Alumni

Predoctoral Alumni

 

Glen Mcgee (2014-in training)

Sarah Peskoe (2013-2017)

Abigail Sloan (2014-in training)

Thomas C. Madsen (2014-in training)

Ina Jazic (2013-2018)

David (Valken Leduc) Tucker (2012- )

Current Position: Marketing Analyst, backcountry.com

 Ryan Sun (2012-2017)

Current Position: Research Fellow, Biostatistics, Harvard T.H. Chan School of Public Health

Daniel Schlauch (2012-2017)

Current Position: Principal Biostatistician, Genospace

Publications while in training include:

  • Howe EA, Sinha R, Schlauch D, Quackenbush J. RNA-Seq analysis in MeV. Bioinformatics. 2011 Nov 15;27(22):3209-10. doi: 10.1093/bioinformatics/btr490. Epub 2011 Oct 5. PubMed PMID: 21976420; PubMed Central PMCID: PMC3208390.

Kevin J. Galinsky (2012-2017)

Current Position: Senior Statistician, Takeda Oncology

Publications while in training include:

  • Sharma P, Wollenberg K, Sellers M, Zainabadi K, Galinsky K, Moss E, Nguitragool W, Neafsey D, Desai SA. An epigenetic antimalarial resistance mechanism involving parasite genes linked to nutrient uptake. J Biol Chem. 2013 Jul 5;288(27):19429-40. doi: 10.1074/jbc.M113.468371. Epub 2013 May 28. PubMed PMID: 23720749; PubMed Central PMCID: PMC3707646.
  • Lukens AK, Heidebrecht RW Jr, Mulrooney C, Beaudoin JA, Comer E, Duvall JR, Fitzgerald ME, Masi D, Galinsky K, Scherer CA, Palmer M, Munoz B, Foley M,Schreiber SL, Wiegand RC, Wirth DF. Diversity- Oriented Synthesis Probe Targets Plasmodium falciparum Cytochrome b Ubiquinone Reduction Site and Synergizes With Oxidation Site Inhibitors. J Infect Dis. 2014 Oct 21. pii: jiu565. [Epub ahead of print] PubMed PMID: 25336726. PMCID: PMC4354981
  • Galinsky K, Valim C, Salmier A, de Thoisy B, Musset L, Legrand E, Faust A, Baniecki ML, Ndiaye D, Daniels RF, Hartl DL, Sabeti PC, Wirth DF, Volkman SK, Neafsey DE. COIL: a methodology for evaluating malarial complexity of infection using likelihood from single nucleotide polymorphism data. Malar J. 2015 Jan 19;14(1):4. [Epub ahead of print] PubMed PMID: 25599890. PMC journal-in process.
  • Baniecki ML, Faust AL, Schaffner SF, Park DJ, Galinsky K, Daniels RF, Hamilton E, Ferreira MU, Karunaweera ND, Serre D, Zimmerman PA, Sá JM, Wellems TE, Musset L, Legrand E, Melnikov A, Neafsey DE, Volkman SK, Wirth DF, Sabeti PC. Development of a Single Nucleotide Polymorphism Barcode to Genotype Plasmodium vivax Infections. PLoS Negl Trop Dis. 2015 Mar 17;9(3):e0003539. doi: 10.1371/journal.pntd.0003539. eCollection 2015. PMCID:PMC4362761
  • Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA, Patel V, Clish CB, Sullivan Jr.WJ, Zhou H, Bopp SE, Schimmel P, Lindquist S, Clardy J, Mota MM, Keller TL, Whitman M, Wiest O, Wirth DF, Mazitschek R. Plasmodium Prolyl-tRNA Synthetase: A Druggable Next Generation Dual-Stage Target for Malaria Elimination. Science Translational Medicine. 2015 May. In press.

Sixing Chen (2012-2017)

Current Position: Postdoctoral Research Fellow, Department of Biostatistics, Harvard T.H. Chan School of Public Health

Florence Hiu-Ling Yong (2010-2015)

Current Position: Associate Director, Biostatistics Pfizer, Inc.

Publications while in training include:

  • Yong, F., Cai, T., Tian, L., and Wei, LJ. (2013), “Making valid inferences for prediction of survival via Cox’s working models with baseline covariates.” Published in Klein, J., van Houwelingen, H., Ibrahim, J. and T.H., S., ed. (2013), as Chapter 13 Classical Model Selection, Handbook of Survival Analysis, CRC Press. July 2013.
  • Yong, F.; Tian, Lu; Yu, Sheng; Cai, Tianxi; and Wei, L. J., “Predicting the Future Subject’s Outcome via an Optimal Stratification Procedure with Baseline Information” (July 2014). Harvard University Biostatistics Working Paper Series. Working Paper 173. Submitted to Biometrika.
  • Yong, F.; Tian, Lu; and Wei, L. J., “Identifying subgroups with successive average treatment effect via constrained optimization in stratified medicine.” To be submitted
  • Communication piece related to this research and big data to raise awareness:
Yong F. “An Analytic Approach to Risk and Intervention.” Harvard Colloquy Magazine [Internet]. 2014;(Spring 2014). The Graduate School of Arts and Sciences, Harvard University publication.

Adam J. Sullivan (2010-2015)

Current Position: Assistant Professor, Department of Biostatistics, Brown University

Publications while in training include:

  • Tseng YD, Krishnan MS, Sullivan AJ, Jones JA, Chow E, Balboni TA. How radiation oncologists evaluate and incorporate life expectancy estimates into the treatment of palliative cancer patients: a survey-based study. Int J Radiat Oncol Biol Phys. (comment) 2013 Nov 1;87(3):471-8. doi: 10.1016/j.ijrobp.2013.06.2046. PubMed PMID: 24074920. PMCID in process (NIHMSID 689510).
  • Tseng YD, Krishnan MS, Jones JA, Sullivan AJ, Gorman D, Taylor A, Pacold M, Kalinowski B, Mamon HJ, Abrahm J, Balboni TA. Supportive and palliative radiation oncology service: impact of a dedicated service on palliative cancer care. Pract Radiat Oncol. 2014 Jul-Aug;4(4):247-53. doi: 10.1016/j.prro.2013.09.005. Epub 2013 Nov 20. PubMed PMID: 25012833. PMCID in process (NIHMSID 689522).
  • Epstein-Peterson ZD, Sullivan AJ, Enzinger AC, Trevino KM, Zollfrank AA, Balboni MJ, VanderWeele TJ, Balboni TA. Examining Forms of Spiritual Care Provided in the Advanced Cancer Setting. Am J Hosp Palliat Care. 2014 Jul 8. pii: 1049909114540318. [Epub ahead of print] PubMed PMID: 25005589. PMCID in process (NIHMSID 689523).
  • Epstein-Peterson ZD, Sullivan A, Krishnan M, Chen JT, Ferrone M, Ready J,Baldini EH, Balboni T. Postoperative radiation therapy for osseous metastasis: Outcomes and predictors of local failure. Pract Radiat Oncol. 2015 Apr 6. pii: S1879-8500(15)00069-7. doi: 10.1016/j.prro.2015.02.006. [Epub ahead of print] PubMed PMID: 25858770.
  • Sullivan, A.J., VanderWeele, T.J., “Sensitivity Analysis for Unmeasured Confounding in Linear Structural Equation Models”, Statistics in medicine, (Under Review).

Jaclyn A. Scholl McTague (2010-2012)

Current Position: Senior Statistician, Prosoft Clinical

Ritesh Ramchandani (2010-2015)

Current Position: Research Associate, Center for Biostatistics in Aids Research, Harvard T. H. Chan School of Public Health

Publications while in training include:

  • Tomasetti C, Kantarjian HM, Ramchandani R, Jabbour E, Quintas-Cardama A, Parmigiani G and Cortes JE. The Average Baseline BCR-ABL Levels Are Significantly Higher in Patients with Resistance to Dasatinib As First-Line Treatment for Early Chronic Phase Chronic Myeloid Leukemia. Blood. [Meeting Abstract]. 2012 Nov;120(21):1.
  • Sprague BL, Trentham-Dietz A, Gangnon RE, Ramchandani R, Hampton JM, Robert SA, Remington PL, Newcomb PA. Socioeconomic status and survival after an invasive breast cancer diagnosis. Cancer. 2011 Apr 1;117(7):1542-51. doi: 10.1002/cncr.25589. Epub 2010 Nov 8. PubMed PMID: 21425155; PubMed Central PMCID: PMC3116955.
  • Strasser-Weippl K, Ramchandani R, Fan L, Li J, Hurlbert M, Finkelstein D, Shao ZM, Goss PE. Pregnancy- associated breast cancer in women from Shanghai: risk and prognosis. Breast Cancer Res Treat. 2015 Jan;149(1):255-61. doi: 10.1007/s10549-014-3219-9. Epub 2014 Dec 14. PubMed PMID: 25504083. PMCID in Process.
  • Ramchandani R, Finkelstein DM, Schoenfeld DA. A model-informed rank test for right-censored data with intermediate states. Stat Med. 2015 Jan 13. doi: 10.1002/sim.6417. [Epub ahead of print] PMCID:PMC4390437

Ian Barnett (2010-2014)

Current Position: Assistant Professor, Department of Biostatistics and Epidemiology, University of Pennsylvania

Publications while in training include:

  • Barnett IJ, Lee S, Lin X. Detecting rare variant effects using extreme phenotype sampling in sequencing association studies. Genet Epidemiol. 2013 Feb;37(2):142-51. doi: 10.1002/gepi.21699. Epub 2012 Nov 26. PubMed PMID: 23184518; PubMed Central PMCID: PMC3601902.
  • Fan T, Fang SC, Cavallari JM, Barnett IJ, Wang Z, Su L, Byun HM, Lin X, Baccarelli AA, Christiani DC. Heart rate variability and DNA methylation levels are altered after short-term metal fume exposure among occupational welders: a repeated-measures panel study. BMC Public Health. 2014 Dec 16;14:1279. doi: 10.1186/1471-2458-14-1279. PubMed PMID: 25512264; PubMed Central PMCID: PMC4302115.
  • Barnett IJ, Lin X. Analytic P-value calculation for the higher criticism test in finite d Biometrika. 2014;101(4):964-970. PMCID: PMC4350786

Christina McIntosh (2009-2017)

Current Position: Biostatistician, Shire Pharmaceuticals

Publications while in training include:

  • McIntosh and, W. Yip, N. Laird. “Analyzing Pedigrees for Association Analysis.” Provisionally Accepted to Human Heredity (under revision).
  • McIntosh and G. Parmigiani “Cancer Risk in the Nordic Twin Studies of Cancer.” In Preparation.

