Xavier Trepat

Visiting Scientist

Department of Environmental Health

Department of Environmental Health

655 Huntington Avenue
Room 1307
Boston, MA 02115


Trepat X, Wasserman MR, Angelini TE, Millet E, Weitz DA, Butler JP, Fredberg JJ. Physical forces during collective cell migration. Nature Phys 5, 426 (2009).

Zhou E, Trepat X, Park CY, Lenormand G, Oliver M, Mijailovich SM, Hardin C, Weitz DA, Butler JP, Fredberg JJ. Universal behavior of the osmotically compressed cell and its analogy to the colloidal glass transition. PNAS 106, 10632 (2009).

An SS, Kim J, Ahn K, Trepat X, Drake KJ, Kumar S, Ling G, Purington C, Rangasamy T, Kensler TW, Mitzner W, Fredberg JJ, Biswal S. Cell stiffness, contractile stress and the role of extracellular matrix. Biochem Biophys Res Commun 382 (4), 697 (2009).

Krishnan R, Park CY, Lin YC, Mead J, Jaspers RT, Trepat X, Lenormand G, Tambe D, Smolensky AV, Knoll AH, Butler JP, Fredberg JJ. Reinforcement versus fluidization in cytoskeletal mechanoresponsiveness. PLoS ONE 4 (5), e5486 (2009).

Krishnan R, Trepat X, Nguyen TT, Lenormand G, Oliver M, Fredberg JJ. Airway smooth muscle and bronchospasm: Fluctuating, fluidizing, freezing. Respir Physiol Neurobiol 163 (1-3), 17 (2008).

Trepat X, Farre R. Alveolar permeability and stretch: Too far, too fast. Eur Respir J 32 (4), 826 (2008).

Trepat X, Lenormand G, Fredberg JJ. Universality in cell mechanics. Soft Matter 4, 1750 (2008).

Bursac P, Fabry B, Trepat X, Lenormand G, Butler JP, Wang N, Fredberg JJ, An SS. Cytoskeleton dynamics: Fluctuations within the network. Biochem Biophys Res Commun 355 (2), 324 (2007).

Trepat X, Deng L, An SS, Navajas D, Tschumperlin DJ, Gerthoffer WT, Butler JP, Fredberg JJ. Universal physical responses to stretch in the living cell. Nature 447 (7144), 592 (2007).

An SS, Fabry B, Trepat X, Wang N, Fredberg JJ. Do biophysical properties of the airway smooth muscle in culture predict airway hyperresponsiveness? Am J Respir Cell Mol Biol 35 (1), 55 (2006).

Deng L, Trepat X, Butler JP, Millet E, Morgan KG, Weitz DA, Fredberg JJ. Fast and slow dynamics of the cytoskeleton. Nature Mater 5 (8), 636 (2006).

Trepat X, Puig F, Gavara N, Fredberg JJ, Farre R, Navajas D. Effect of stretch on structural integrity and micromechanics of human alveolar epithelial cell monolayers exposed to thrombin. Am J Physiol Lung Cell Mol Physiol 290 (6), L1104 (2006).

Trepat X, Grabulosa M, Buscemi L, Rico F, Farre R, Navajas D. Thrombin and histamine induce stiffening of alveolar epithelial cells. J Appl Physiol 98 (4), 1567 (2005).

Rigau J, Farre R, Trepat X, Shusterman D, Navajas D. Oscillometric assessment of airway obstruction in a mechanical model of vocal cord dysfunction. J Biomech 37 (1), 37 (2004).

Trepat X, Grabulosa M, Puig F, Maksym GN, Navajas D, Farre R. Viscoelasticity of human alveolar epithelial cells subjected to stretch. Am J Physiol Lung Cell Mol Physiol 287 (5), L1025 (2004).

Alcaraz J, Buscemi L, Grabulosa M, Trepat X, Fabry B, Farre R, Navajas D. Microrheology of human lung epithelial cells measured by atomic force microscopy. Biophys J 84 (3), 2071 (2003).

Trepat X, Grabulosa M, Buscemi L, Rico F, Fabry B, Fredberg JJ, Farre R. Oscillatory magnetic tweezers based on ferromagnetic beads and simple coaxial coils. Rev Sci Instrum 74 (9), 4012 (2003).

Farre R, Montserrat JM, Rigau J, Trepat X, Pinto P, Navajas D. Response of automatic continuous positive airway pressure devices to different sleep breathing patterns: A bench study. Am J Respir Crit Care Med 166 (4), 469 (2002).


Trepat Group at the University of Barcelona / Institute for Bioengineering of Catalonia