterium tuberculosis.  PLOSPathogens, 2009, Jul;5(7):e1000500. PMCID: PMC269812.

7.     Divangahi M, Chen M, Gan H, Desjardins D, Hickman TT, Lee DM, Fortune S, Behar SM, Remold HG.  Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair.  Nat Immunol. 2009 Aug;10(8):899-906.  PMCID: PMC2730354.

8.     Siegrist MS, Unnikrishnan M, McConnell MJ, Borowsky M, Cheng TY, Siddiqi N, Fortune SM, Moody DB, Rubin EJ.  Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition.  PNAS, 2009 Nov 3;106(44):18792-7. Epub 2009 Oct 21.  PMCID: PMC2774023.

9.     Ioerger TR, Feng Y, Ganesula K, Chen X, Dobos KM, Fortune S, Jacobs WR Jr, Mizrahi V, Parish T, Rubin E, Sassetti C, Sacchettini JC. Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories. J Bacteriol. 2010 Jul;192(14):3645-53. Epub 2010 May 14. PMCID: PMC2897344.

10.  Garces A, Atmakuri K, Chase MR, Woodworth JS, Krastins B, Rothchild AC, Ramsdell TL, Lopez MF, Behar SM, Sarracino DA, Fortune SMEspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity.  PLoSPathogens. 2010 Jun 24;6(6):e1000957. PMCID: PMC2891827

11.  Millington KA, Fortune SM, Low J, Garces A, Hingley-Wilson SM, Wickremasignhe M, Kon OM, Lalvani A. EspC is a highly immunodominant ESX-1-dependent secreted antigen specific for M. tuberculosis infection.   PNAS, 2011 Apr 5;108(14):5730-5. PMCID: PMC3078386

12.  Ford CB, Lin PL, Chase MR, Shah RR, Iartchouk O, Galagan JE, Ioerger TR, Mohaideen N, Sacchettini J, Lipsitch M, Flynn JL and Fortune SM. Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection. Nat Genet. 2011 May;43(5):482-6. Epub 2011 Apr 24.  PMID: 21516081 [PubMed - in process].

13.  Woodworth JS, Shin D, Volman M, Nunes-Alves C, Fortune SM, Behar SM.   Mycobacterium tuberculosis Directs Immunofocusing of CD8+ T Cell Responses Despite Vaccination. J Immunol. 2011 Feb 1:186(3):1627-37. Epub 2010 Dec 22.

14.  Sille F, Martin C, Jayaraman P, Rothchild A, Fortune S, Besra G, Behar S, Boes M.  Requirement for Invariant chain in macrophages for Mycobacterium tuberculosis replication and CD1d antigen presentation. Infect Immun, accepted for publication.