Lauren M. Kunz (2009-2015)

Current Position: Statistician, Office of Biostatistics, Research National Institutes of Health / National Heart, Lung, and Blood Institute

Publications while in training include:

  • Grotmol T, Bray F, Holte H, Haugen M, Kunz L, Tretli S, Aalen OO, Moger TA. Frailty modeling of the bimodal age-incidence of Hodgkin lymphoma in the Nordic countries. Cancer Epidemiol Biomarkers Prev. 2011 Jul;20(7):1350-7. doi: 10.1158/1055-9965.EPI-10-1014. Epub 2011 May 10. PubMed PMID: 21558495. (not funded by NIH)
  • Kunz LM, Yeh RW, Normand SL. Comparative effectiveness research: does one size fit all? Stat Med. 2012 Nov 10;31(25):3062-5; discussion 3066-7. doi: 10.1002/sim.5482. Epub 2012 Jul 16. PubMed PMID: 22806612 (Commentary).
  • Pettersson A, Graff RE, Bauer SR, Pitt MJ, Lis RT, Stack EC, Martin NE, Kunz L, Penney KL, Ligon AH, Suppan C, Flavin R, Sesso HD, Rider JR, Sweeney C, Stampfer MJ, Fiorentino M, Kantoff PW, Sanda MG, Giovannucci EL, Ding EL, Loda M, Mucci LA. The TMPRSS2:ERG rearrangement, ERG expression, and prostate cancer outcomes: a cohort study and meta-analysis. Cancer Epidemiol Biomarkers Prev. 2012 Sep;21(9):1497-509. doi: 10.1158/1055-9965.EPI-12-0042. Epub 2012 Jun 26. PubMed PMID: 22736790; PubMed Central PMCID: PMC3671609.
  • Flavin R, Pettersson A, Hendrickson WK, Fiorentino M, Finn S, Kunz L, Judson GL, Lis R, Bailey D, Fiore C, Nuttall E, Martin NE, Stack E, Penney KL, Rider JR, Sinnott J, Sweeney C, Sesso HD, Fall K, Giovannucci E, Kantoff P, Stampfer M, Loda M, Mucci LA. SPINK1 protein expression and prostate cancer progression. Clin Cancer Res. 2014 Sep 15;20(18):4904-11. doi: 10.1158/1078-0432.CCR-13-1341. Epub 2014 Mar 31. PubMed PMID: 24687926; PubMed Central PMCID: PMC4167171.
  • Kunz LM, Normand SLT, Marinac-Dabic D, Sedrakyan A, “Meta-analysis of rate ratios with differential follow-up by treatment arm: Inferring comparative effectiveness of medical devices”, Statistics in Medicine. In press.
  • Kunz LM, Rose S, Normand SLT, “An Overview of Approaches to Causal Inference”, Methods in Comparative Effectiveness Research (Gatsonis and Morton editors) and it will be published by CRC Press, Taylor & Francis Group. In press.

Brian J. Sharkey (2008-2013)

Current Position: Principal Biostatistician, Incyte

Publications while in training include:

  • Sharkey B, Lok J, Hughes MD. Estimation of the Cumulative Incidence Function Under Multiple Censoring Mechanisms. Submitted to Biometrics.

Peter J. Lipman (2008-2011)

Current Position: Quantitative Analyst, Google

Publications while in training include:

  • Lipman PJ, Liu KY, Muehlschlegel JD, Body S, Lange C. Inferring genetic causal effects on survival data with associated endo-phenotypes. Genet Epidemiol. 2011 Feb;35(2):119-24. doi: 10.1002/gepi.20557. Epub 2010 Dec 31. PubMed PMID: 21254219; PubMed Central PMCID: PMC3125580.
  • Lipman PJ, Cho MH, Bakke P, Gulsvik A, Kong X, Lomas DA, Anderson W, Silverman EK, Lange C. On the follow-up of genome-wide association studies: an overall test for the most promising SNPs. Genet Epidemiol. 2011 Jul;35(5):303-9. doi: 10.1002/gepi.20578. Epub 2011 Mar 3. PubMed PMID: 21374717; PubMed Central PMCID: PMC4096304.
  • Lipman PJ, Yip WK, AlChawa T, Ludwig KU, Mangold E, Lange C. On the analysis of sequence data: testing for disease susceptibility loci using patterns of linkage disequilibrium. Genet Epidemiol. 2011 Dec;35(8):880-6. doi: 10.1002/gepi.20638. PubMed PMID: 22125225; PubMed Central PMCID: PMC4181609.
  • Lipman PJ, Lange C. CGene: an R package for implementation of causal genetic analyses. Eur J Hum Genet. 2011 Dec;19(12):1292-4. doi: 10.1038/ejhg.2011.122. Epub 2011 Jul 6. PubMed PMID: 21731061; PubMed Central PMCID: PMC3230361.
  • Siedlinski M, Tingley D, Lipman PJ, Cho MH, Litonjua AA, Sparrow D, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Lange C, Silverman EK; COPDGene and ECLIPSE Investigators. Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility. Hum Genet. 2013 Apr;132(4):431-41. doi: 10.1007/s00439-012-1262-3. Epub 2013 Jan 9. PubMed PMID: 23299987; PubMed Central PMCID: PMC3600068.

Norman Huang (2008-2013)

Current Position: Biostatistician, Cerus

Publications while in training include:

  • Huang N, Shah PK, Li C. Lessons from a decade of integrating cancer copy number alterations with gene expression profiles. Brief Bioinform. 2012 May;13(3):305-16. doi: 10.1093/bib/bbr056. Epub 2011 Sep 23. PubMed PMID: 21949216; PubMed Central PMCID: PMC3357489.
  • Yan Z, Shah PK, Amin SB, Samur MK, Huang N, Wang X, Misra V, Ji H, Gabuzda D, Li C. Integrative analysis of gene and miRNA expression profiles with transcription factor-miRNA feed-forward loops identifies regulators in human cancers. Nucleic Acids Res. 2012 Sep 1;40(17):e135. Epub 2012 May 29. PubMed PMID: 22645320; PubMed Central PMCID: PMC3458521.
  • Cinqualbre, J., Kientz, D., Remy, E., Huang, N., Corash, L., & Cazenave, J. P. (2015). Comparative effectiveness of plasma prepared with amotosalen‐UVA pathogen inactivation and conventional plasma for support of liver transplantation. Transfusion. 2015 Apr 9 [epub ahead of print]. PubMed PMID: 25857325. (not NIH funded)
  • Nussbaumer W., Casal, C., Schennach, H., Mayer, W., & Huang, N. Analysis of a 2-Year Experience Before and After Adoption of a Pathogen-Inactivation System for Platelets for Routine Use. Submitted to Transfusion

Chelsea Hertzog (2008- )

Current Position: n/a

Danielle Braun (2008-2014)

Current Position: Research Associate, Biostatistics, Harvard T.H. Chan School of Public Health

Publications while in training include:

  • Karlsson, P., Sun, Z., Braun, D., Price, K. N., Castiglione-Gertsch, M., Rabaglio, M., & Goldhirsch, A. (2011). Long-term results of International Breast Cancer Study Group Trial VIII: adjuvant chemotherapy plus goserelin compared with either therapy alone for premenopausal patients with node-negative breast cancer. Annals of oncology, 22(10), 2216-2226. PMCID: PMC3179412
  • Aebi, S., Sun, Z., Braun, D., Price, K. N., Castiglione-Gertsch, M., Rabaglio, M. & Goldhirsch, A. (2011). Differential efficacy of three cycles of CMF followed by tamoxifen in patients with ER-positive and ER-negative tumors: long-term follow up on IBCSG Trial IX. Annals of oncology, 22(9), 1981-1987. PMCID: PMC3202167.
  • Braun D, Gorfine M, Parmigiani G. Misreported family histories and underestimation of risk. J Clin Oncol. 2014 Nov 10;32(32):3682-3. doi: 10.1200/JCO.2014.57.4848. Epub 2014 Sep 8. PubMed PMID: 25199751 (Comment).
  • Braun, D., Gorfine, M., Zigler, C., Dominici, F., & Parmigiani, G. (2014). Adjustment for Mismeasured Exposure using Validation Data and Propensity Scores. (submitted). Technical report also available Harvard University Biostatistics Working Paper Series. January 2014. Working Paper 172. http://biostats.bepress.com/harvardbiostat/paper172
  • Braun D; Gorfine M; Zigler C; Dominici F; and Parmigiani G. Adjustment for Mismeasured Exposure using Validation Data and Propensity Scores. Harvard University Biostatistics Working Paper Series. January 2014. Working Paper 172. http://biostats.bepress.com/harvardbiostat/paper172
  • Braun, D., Gorfine, M., Katki, H. A., Ziogas, A., & Parmigiani, G. (2014). Nonparametric Adjustment for Measurement Error in Time to Event Data. Technical report also available Harvard University Biostatistics Working Paper Series. January 2014. Working Paper 184. http://biostats.bepress.com/harvardbiostat/paper184
  • Braun, D., Gorfine, M., Katki, H. A., Ziogas, A., Anton-Culver, H., & Parmigiani, G. (2014). Extending Mendelian risk prediction models to handle misreported family history. Technical report available Harvard University Biostatistics Working Paper Series. January 2014. Working Paper 183. http://biostats.bepress.com/harvardbiostat/paper183
  • Chipman, J., Braun, D. (2015). Simpson’s Paradox in the Integrated Discrimination Improvement. (submitted).

Sihai (Dave) Zhao (2007-2012)

Current Position: Assistant Professor, Department of Statistics, University of Illinois at Urbana-Champaign

Publications while in training include:

  • Zhao, S.D. and Li, Y. (2012). Principled sure independence screening for Cox models with ultra-high- dimensional covariates. Journal of Multivariate Analysis 105, 397 – 411. PubMed PMID: 22408278; PubMed Central PMCID: PMC3293491.
  • Nardi, V., Sadow, P.M., Juric, D., Zhao, S.D., et al. (2013). Detection of novel actionable genetic changes in salivary duct carcinoma helps direct patient treatment. Clinical Cancer Research 19, 480 – 490. (not NIH funded)
  • Limaye, S., Riley, S., Zhao, S.D., O’Neill, A., Posner, M., Adkins, D., Jaffa, Z., Clark, J., and Haddad, R. (2013). A randomized phase II study of docetaxel with or without vandetanib in recurrent or metastatic squamous cell carcinoma of head and neck (SCCHN). Oral Oncology 49, 835 – 841. (not NIH funded)
  • Li, Y., Dicker, L., and Zhao, S.D. (2014). The Dantzig selector for censored linear regression
models. Statistica Sinica 24, 251 – 268. PubMed PMID: 24478569; PubMed Central PMCID: PMC3903419.
  • Zhao, S.D., Cai, T.T., and Li, H. (2014). More powerful genetic association testing via a new statistical framework for integrative genomics. Biometrics 70, 881-890. PMCID: PMC4425276
  • Zhao, S.D. and Li, Y. (2014). Score test variable screening. Biometrics 70, 862-871. PubMed PMID: 25124197. PMCID: PMC4427573
  • Zhao, S.D., Parmigiani, G., Huttenhower, C., and Waldron, L. (2014). Más-o-menos: a simple sign averaging method for discrimination in genomic data analysis. Bioinformatics 30, 3062-3069. PubMed PMID: 25061068; PubMed Central PMCID: PMC4201155
  • Hu, X., Feng, Y., Zhang, D., Zhao, S.D., Hu, Z., Greshock, J., Zhang, Y., Yang, L., Zhong, X., Wang, L.-P., Jean, S., Li, C., Huang, Q., Katsaros, D., Montone, K., Tanyi, J.L., Lu, Y., Boyd, J., Nathanson, K.L., Li, H., Mills, G.B., and Zhang, L. (2014). A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in human cancer. Cancer Cell 26, 344-357. PMCID: PMC4159613

Alisa Jane Stephens (2007-2012)

Current Position: Assistant Professor, Biostatistics Unit and Division, University of Pennsylvania

Publications while in training include:

  • Phillips KA, Ribi K, Sun Z, Stephens A, Thompson A, Harvey V, Thurlimann B, Cardoso F, Pagani O, Coates AS, Goldhirsch A, Price KN, Gelber RD and Bernhard J. Cognitive function in postmenopausal women receiving adjuvant letrozole or tamoxifen for breast cancer in the BIG 1-98 randomized trial. Breast. 2010 Oct;19(5):388-95. PMCID: PMC2921449
  • Martin CR, DaSilva DA, Cluette-Brown JE, DiMonda C, Hamill A, Bhutta AQ, Coronel E, Wilschanski M, Stephens AJ, Driscoll DF, Bistrian BR, Ware JH, Zaman MM, Freedman SD (2011). “Decreased Postnatal Docosahexaenoic and Arachidonic Acid Blood Levels in Premature Infants Increase the Risk of Neonatal Morbidities.” Journal of Pediatrics 159, 743-749. PMCID: PMC3701520
  • Stephens AJ, Tchetgen Tchetgen EJ, De Gruttola V. Augmented generalized estimating equations for improving efficiency and validity of estimation in cluster randomized trials by leveraging cluster-level and individual-level covariates. Stat Med. 2012 May 10;31(10):915-30. doi: 10.1002/sim.4471. Epub 2012 Feb 23. PubMed PMID: 22359361; PubMed Central PMCID: PMC3495191.
  • Stephens AJ, Tchetgen Tchetgen EJ, De Gruttola V. Flexible Covariate-adjusted Exact Tests of Randomized Treatment Effects with Application to a Trial of HIV Education. Ann Appl Stat. 2013 Dec 23;7(4):2106-2137. PubMed PMID: 24587845; PubMed Central PMCID: PMC3935423.
  • Garland SN, Carlson LE, Stephens AJ, Antle MC, Samuels C, Campbell TS. Mindfulness-based stress reduction compared with cognitive behavioral therapy for the treatment of insomnia comorbid with cancer: a randomized, partially blinded, noninferiority trial. J Clin Oncol. 2014 Feb 10;32(5):449-57. doi: 10.1200/JCO.2012.47.7265. Epub 2014 Jan 6. PubMed PMID: 24395850. Free full text.
  • Stephens A, Tchetgen Tchetgen E, De Gruttola V. Locally efficient estimation of marginal treatment effects when outcomes are correlated: is the prize worth the chase? Int J Biostat. 2014;10(1):59-75. doi: 10.1515/ijb- 2013-0031. PubMed PMID: 24566369; PubMed Central PMCID: PMC4142698.
  • Krieger JN, Stephens AJ, Landis JR, Clemens JQ, Kreder K, Lai HH, Afari N, Rodríguez L, Schaeffer A, Mackey S, Andriole GL, Williams DA; MAPP Research Network. Relationship between Chronic Nonurological Associated Somatic Syndromes and Symptom Severity in Urological Chronic Pelvic Pain Syndromes: Baseline Evaluation of the MAPP Study. J Urol. 2015 Apr 193)4):1254-62 PMID: 25444992. PMCID in process.
  • Schranz AJ, Brady KA, Momplaisir F, Metlay JP, Stephens A, Yehia BR. Comparison of HIV Outcomes for Patients Linked at Hospital Versus Community-Based Clinics. AIDS Patient Care STDS. 2015 Mar;29(3):117- 25. doi: 10.1089/apc.2014.0199. Epub 2015 Feb 9. PubMed PMID: 25665013; PubMed Central PMCID: PMC4352704.
  • Yehia BR, Ketner E, Momplaisir F, Stephens-Shields AJ, Dowshen N, Eberhart MG, Brady KA. Location of HIV diagnosis impacts linkage to medical care. J Acquir Immune Defic Syndr. 2015 Mar 1;68(3):304-9. doi: 10.1097/QAI.0000000000000459. PubMed PMID: 25469529; PubMed Central PMCID: PMC4326546.
  • Jemmott Iii JB, Jemmott LS, O’Leary A, Icard LD, Rutledge SE, Stevens R, Hsu J, Stephens AJ. On the Efficacy and Mediation of a One-on-One HIV Risk-Reduction Intervention for African American Men Who Have Sex with Men: A Randomized Controlled Trial. AIDS Behav. 2014 Dec 2. [Epub ahead of print] PubMed PMID: 25449552.
  • Jemmott JB 3rd, Stephens-Shields A, O’Leary A, Jemmott LS, Teitelman A, Ngwane Z, Mtose X. Mediation of effects of a theory-based behavioral intervention on self-reported physical activity in South African men. Prev Med. 2015 Mar;72:1-7. doi: 10.1016/j.ypmed.2014.12.022. Epub 2015 Jan 4. PubMed PMID: 25565482; PubMed Central PMCID: PMC4351128.
  • Cunningham GR, Stephens-Shields AJ, Rosen RC, Wang C, Ellenberg SS, Matsumoto AM, Bhasin S, Molitch ME, Farrar JT, Cella D, Barrett-Connor E, Cauley JA, Cifelli D, Crandall JP, Ensrud KE, Fluharty L, Gill TM, Lewis CE, Pahor M, Resnick SM, Storer TW, Swerdloff RS, Anton S, Basaria S, Diem S, Tabatabaie V,
  • Hou X, Snyder PJ. Association of sex hormones with sexual function, vitality, and physical function of symptomatic older men with low testosterone levels at baseline in the testosterone trials. J Clin Endocrinol Metab. 2015 Mar;100(3):1146-55. doi: 10.1210/jc.2014-3818. Epub 2014 Dec 30. PubMed PMID: 25548978; PubMed Central PMCID: PMC4333035.
  • Nickel JC, Stephens A, Landis JR, Chen J, Mullins C, van Bokhoven A, Lucia MS, Melton-Kreft R, Ehrlich GD; The MAPP Research Network. Search for Microorganisms in Men with Urologic Chronic Pelvic Pain Syndrome: A Culture-Independent Analysis in the MAPP Research Network. J Urol. 2015 Jan 14. pii: S0022- 5347(15)00058-0.doi: 10.1016/j.juro.2015.01.037. [Epub ahead of print] PubMed PMID: 25596358.
  • Clemens JQ, Clauw DJ, Kreder K, Krieger J, Kusek JW, Lai H, Rodriguez L, Williams DA, Hou X, Stephens AJ, Landis JR for the MAPP Research Network (2014). “Comparison of Baseline Urologic Symptoms in Men and Women in the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Cohort.” J Urol 2015 Apr; 193(4)1254-62. (PMCID in process).
  • Cauley JA, Fluharty L, Ellenberg S, Gill T, Ensrud K, Barrett-Connor E, Cifelli D, Cunningham GR, Matsumoto AM, Bhasin S, Pahor M, Farrar JT, Cella D, Rosen RC, Resick SM, Swerdloff RS, Lewis CE, Molitch ME, Crandall JP, Stephens AJ, Wang C, Anton S, Basaria S, Diem S, Tabatabaie V, Snyder PJ. Recruitment and Screening for the Testosterone Trials. J Gerontol A Biol Sci Med Sch, 2015 Apr 15 [epub ahead of print] PubMed PMID: 25878029. (PMCID in process)
  • Hsu Y, Kennedy E, Roy J, Stephens-Shields AJ, Small D, Joffe M (2015). “Surrogate Markers for Time- varying Treatments and Outcomes.” Clinical Trials, 2015 May 6 [epub ahead of print] PubMed PMID: 25948621
  • Naliboff BD, Stephens AJ, Afari N, Lai H, Krieger JN, Hong B, Lutgendorf S, Strachan E, Williams D (2015). “Widespread Psychosocial Problems in Male and Female Urologic Chronic Pelvic Pain Syndrome.” Urology, in press.

Anna Catherine Snavely (2007-2012)

Current Position: Co-owner/Consultant Pdstat, Chapel Hill, NC

Publications while in training include:

  • Chapuy CI, Annino DJ, Snavely A, Li Y, Tishler RB, Norris CM, Haddad RI, Goguen LA. Swallowing function following postchemoradiotherapy neck dissection: review of findings and analysis of contributing factors. Otolaryngol Head Neck Surg. 2011 Sep;145(3):428-34. doi: 10.1177/0194599811403075. PubMed PMID: 21493276; PubMed Central PMCID: PMC3434459.
  • Chapuy CI, Annino DJ, Tishler RB, Haddad RI, Snavely A, Goguen LA. Success of endoscopic pharyngoesophageal dilation after head and neck cancer treatment. Laryngoscope. 2013 Dec;123(12):3066- 73. doi: 10.1002/lary.24268. Epub 2013 Jul 8. PubMed PMID: 23775806; PubMed Central PMCID: PMC3844120.
  • Kamande JW, Hupert ML, Witek MA, Wang H, Torphy RJ, Dharmasiri U, Njoroge SK, Jackson JM, Aufforth RD, Snavely A, Yeh JJ, Soper SA. Modular microsystem for the isolation, enumeration, and phenotyping of circulating tumor cells in patients with pancreatic cancer. Anal Chem. 2013 Oct 1;85(19):9092-100. doi: 10.1021/ac401720k. Epub 2013 Sep 10. PubMed PMID: 23947293; PubMed Central PMCID:PMC3832346.
  • Doll KM, Snavely AC, Kalinowski A, Irwin DE, Bensen JT, Bae-Jump V, Boggess JF, Soper JT, Brewster WR, Gehrig PA. Preoperative quality of life and surgical outcomes in gynecologic oncology patients: a new predictor of operative risk? Gynecol Oncol. 2014 Jun;133(3):546-51. doi: 10.1016/j.ygyno.2014.04.002. Epub 2014 Apr 12. PMCID: PMC4058761
  • Boyajian RN, Grose A, Grenon N, Roper K, Sommer K, Walsh M, Snavely A, Neary S, Partridge A, Nekhlyudov L. Desired elements and timing of cancer survivorship care: one approach may not fit all. J Oncol Pract. 2014 Sep;10(5):e293-8. doi: 10.1200/JOP.2013.001192. Epub 2014 Jun 24. PubMed PMID: 24963136. (not federally funded)
  • Snavely AC, Harrington DP, Li Y. A latent variable transformation model approach for exploring dysphagia. Stat Med. 2014 Nov 10;33(25):4337-52. doi: 10.1002/sim.6239. Epub 2014 Jun 29. PubMed PMID: 24974798. (PMCID in process)
  • Smitherman AB, Alexander T, Connelly M, Snavely AC, Weston BW, Liles EA, Steiner MJ. The incidence of catheter-associated venous thrombosis in noncritically ill children. Hosp Pediatr. 2015 Feb;5(2):59-66. doi: 10.1542/hpeds.2014-0041. PubMed PMID: 25646197. (PMCID in process)
  • Doll KM, Kalinowski AK, Snavely AC, Irwin DE, Bensen JT, Bae-Jump VL, Kim KH, Van Le L, Clarke- Pearson DL, Gehrig PA. Obesity is associated with worse quality of life in women with gynecologic malignancies: An opportunity to improve patient-centered outcomes. Cancer. 2015 Feb 1;121(3):395-402. doi: 10.1002/cncr.29061. Epub 2014 Sep 23. PubMed PMID: 25250951; PubMed Central PMCID: PMC4304903.
  • Hertz DL, Snavely AC, McLeod HL, Walko CM, Ibrahim JG, Anderson S, Weck KE, Magrinat G, Olajide O, Moore S, Raab R, Carrizosa DR, Corso S, Schwartz G, Peppercorn JM, Evans JP, Jones DR, Desta Z, Flockhart DA, Carey LA, Irvin WJ Jr. In Vivo Assessment of the Metabolic Activity of CYP2D6 Diplotypes and Alleles. Br J Clin Pharmacol. 2015 Apr 24. doi: 10.1111/bcp.12665. [Epub ahead of print]
  • Sendor AB, Hacker KE, Chen S, Corona AL, Sen O, Chiang DY, Snavely A, Rogers AB, Montgomery SA, Rathmell WK, McRee AJ. Von Hippel-Lindau status influences phenotype of liver cancers arising from PTEN loss. Gastrointest Cancer. 2015 Feb 1;5:61-71. PubMed PMID: 25844041; PubMed Central PMCID: PMC4383253.

Shuli Li (2007-2012)

Current Position: Research Associate, Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute

Publications while in training include:

  • Cutler C, Li S, Ho VT, Koreth J, Alyea E, Soiffer RJ, Antin JH. Extended follow-up of methotrexate-free immunosuppression using sirolimus and tacrolimus in related and unrelated donor peripheral blood stem cell transplantation. Blood. 2007 Apr 1;109(7):3108-14. PubMed PMID: 17138818; PubMed Central PMCID: PMC1852220.
  • Kuzel, T. M.; Li, S.; Eklund, J.; Foss, F.; Gascoyne, R.; Abramson, N.; Schwerkoske, J. F.; Weller, E.; Horning, S. J. “Phase II study of denileukin diftitox for previously treated indolent non-Hodgkin lymphoma: Final results of E1497” Leukemia & Lymphoma 2007, 48(12), 2397- 2402.
  • Dreicer, R.; Li, S.; Manola, J.; Haas, N. B.; Roth, B. J.; Wilding, G. “Phase 2 Trial of Epothilone B Analog BMS-247550 (Ixabepilone) in Advanced Carcinoma of the Urothelium (E3800)” Cancer 2007, 110(4), 759-763.
  • Alyea EP, Li S, Kim HT, Cutler C, Ho V, Soiffer RJ, Antin JH. Sirolimus, tacrolimus, and low-dose methotrexate as graft-versus-host disease prophylaxis in related and unrelated donor reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation. Biol Blood Marrow Transplant. 2008 Aug;14(8):920-6. doi: 10.1016/j.bbmt.2008.05.024. PubMed PMID: 18640576; PubMed Central PMCID: PMC3805273.
  • Volchenboum SL, Li C, Li S, Attiyeh EF, Reynolds CP, Maris JM, Look AT, George RE. Comparison of primary neuroblastoma tumors and derivative early-passage cell lines using genome-wide single nucleotide polymorphism array analysis. Cancer Res. 2009 May 15;69(10):4143-9. doi: 10.1158/0008-5472.CAN-08- 3112. Epub 2009 May 12. PubMed PMID: 19435921; PubMed Central PMCID: PMC2739280.
  • Winter JN, Li S, Aurora V, Variakojis D, Nelson B, Krajewska M, Zhang L, Habermann TM, Fisher RI, Macon WR, Chhanabhai M, Felgar RE, Hsi ED, Medeiros LJ, Weick JK, Weller EA, Melnick A, Reed JC, Horning SJ, Gascoyne RD. Expression of p21 protein predicts clinical outcome in DLBCL patients older than 60 years treated with R-CHOP but not CHOP: a prospective ECOG and Southwest Oncology Group correlative study on E4494. Clin Cancer Res. 2010 Apr 15;16(8):2435-42. doi: 10.1158/1078-0432.CCR-09-1219. Epub 2010 Apr 6. PubMed PMID: 20371683; PubMed Central PMCID: PMC2865202.
  • Argiris, A.; Li, S.; Ghebremichael, M.; Egloff, A. M.; Wang L.; Forastiere, A. A.; Burtness, B.; Mehra, R.; “Prognostic significance of human papillomavirus in recurrent or metastatic head and neck cancer: an analysis of Eastern Coperative Oncology Group trials” Annals of Oncology 2014 Jul;25(7):1410-6. PMCID: PMC4071756
  • Masica DL, Li S, Douville C, Manola J, Ferris RL, Burtness B, Forastiere AA, Koch WM, Chung CH, Karchin R. Predicting survival in head and neck squamous cell carcinoma from TP53 mutation. Hum Genet. 2014 Aug 10. [Epub ahead of print] PubMed PMID: 25108461; PubMed Central PMCID: PMC4324386.
  • Chen YB, Batchelor T, Li S, Hochberg E, Brezina M, Jones S, Del Rio C, Curtis M, Ballen KK, Barnes J, Chi AS, Dietrich J, Driscoll J, Gertsner ER, Hochberg F, LaCasce AS, McAfee SL, Spitzer TR, Nayak L, Armand P. Phase 2 trial of high-dose rituximab with high-dose cytarabine mobilization therapy and high-dose thiotepa, busulfan, and cyclophosphamide autologous stem cell transplantation in patients with central nervous system involvement by non-Hodgkin lymphoma. Cancer. 2015 Jan 15;121(2):226-33. doi: 10.1002/cncr.29023. Epub 2014 Sep 9. PubMed PMID: 25204639; PubMed Central PMCID: PMC4293259.
  • Treister N, Li S, Lerman MA, Lee S, Soiffer R. Narrow-band UVB phototherapy for management of oral chronic graft-versus-host disease. Photodermatol Photoimmunol Photomed. 2015 Mar; 31(2):75-82 PubMed PMID: 25229419 (PMCID in process)
  • Chen YB, Li S, Lane AA, Connolly C, Del Rio C, Valles B, Curtis M, Ballen K, Cutler C, Dey BR, El-Jawahri A, Fathi AT, Ho VT, Joyce A, McAfee S, Rudek M, Rajkhowa T, Verselis S, Antin JH, Spitzer TR, Levis M, Soiffer R. Phase I trial of maintenance sorafenib after allogeneic hematopoietic stem cell transplantation for fms-like tyrosine kinase 3 internal tandem duplication acute myeloid leukemia. Biol Blood Marrow Transplant. 2014 Dec;20(12):2042-8. doi: 10.1016/j.bbmt.2014.09.007. Epub 2014 Sep 17. PubMed PMID: 25239228; PubMed Central PMCID: PMC4253683.
  • Spring L, Li S, Soiffer RJ, Antin JH, Alyea EP 3rd, Glotzbecker B. Risk factors for readmission after allogeneic hematopoietic stem cell transplantation and impact on overall survival. Biol Blood Marrow Transplant. 2015 Mar;21(3):509-16. doi: 10.1016/j.bbmt.2014.11.682. Epub 2014 Dec 5. PubMed PMID: 25482866. (PMCID in process)

Frederick Prichard Cudhea (2007-2013)

Current Position: Research Analyst- Statistician, Department of Nutrition Science and Policy, Tufts University

Layla Mosama Parast Bartroff (2007-2012)

Current Position: Associate Statistician, Rand Corporation

Publications while in training include:

  • Gholami S, Jacobs CD, Kapp DS, Parast LM, Norton JA. The value of surgery for retroperitoneal sarcoma. Sarcoma. 2009;2009:605840. PMCID: PMC2760213.
  • De Jesus M, Parast L, Shelton RC, Kokkinogenis K, Othus MK, Li Y, Allen JD. Actual vs preferred sources of human papillomavirus information among black, white, and Hispanic parents. Arch Pediatr Adolesc Med. 2009 Nov;163(11):1066-7. doi: 10.1001/archpediatrics.2009.211. PMCID: PMC2914618.
  • Cai T, Parast L, Ryan L. Meta-analysis for rare events. Stat Med. 2010 Sep 10;29(20):2078-89. doi: 10.1002/sim.3964. PMCID: PMC2932857.
  • Parast L, Cheng SC, Cai T. Incorporating short-term outcome information to predict long-term survival with discrete markers. Biom J. 2011 Mar;53(2):294-307. doi: 10.1002/bimj.201000150. Epub 2011 Feb 21. PMCID: PMC3472667.
  • Qi L, Parast L, Cai T, Powers C, Gervino EV, Hauser TH, Hu FB, Doria A. Genetic susceptibility to coronary heart disease in type 2 diabetes: 3 independent studies. J Am Coll Cardiol. 2011 Dec 13;58(25):2675-82. doi:10.1016/j.jacc.2011.08.054. PMCID:PMC3240896.
  • Parast L, Cheng SC, Cai T. Landmark Prediction of Long Term Survival Incorporating Short Term Event Time Information. J Am Stat Assoc. 2012;107(500):1492-1501. Epub 2012 Aug 21. PMCID: PMC3535339.
  • Zheng Y, Parast L, Cai T, Brown M. Evaluating incremental values from new predictors with net reclassification improvement in survival analysis. Lifetime Data Anal. 2013 Jul;19(3):350-70. doi: 10.1007/s10985-012-9239-z. Epub 2012 Dec 20. PMCID: PMC3686882.
  • Parast L, Cai T. Landmark risk prediction of residual life for breast cancer survival. Stat Med. 2013 Sep 10;32(20):3459-71. doi: 10.1002/sim.5776. Epub 2013 Mar 14. PMCID: PMC3744612.
  • Parast L, Tian L, Cai T Landmark Estimation of Survival and Treatment Effect in a Randomized Clinical Trial. J Am Stat Assoc. 2014 Jan 1;109(505):384-394. PMCID:PMC3960087
  • Parast L, Doyle B, Damberg CL, Shetty K, Ganz DA, Wenger NS, Shekelle PG.Challenges in Assessing the Process-Outcome Link in Practice. J Gen Intern Med. 2015 Jan 7. [Epub ahead of print] PubMed PMID: 25564435. PMCID: PMC4351283
  • Parast L, Tian L. Robust Estimation of the Proportion of Treatment Effect Explained by Surrogate Marker Information (manuscript in progress)
  • Parast L and Griffin BA, Landmark Estimation of Survival and Treatment Effect in an Observational Study. (manuscript in progress)

Miguel Marino (2006-2011)

Current Position: Assistant Professor, Department of Family Medicine, Oregon Health & Science University

Publications while in training include:

  • Bodonyi-Kovacs G, Putheti P, Marino M, Avihingsanon Y, Uknis ME, Monaco AP, Strom TB, Pavlakis M. Gene expression profiling of the donor kidney at the time of transplantation predicts clinical outcomes 2 years after transplantation. Hum Immunol. 2010 May;71(5):451-5. doi: 10.1016/j.humimm.2010.02.013. Epub 2010 Mar 10. PubMed PMID: 20156509; PubMed Central PMCID: PMC3776421.
  • Williams PL, Marino M, Malee K, Brogly S, Hughes MD, Mofenson LM; PACTG 219C Team. Neurodevelopment and in utero antiretroviral exposure of HIV-exposeduninfected infants. Pediatrics. 2010 Feb;125(2):e250-60. doi: 10.1542/peds.2009-1112. Epub 2010 Jan 18. PubMed PMID: 20083530; PubMed Central PMCID: PMC2951128.
  • Sacks GD, Panchmatia JR, Marino M, Hill C, Rogers SO Jr. The effect of operative timing on functional outcome after isolated spinal trauma. J Trauma. 2011 Dec;71(6):1668-72. doi: 10.1097/TA.0b013e31823246a5. PubMed PMID: 22027884. (not NIH funded)
  • Gillet JP, Calcagno AM, Varma S, Marino M, Green LJ, Vora MI, Patel C, Orina JN, Eliseeva TA, Singal V, Padmanabhan R, Davidson B, Ganapathi R, Sood AK, Rueda BR, Ambudkar SV, Gottesman MM. Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18708-13. doi: 10.1073/pnas.1111840108. Epub 2011 Nov 8. PubMed PMID: 22068913; PubMed Central PMCID: PMC3219108.
  • Jimenez M, Hu FB, Marino M, Li Y, Joshipura KJ. Prospective associations between measures of adiposity and periodontal disease. Obesity (Silver Spring). 2012 Aug;20(8):1718-25. doi: 10.1038/oby.2011.291. Epub 2011 Oct 6. PubMed PMID: 21979390; PubMed Central PMCID: PMC3727227.
  • Jimenez M, Hu FB, Marino M, Li Y, Joshipura KJ. Type 2 diabetes mellitus and 20 year incidence of periodontitis and tooth loss. Diabetes Res Clin Pract. 2012 Dec;98(3):494-500. doi: 10.1016/j.diabres.2012.09.039. Epub 2012 Oct 3. PubMed PMID: 23040240; PubMed Central PMCID: PMC3551264.
  • Harley AE, Sapp AL, Li Y, Marino M, Quintiliani LM, Sorensen G. Sociodemographic and social contextual predictors of multiple health behavior change: data from the Healthy Directions-Small Business study. Transl Behav Med. 2013 Mar;3(1):131-9. doi: 10.1007/s13142-013-0196-1. PubMed PMID: 24073163;
PubMed Central PMCID: PMC3717993.
  • Arlinghaus A, Caban-Martinez AJ, Marino M, Reme SE. The role of ergonomic and psychosocial workplace factors in the reporting of back injuries among U.S. home health aides. Am J Ind Med. 2013 Oct;56(10):1239- 44. doi: 10.1002/ajim.22197. Epub 2013 Jun 26. PubMed PMID: 23804500; PubMed Central PMCID: PMC3809062.
  • Marino M, Li Y, Rueschman MN, Winkelman JW, Ellenbogen JM, Solet JM, Dulin H, Berkman LF, Buxton OM. Measuring sleep: accuracy, sensitivity, and specificity of wrist actigraphy compared to polysomnography. Sleep. 2013 Nov 1;36(11):1747-55. doi: 10.5665/sleep.3142. PubMed PMID: 24179309; PubMed Central PMCID: PMC3792393.
  • Gold R, Bailey SR, OʼMalley JP, Hoopes MJ, Cowburn S, Marino M, Heintzman J, Nelson C, Fortmann SP, DeVoe JE. Estimating demand for care after a Medicaid expansion: lessons from Oregon. J Ambul Care Manage. 2014 Oct-Dec;37(4):282-92. doi: 10.1097/JAC.0000000000000023. PubMed PMID: 24608921; PubMed Central PMCID: PMC4172441.
  • Heintzman J, Bailey SR, Hoopes MJ, Le T, Gold R, O’Malley JP, Cowburn S, Marino M, Krist A, DeVoe JE. Agreement of Medicaid claims and electronic health records for assessing preventive care quality among adults. J Am Med Inform Assoc. 2014 Jul-Aug;21(4):720-4. doi: 10.1136/amiajnl-2013-002333. Epub 2014 Feb 7. PubMed PMID: 24508767; PubMed Central PMCID: PMC4078280.
  • Irvine JM, Hallvik SE, Hildebran C, Marino M, Beran T, Deyo RA. Who uses aprescription drug monitoring program and how? Insights from a statewide survey of Oregon clinicians. J Pain. 2014 Jul;15(7):747-55. doi:
  • 1016/j.jpain.2014.04.003. Epub 2014 Apr 29. PubMed PMID: 24787089; PubMed Central PMCID: PMC4079731.
  • Jacobsen HB, Reme SE, Sembajwe G, Hopcia K, Stiles TC, Sorensen G, Porter JH, Marino M, Buxton OM. Work stress, sleep deficiency, and predicted 10-year cardiometabolic risk in a female patient care worker population. Am J Ind Med. 2014 Aug;57(8):940-9. doi: 10.1002/ajim.22340. Epub 2014 May 8. Erratum in: Am J Ind Med. 2015 Jan;58(1):112. PubMed PMID: 24809311; PubMed Central PMCID: PMC4111954.
  • Bailey SR, O’Malley JP, Gold R, Heintzman J, Marino M, DeVoe JE. Receipt of diabetes preventive services differs by insurance status at visit. Am J Prev Med. 2015 Feb;48(2):229-33. doi: 10.1016/j.amepre.2014.08.035. Epub 2014 Nov 6. PubMed PMID: 25442228; PubMed Central PMCID: PMC4301980.
  • Angier H, Hoopes M, Gold R, Bailey SR, Cottrell EK, Heintzman J, Marino M, DeVoe JE. An early look at rates of uninsured safety net clinic visits after the Affordable Care Act. Ann Fam Med. 2015 Jan-Feb;13(1):10- 6. doi: 10.1370/afm.1741. PubMed PMID: 25583886; PubMed Central PMCID: PMC4291259.
  • Marino M, Li Y, Pencina MJ, D’Agostino RB Sr, Berkman LF, Buxton OM. Quantifying cardiometabolic risk using modifiable non-self-reported risk factors. Am J Prev Med. 2014 Aug;47(2):131-40. doi: 10.1016/j.amepre.2014.03.006. Epub 2014 Jun 17. PubMed PMID: 24951039; PubMed Central PMCID: PMC4107093.
  • 17: Tamers SL, Okechukwu C, Marino M, Guéguen A, Goldberg M, Zins M. Effect of stressful life events on changes in smoking among the French: longitudinal findings from GAZEL. Eur J Public Health. 2015 Mar 11. pii: ckv036. [Epub ahead of print] PubMed PMID: 25762691.
  • 18: Heintzman J, Marino M, Hoopes M, Bailey SR, Gold R, OMalley J, Angier H, Nelson C, Cottrell E, DeVoe J. (2015) Supporting Health Insurance Expansion: Do Electronic Health Records Have Valid Insurance Verification and Enrollment Data? In press: Journal of the American Medical Informatics Association.

Roland Albert Matsouaka (2005-2012)

Current Position: Assistant Professor, Department of Biostatistics and Bioinformatics, Duke University

Publications while in training include:

  • Vaidya VS, Waikar SS, Ferguson MA, Collings FB, Sunderland K, Gioules C, Bradwin G, Matsouaka R, Betensky RA, Curhan GC, Bonventre JV. Urinary biomarkers for sensitive and specific detection of acute kidney injury in humans. Clin Transl Sci. 2008 Dec;1(3):200-8. doi: 10.1111/j.1752-8062.2008.00053.x. PubMed PMID: 19212447; PubMed Central PMCID: PMC2638059.
  • Spires-Jones TL, Kay K, Matsouaka, R, Rozkalne A, Betensky RA, Hyman BT. Calcineurin inhibition with systemic FK506 treatment increases dendritic branching and dendritic spine density in healthy adult mouse brain. Neuroscience Letters. 2011 Jan 10;487(3):260-3. PMCID: PMC3010509
  • Qu J, Matsouaka R, Betensky RA, Hyman BT, Grosskreutz CL. Calcineurin activation causes retinal ganglion cell degeneration. Mol Vis. 2012;18:2828-38. Epub 2012 Nov 29. PubMed PMID: 23233785; PubMed Central PMCID: PMC3519372.
  • Hudry E, Wu HY, Arbel-Ornath M, Hashimoto T, Matsouaka R, Fan Z, Spires-Jones TL, Betensky RA, Bacskai BJ, Hyman BT. Inhibition of the NFAT pathway alleviates amyloid β neurotoxicity in a mouse model of Alzheimer’s disease. J Neurosci. 2012 Feb 29;32(9):3176-92. doi: 10.1523/JNEUROSCI.6439-11.2012. PubMed PMID: 22378890; PubMed Central PMCID: PMC3296329.
  • Matsouaka RA, Li J, Cai T. Evaluating marker-guided treatment selection strategies. Biometrics. 2014 Apr 29. doi: 10.1111/biom.12179. [Epub ahead of print] PubMed PMID: 24779731; PubMed Central PMCID: PMC4213325.
  • Matsouaka RA, Betensky RA. Power and sample size calculations for the Wilcoxon-Mann-Whitney test in the presence of death-censored observations. Stat Med. 2015 Feb 10;34(3):406-31. doi: 10.1002/sim.6355. Epub 2014 Nov 13. PubMed PMID: 25393385; PubMed Central PMCID: PMC4289456.

Rain Cui (2005-2011)

Current Position: Director, Tyco Ventures / Johnson Controls

Publications while in training include:

  • Practice Fusion: A Look at the Possible Effects of Health Records Going Digital. HBS Online Economy Blog, October 2013
  • 
Patient Social Networks: Easy to Start, Harder to Sustain? HBS Digital Innovation and Transformation Blog, March 2014
  • Integrating Genetics with EMR: The Power of Linking “Big Data.” HBS Digital Innovation and Transformation Blog, April 2014

Keith Alexander Betts (2005-2010)

Current Position: Vice President, Analysis Group, Inc

Jing (Jenny) Zhang (2004-2008)

Current Position: Associate Director, Biostatistics, Gilead Sciences

Publications while in training include:

  • Bernhard J, Zahrieh D, Zhang JJ, Martinelli G, Basser R, Hurny C, Forbes JF, Aebi S, Yeo W, Thurlimann 
B, Green MD, Colleoni M, Gelber RD, Castiglione-Gertsch M, Price KN, Goldhirsch A and Coates AS. Quality of life and quality-adjusted survival (Q-TWiST) in patients receiving dose-intensive or standard dose chemotherapy for high-risk primary breast cancer. British Journal of Cancer. 2008 Jan;98(1):25-33. PMCID: PMC2359705).
  • Bernhard J, Zahrieh D, Zhang JJ, Martinelli G, Basser R, Hurny C, Forbes JF, Aebi S, Yeo W, Thurlimann 
B, Green MD, Colleoni M, Gelber RD, Castiglione-Gertsch M, Price KN, Goldhirsch A and Coates AS. Quality of life and quality-adjusted survival (Q-TWiST) in patients receiving dose-intensive or standard dose chemotherapy for high-risk primary breast cancer. British Journal of Cancer. 2008 Jan;98(1):25-33. PMCID: PMC2359705
  • Rothmann M, Koti K, Lee KY, Lu HL, Shen Y, and Zhang JJ (2009). “Examining the extent and impact of missing data in oncology clinical trials.” Joint Statistical Meeting 2009 Proceedings, Biopharmaceutical Section.
  • Zhang JJ and Wang M. Latent class joint model of ovarian function suppression and DFS for premenopausal breast cancer patients. Stat Med. 2010 Sep 30;29(22):2310-24. PMCID: PMC3786368
  • Lemery SJ, Zhang J, Rothmann MD, Yang J, Earp J, Zhao H, McDougal A, Pilaro A, Chiang R, Gootenberg JE, Keegan P, Pazdur R. U.S. Food and Drug Administration approval: ofatumumab for the treatment of patients with chronic lymphocytic leukemia refractory to fludarabine and alemtuzumab. Clin Cancer Res. 2010 Sep 1;16(17):4331-8. doi: 10.1158/1078-0432.CCR-10-0570. Epub 2010 Jul 2. PubMed PMID: 20601446.
  • Zhang J, Zhang JJ. Statistical efficiency in multiple-to-one comparison trials with optimal allocation ratio. J Biopharm Stat. 2011 Jan;21(1):125-35. doi: 10.1080/10543401003642629. PubMed PMID: 21191859. Not funded by NIH.
  • Theoret MR, Ning YM, Zhang JJ, Justice R, Keegan P, Pazdur R. The risks and benefits of 5α-reductase inhibitors for prostate-cancer prevention. N Engl J Med. 2011 Jul 14;365(2):97-9. doi: 10.1056/NEJMp1106783. Epub 2011 Jun 15. PubMed PMID: 21675880. Not funded by NIH.
  • Zhang JJ, Blumenthal GM, He K, Tang S, Cortazar P, Sridhara R. Overestimation of the effect size in group sequential trials. Clin Cancer Res. 2012 Sep 15;18(18):4872-6. doi: 10.1158/1078-0432.CCR-11- 3118. Epub 2012 Jul 2. (FDA supported)
  • Rothmann MD, Zhang JJ, Lu L and Fleming TR. Testing in a Prespecified Subgroup and the Intent-to- Treat Population. Drug Inf J. 2012 Mar 1;46(2):175-9. PMCID: PMC3378054
  • Cruciani RA, Zhang JJ, Manola J, Cella D, Ansari B and Fisch MJ. L-carnitine supplementation for the management of fatigue in patients with cancer: an eastern cooperative oncology group phase III, randomized, double-blind, placebo-controlled trial. J Clin Oncol. 2012 Nov 1;30(31):3864-9. PMCID: PMC3478577
  • Blumenthal GM, Cortazar P, Zhang JJ, Tang S, Sridhara R, Murgo A, Justice R and Pazdur R. FDA approval summary: sunitinib for the treatment of progressive well-differentiated locally advanced or metastatic pancreatic neuroendocrine tumors. Oncologist. 2012;17(8):1108-13. PMCID: PMC3425529
  • Zhang JJ, Chen HY, He K, Tang SH, Justice R, Keegan P, Pazdur R and Sridhara R. Evaluation of Blinded Independent Central Review of Tumor Progression in Oncology Clinical Trials: A Meta-analysis. Ther Innov Regul Sci. [Review]. 2013 Mar;47(2):167-74. (FDA supported)
  • Rothmann M, Koti K, Lee KY, Lu HL, Shen YL, Zhang JJ, Jin M and Zhou H. Evaluating and adjusting for premature censoring of progression-free survival. J Biopharm Stat. 2013;23(5):1091-105. doi: 10.1080/10543406.2013.813526.(FDA supported)
  • Zhang JJ, Zhang L, Chen H, Murgo AJ, Dodd LE, Pazdur R and Sridhara R. Assessment of audit methodologies for bias evaluation of tumor progression in oncology clinical trials. Clin Cancer Res. 2013 May 15;19(10):2637-45. (FDA supported)
  • Zhang J, Zhang JJ. Joint probability of statistical success of multiple phase III trials. Pharm Stat. 2013 Nov-Dec;12(6):358-65. doi: 10.1002/pst.1597. Epub 2013 Sep 16. PubMed PMID: 24106067.(FDA supported)
  • Lin JH, Zhang JJ, Lin SL, Chertow GM. Design of a Phase 2 Clinical Trial of an ASK1 Inhibitor, GS-4997, in Patients with Diabetic Kidney Disease. Nephron Physiol. 2015;129(1):29-33. doi: 10.1159/000369152. Epub 2014 Dec 17. PubMed PMID: 25531162. Not funded by NIH

Michael Chiao-An Wu (2004-2009)

Current Position: Associate Member, Southwest Oncology Group / Public Health Sciences, Fred Hutchinson Cancer Research Center

Publications while in training include:

  • Engbring, J.A., Hossain, R., VanOsdol, S.J., Kaplan-Singer, B., Wu, M, Hibino, S., Koblinski, JE. “The laminin alpha-1 chain derived peptide, AG73, increases fibronectin levels in breast and melanoma cancer cells”. Clinical and Experimental Metastasis, 2008; 25(3):241-52. Epub 2008 Jan 10. (PMID: 18185912)
  • Wu, M, Cai, T, Lin, X. “A parametric permutation test for regression coefficients in LASSO regularized regression.” Submitted to Journal of the American Statistical Association.
  • Wu MC, Zhang L, Wang Z, Christiani DC and Lin X. Sparse linear discriminant analysis for simultaneous testing for the significance of a gene set/pathway and gene selection. Bioinformatics, 2009; 25(9): 1145-51.
  • Huang YT, Heist RS, Chirieac LR, Lin X, Skaug V, Zienolddiny S, Haugen A, Wu MC, Wang Z, Su L, Asomaning K and Christiani DC. Genome-Wide Analysis of Survival in Early-Stage Non-Small-Cell Lung Cancer. J Clin Oncol, 2009.
  • Harezlak J, Wu MC, Wang M, Schwartzman A, Christiani DC and Lin X. Biomarker discovery for arsenic exposure using functional data. Analysis and feature learning of mass spectrometry proteomic data. J Proteome Res, 2008; 7(1): 217-24.
  • Ji H, Ramsey MR, Hayes DN, Fan C, McNamara K, Kozlowski P, Torrice C, Wu MC, Shimamura T, Perera SA, Liang MC, Cai D, Naumov GN, Bao L, Contreras CM, Li D, Chen L, Krishnamurthy J, Koivunen J, Chirieac LR, Padera RF, Bronson RT, Lindeman NI, Christiani DC, Lin X, Shapiro GI, Janne PA, Johnson BE, Meyerson M, Kwiatkowski DJ, Castrillon DH, Bardeesy N, Sharpless NE and Wong KK. LKB1 modulates lung cancer differentiation and metastasis. Nature, 2007; 448(7155): 807-10.

Megan Kay Diane Othus (2004-2009)

Current Position: Assistant Member, Fred Hutchinson Cancer Research Center

Publications while in training include:

Patrick M. Loerch (2003-2009)

Current Position: Assistant Member, Fred Hutchinson Cancer Research Center

Publications while in training include:

  • Armour CD, Castle JC, Chen R, Babak T, Loerch P, Jackson S, Shah JK, Dey J, Rohl CA, Johnson JM, Raymond CK. (2009) Digital transcriptome profiling using selective hexamer priming for cDNA synthesis. Nat Methods; 6(9):647-9. Epub 2009 Aug 9. PMCID: PMC Journal – In Process.
  • Yankner BA, Lu T and Loerch P. (2008) The aging brain. Annu Rev Pathol; 3: 41-66.
  • Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW and Sinclair DA. (2008) SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell; 135(5): 907-18. PMCID: PMC2853975.
  • Loerch PM, Lu T, Dakin KA, Vann JM, Isaacs A, Geula C, Wang J, Pan Y, Gabuzda DH, Li C, Prolla TA and Yankner BA. (2008) Evolution of the aging brain transcriptome and synaptic regulation. PLoS ONE, 3(10): e3329. PMCID: PMC2553198.
  • Castle, J; Garrett-Engele, P; Armour, CD; Duenwald, SJ; Loerch, PM; Meyer, MR; Schadt, EE; Stoughton, R; Parrish, ML; Shoemaker, DD; Johnson, JM. (2003) Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing. Genome Biology; 4 (10): art. no.-R66. PMCID: PMC328455
  • Johnson, JM; Castle, J; Garrett-Engele, P; Kan, ZY; Loerch, PM; Armour, CD; Santos, R; Schadt, EE; Stoughton, R; Shoemaker, DD. Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. (2003) Science, 2003; 302 (5653): 2141-2144.

William E. Johnson, Jr. (2003-2007)

Current Position: Associate Professor of Medicine, Division of Computational Biomedicine, Boston University School of Medicine

Publications while in training include:

  • Johnson WE, Li W, Meyer CA, Gottardo R, Carroll JS, Brown M, Liu XS. (2006) Model-based analysis of tiling-arrays for ChIP-chip. Proc Natl Acad Sci U S A; 103(33):12457-62. Epub 2006 Aug 8. PMCID: PMC1567901.
  • Johnson WE, Li C, Rabinovic A. Adjusting batch e_ects in microarray expression data using em- pirical Bayes methods. Biostatistics. 2007 Jan;8(1):118-27. PubMed PMID: 16632515.
  • Song JS, Johnson WE, Zhu X, Zhang X, Li W, Manrai AK, Liu JS, Chen R, Liu XS. (2007) Model-based analysis of two-color arrays (MA2C). Genome Biol; 8(8):R178. PMCID: PMC2375008.
  • Gottardo R, Li W, Johnson WE, Liu XS. (2008) A flexible and powerful Bayesian hierarchical model for ChIP-Chip experiments. Biometrics; 64(2):468-78. Epub 2007 Sep 20. PMID: 17888037
  • Hollenhorst PC, Chandler KJ, Poulsen RL, Johnson WE, Speck NA, Graves BJ. (2009) DNA specificity determinants associate with distinct transcription factor functions. PLoS Genet, 5(12):e1000778. Epub 2009 Dec 18. PMCID: PMC2787013.
  • Thyagarajan B, Blaszczak AG, Chandler KJ, Watts JL, Johnson WE, Graves BJ (2010) ETS-4 Is a Transcriptional Regulator of Life Span in Caenorhabditis elegans. PLoS Genetics 6 (9): e1001125. PMCID: PMC2940738
  • Rai K, Sarkar S, Broadbent T, Voas M, Grossman KF, Dehghanizadeh S, Hagos F, ∗Li Y, Toth RK, Chidester S, †Bahr TM, Johnson WE, Sklow B, Burt R, Cairns BR, Jones DA (2010). DNA Demethylase Activity Maintains Zebrafish Intestinal Cells in a Progenitor-like State Following Loss of APC. Cell 142 (6): 930-942. PMCID: PMC2943938
  • Leek JT, Scharpf R, Corrada-Bravo H, Simcha D, Langmead B, Johnson WE, Geman D, Baggerly K, Irizarry RA (2010). Tackling the widespread and critical impact of batch effects in high-throughput data. Nature Reviews Genetics 11, 733–739. PMCID: PMC3880143
  • Johnson WE, Welker NC, Bass BL (2011). Dynamic Linear Model for the Identification of miRNAs in Next-generation Sequencing Data. Biometrics 67: 1206-14. PMCID: PMC3116054
  • Warf MB, Johnson WE, Bass BL (2011). Improved annotation of C. elegans microRNAs by deep sequencing reveals structures associated with processing by Drosha and Dicer. RNA 17: 563-577. PMCID: PMC3062169
  • Lyon GJ, Jiang T, Van Wijk R, Wang W, Bodily PM, Xing J, Tian L, Robison RJ, Clement M,
Lin Y, Zhang P, Liu Y, Moore B, Glessner JT, Elia J, Reimherr F, van Solinge WW, Yandell M, Hakonarson H, Wang J, Johnson WE, Wei Z, Wang K. Exome sequencing and unrelated findings in the context of complex disease research: ethical and clinical implications. Discovery Medicine. 2011 Jul;12(62):41-55. PubMed PMID: 21794208; PubMed Central PMCID: PMC3544941.
  • Rope AF, Wang K, Evjenth R, Xing K, Johnston JJ, Swenson JJ, Johnson WE, Moore B, Huff
CD, Bird LM, Carey JC, Opitz JM Stevens CA, Jiang T, Schank C, Fain HD, Robison R, Dalley
B, Chin S, South TS, Pysher TJ, Jorde LB, Hakonarson H, Lillehaug JR, Biesecker LG, Yandell M,
Arnesen T, Lyon GJ (2011). Using VAAST to Identify an X-Linked Disorder Resulting in Lethality in Male Infants Due to N-Terminal Acetyltransferase Deficiency. Am J Hum Genet. 2011 Jul 15;89(1):28-43. PMCID: PMC3135802
  • Cohen AL, Soldi R, Zhang H, Gustafson AM, Wilcox R, Welm BE, Chang JT, Johnson WE, Spira A, Jeffrey SS, Bild AH (2011). MATCH: Merging genomic and pharmacologic Analyses for Therapy CHoice. Mol Syst Biol. 2011 Jul 19;7:513. PMCID: PMC3159972
  • Leek JT, Johnson WE, Parker HS, Ja_e AE, Storey JD. The sva package for removing batch effects and other unwanted variation in high-throughput experiments. Bioinformatics. 2012 Mar 15;28(6):882-3. PubMed PMID: 22257669; PubMed Central PMCID: PMC3307112.
  • Warf MB, Shepherd BA, Johnson WE, Bass BL. E_ects of ADARs on small RNA processing path- ways in C elegans. Genome Research. 2012 Aug;22(8):1488-98. PubMed PMID: 22673872; PubMed Central PMCID: PMC3409262.
  • Piccolo SR, Sun Y, Campbell JD, Lenburg ME, Bild AH, Johnson WE. A single-sample microarray normalization method to facilitate personalized-medicine workows. Genomics. 2012 Dec;100(6):337- 44. PubMed PMID: 22959562; PubMed Central PMCID: PMC3508193.
  • O’Rawe J, Jiang T, Sun G,Wu Y,Wang W, Hu J, Bodily P, Tian L, Hakonarson H, Johnson WE,Wei
Z, Wang K, Lyon GJ. Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing. Genome Medicine. 2013;5(3):28. PubMed PMID: 23537139; PubMed Central PMCID: PMC3706896.
  • Woolstenhulme CJ, Parajuli S, Healey DW, Valverde DP, Petersen EN, Starosta AL, Guydosh NR, Johnson WE, Wilson DN, Buskirk AR. Nascent peptides that block protein synthesis in bacteria. Proceedings of the National Academy of Sciences. 2013 Mar 5;110(10):E878-87. PubMed PMID: 23431150; PubMed Central PMCID: PMC3593848.
  • Cohen AL, Piccolo SR, Cheng L, Soldi R, Han B, Johnson WE, Bild AH. Genomic pathway analysis reveals that EZH2 and HDAC4 represent mutually exclusive epigenetic pathways across human cancers. BMC Medical Genomics. 2013 Sep 30;6:35. PubMed PMID: 24079712; PubMed Central PMCID: PMC3850967.
  • Francis OE, Bendall M, Manimaran S, Hong C, Clement NL, Castro-Nallar E, Snell Q, Schaalje GB, Clement MJ, Crandall KA, Johnson WE. Pathoscope: species identi_cation and strain attribution with unassembled sequencing data. Genome Research. 2013 Oct;23(10):1721-9. PubMed PMID: 23843222; PubMed Central PMCID: PMC3787268.
  • Piccolo SR, Withers MR, Francis OE, Bild AH, Johnson WE. Multiplatform single-sample estimates of transcriptional activation. Proceedings of the National Academy of Sciences. 2013 Oct 29;110(44):17778-83. PubMed PMID: 24128763; PubMed Central PMCID: PMC3816418.
  • Hong C, Clement NL, Clement S, Hammoud SS, Carrell DT, Cairns BR, Snell Q, Clement MJ, Johnson WE. Probabilistic alignment leads to improved accuracy and read coverage for bisul_te sequencing data. BMC Bioinformatics. 2013 Nov 21;14:337. PubMed PMID: 24261665; PubMed Central PMCID: PMC3924334.
  • Bild AH, Chang JT, Johnson WE, Piccolo SR. A field guide to genomics research. PLOS Biology. 2014 Jan;12(1):e1001744. PubMed PMID: 24409093; PubMed Central PMCID: PMC3883637.
  • Hong C, Manimaran S, Shen Y, Perez-Rogers JF, Byrd AL, Castro-Nallar E, Crandall KA, Johnson WE. PathoScope 2.0: a complete computational framework for strain identi_cation in environmental or clinical sequencing samples. Microbiome. 2014; 2:33. PubMed PMID: 25225611; PubMed Central PMCID: PMC4164323.
  • Byrd AL, Perez-Rogers JF, Manimaran S, Castro-Nallar E, Toma I, McCa_rey T, Siegel M, Benson G, Crandall KA, Johnson WE. Clinical PathoScope: rapid alignment and _ltration for accurate pathogen identi_cation in clinical samples using unassembled sequencing data. BMC Bioinformatics. 2014 Aug 4;15:262. PubMed PMID: 25091138; PubMed Central PMCID: PMC4131054.
  • Shamsaddini A, Pan Y, Johnson WE, Krampis K, Shcheglovitova M, Simonyan V, Zanne A, Mazumder R. Census-based rapid and accurate metagenome taxonomic pro_ling. BMC Genomics. 2014 Oct 21;15:918. PubMed PMID: 25336203; PubMed Central PMCID: PMC4218995.
  • Hong C, Manimaran S, Johnson WE. PathoQC: Computationally e_cient read pre-processing and quality control for high throughput sequencing datasets. Cancer Informatics (in press).

Derek S. Elmerick (2003-2005)

Current Position: Vice President, First Manhattan Consulting Group

James E. Signorovitch (2002-2007)

Current Position: Vice President, Analysis Group

Publications while in training include:

  • “Hospital visits and costs following outpatient treatment of CAP with levofloxacin or moxifloxacin” Signorovitch JE, Sheng Duh M, Sengupta A, Gu A, Grant R, Raut M, Mody SH, Schein J, Fisher AC, Ng D. Curr Med Res Opin. 2010 Feb;26(2):355-63. (PMID: 19995325)
  • Moukarbel GV, Signorovitch JE, Pfeffer MA, McMurray JJ, White HD, Maggioni AP, Velazquez EJ, Califf RM, Scheiman JM, Solomon SD. “Gastrointestinal bleeding in high risk survivors of myocardial infarction: the VALIANT Trial” Eur Heart J. 2009 Sep;30(18):2226-32. Epub 2009 Jun 25. (PMID: 19556260)
  • Sadow CA, Silverman SG, O’Leary MP, Signorovitch JE. “Bladder cancer detection with CT urography in an Academic Medical Center” Radiology. 2008 Oct;249(1):195-202. (PMID: 18796677)
  • “Effect of antecedent hypertension and follow-up blood pressure on outcomes after high-risk myocardial infarction” Thune JJ, Signorovitch J, Kober L, Velazquez EJ, McMurray JJ, Califf RM, Maggioni AP, Rouleau JL, Howlett J, Zelenkofske S, Pfeffer MA, Solomon SD. Hypertension. 2008 Jan;51(1):48-54. Epub 2007 Nov 19. (PMID: 18025296)
  • Storch KF, Paz C, Signorovitch J, Raviola E, Pawlyk B, Li T, Weitz CJ. “Intrinsic circadian clock of the mammalian retina: importance for retinal processing of visual information” Cell. 2007 Aug 24;130(4):730-41. (PMID: 17719549)
  • Karlson EW, Watts J, Signorovitch J, Bonetti M, Wright E, Cooper GS, McAlindon TE, Costenbader KH, Massarotti EM, Fitzgerald LM, Jajoo R, Husni ME, Fossel AH, Pankey H, Ding WZ, Knorr R, Condon S, Fraser PA. “Effect of glutathione S-transferase polymorphisms and proximity to hazardous waste sites on time to systemic lupus erythematosus diagnosis: results from the Roxbury lupus project.”Arthritis Rheum. 2007 Jan;56(1):244-54. (PMID: 17195228)
  • Clark AG, Nielsen R, Signorovitch J, Matise TC, Glanowski S, Heil J, Winn-Deen ES, Holden AL, Lai E. “Linkage disequilibrium and inference of ancestral recombination in 538 single-nucleotide polymorphism clusters across the human genome” Am J Hum Genet. 2003 Aug;73(2):285-300. Epub 2003 Jul 3. (PMID: 12844287)
  • Nielsen R, Signorovitch J. “Correcting for ascertainment biases when analyzing SNP data: applications to the estimation of linkage disequilibrium” Theor Popul Biol. 2003 May;63(3):245-55. (PMID: 12689795)

William N. King (2002-2003)

Current Position: President/Founder Western Statistical Consulting, LLC

Jeffrey D. Bears (2002-2004)

Current Position: Intellectual Property Manager & Legal Counsel, LifeQ

Elizabeth A. Whalen (2001-2006)

Current Position: Bioinformatician II, Benaroya Research Institute at Virginia Mason (BRI)

Publications while in training include:

  • Carey VJ, Gentry J, Whalen E, Gentleman R. “Network structures and algorithms in Bioconductor” Bioinformatics. 2005 Jan 1;21(1):135-6. Epub 2004 Aug 5. (PMID: 15297301)

Jennifer Schumi (1999-2004)

Current Position: Senior Principal Biostatistician, Boehringer Ingelheim Pharmaceuticals, Inc.

Publications while in training include:

  • Tardif JC, McMurray JJ, Klug E, Small R, Schumi J, Choi J, Cooper J, Scott R, Lewis EF, L’Allier PL, Pfeffer MA; Aggressive Reduction of Inflammation Stops Events (ARISE) Trial Investigators. “Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, double-blind, placebo-controlled trial” Lancet. 2008 May 24;371(9626):1761-8. (PMID: 18502300)
  • Schumi J, Degruttola V. “Resampling-based analyses of the effects of combinations of HIV genetic mutations on drug susceptibility” Stat Med. 2008 Oct 15;27(23):4740-57.PMID: 18186529
  • Schumi J, Dirienzo AG, Degruttola V. “Testing for Associations with Missing High-Dimensional Categorical Covariates” Int J Biostat. 2008 Sep 29;4(1):Article18. (PMID: 20231909)
  • Mello MM, Studdert DM, Schumi J, Brennan TA, Sage WM. “Changes in physician supply and scope of practice during a malpractice crisis: evidence from Pennsylvania” Health Aff (Millwood). 2007 May- Jun;26(3):w425-35. Epub 2007 Apr 24. (PMID: 17456502)

Kevin A. Rader (2001-2014)

Current Position: Senior Preceptor, Department of Statistics, Harvard University

Publications while in training include:

  • Cripe LD, Rader K, Tallman MS, Gordon MS, Paietta E, Bennett J, Neuberg D, Litzow MR, O’brien TE, Rowe JM. “Phase II trial of subcutaneous recombinant human interleukin 11 with subcutaneous recombinant human granulocyte-macrophage colony stimulating factor in patients with acute myeloid leukemia (AML) receiving high-dose cytarabine during induction: ECOG 3997.”Leuk Res. 2006 Jul;30(7):823-7. Epub 2006 Jan 18.(PMID: 16413056)

Heather J. Litman (2001-2005)

Current Position: Senior Biostatistician, The Consortium of Rheumatology Researchers of North America, Inc. (CORRONA)

Publications while in training include:

  • Litman HJ, Horton NJ, Murphy JM, Laird NM. (2006) Marginal regression models with a time to event outcome and discrete multiple source predictors. Lifetime Data Anal; 12(3):249-65. Epub 2006 Aug 2. PMCID: PMC1851698
  • Litman HJ, Bhasin S, Link CL, Araujo AB, McKinlay JB. (2006) Serum androgen levels in black, Hispanic, and white men. J Clin Endocrinol Metab; 91(11):4326-34. Epub 2006 Aug 15.
  • Viswanathan AN, Grier HE, Litman HJ, et al. (2004) Outcome for Children with Group III Rhabdomyosarcoma treated with or without radiotherapy. Int. J. Radiation Oncology Biol. Phys.; 58: 1208-1214.
  • Spataro V, Litman H, Viale G, et al. (2003) Decreased Immunoreactivity for p27 Protein in Patients with Early- Stage Breast Carcinoma Is Correlated with HER-2/neu Overexpression and with Benefit from One Course of Perioperative Chemotherapy in Patients with Negative Lymph Node Status. Cancer; 97: 1591-1600.
  • Marcus KJ, Shamberger R, Litman H, von Allmen D, Grupp SA, Nancarrow CM, Goldwein J, Grier HE, Diller L. (2003) Primary tumor control in patients with stage 3/4 unfavorable neuroblastoma treated with tandem double autologous stem cell transplants. J Pediatr Hematol Oncol; 25(12):934-40.
  • Spataro VJ, Litman H, Viale G, Maffini F, Masullo M, Golouh R, Martinez-Tello FJ, Grigolato P, Shilkin KB, Gusterson BA, Castiglione-Gertsch M, Price K, Lindtner J, Cortés-Funes H, Simoncini E, Byrne MJ, Collins J, Gelber RD, Coates AS, Goldhirsch A; International Breast Cancer Study Group. (2003) Decreased immunoreactivity for p27 protein in patients with early-stage breast carcinoma is correlated with HER-2/neu overexpression and with benefit from one course of perioperative chemotherapy in patients with negative lymph node status: results from International Breast Cancer Study Group Trial V. Cancer; 97(7):1591-600.
  • Colleoni M, Litman HJ, Castiglione-Gertsch M, et al. (2002) Duration of adjuvant chemotherapy for breast cancer: a joint analysis of two randomized trials investigating three versus six courses of CMF. British Journal Of Cancer; 86: 1705-1714.
  • Diller L, Medeiros Nancarrow C, Shaffer K, Matulonis U, Mauch P, Neuberg D, Tarbell NJ, Litman H, Garber J. (2002) Breast cancer screening in women previously treated for Hodgkin’s disease: a prospective cohort study. J Clin Oncol; 20(8):2085-91.

Ping Gray (2001-2005)

Current Position: Research Scientist Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute

Suzanne Dahlberg (2001-2005)

Current Position: Senior Research Scientist, Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute

Publications while in training include:

  • Gutierrez A, Sanda T, Ma W, Zhang J, Grebliunaite R, Dahlberg S, Neuberg D, Protopopov A, Winter SS, Larson RS, Borowitz MJ, Silverman LB, Chin L, Hunger SP, Jamieson C, Sallan SE, Look AT. “Inactivation of LEF1 in T-cell acute lymphoblastic leukemia.” Blood. 2010 Feb 1. (PMID: 20124220)
  • Dahlberg SE, Sandler AB, Brahmer JR, Schiller JH, Johnson DH. “Clinical course of advanced non-small-cell lung cancer patients experiencing hypertension during treatment with bevacizumab in combination with carboplatin and paclitaxel on ECOG 4599.” J Clin Oncol. 2010 Feb 20;28(6):949-54. Epub 2010 Jan 19.(PMID: 20085937)
  • Giles KA, Hamdan AD, Pomposelli FB, Wyers MC, Dahlberg SE, Schermerhorn ML. “Population-based outcomes following endovascular and open repair of ruptured abdominal aortic aneurysms.” J Endovasc Ther. 2009 Oct;16(5):554-64.(PMID: 19842719)
  • Horn L, Dahlberg SE, Sandler AB, Dowlati A, Moore DF, Murren JR, Schiller JH. “Phase II study of cisplatin plus etoposide and bevacizumab for previously untreated, extensive-stage small-cell lung cancer: Eastern Cooperative Oncology Group Study E3501.” J Clin Oncol. 2009 Dec 10;27(35):6006-11. Epub 2009 Oct 13. (PMID: 19826110)
  • Gutierrez A, Sanda T, Grebliunaite R, Carracedo A, Salmena L, Ahn Y, Dahlberg S, Neuberg D, Moreau LA, Winter SS, Larson R, Zhang J, Protopopov A, Chin L, Pandolfi PP, Silverman LB, Hunger SP, Sallan SE, Look AT. “High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia.” Blood. 2009 Jul 16;114(3):647-50. Epub 2009 May 20.PMID: 19458356
  • Kearney SL, Dahlberg SE, Levy DE, Voss SD, Sallan SE, Silverman LB. “Clinical course and outcome in children with acute lymphoblastic leukemia and asparaginase-associated pancreatitis.” Pediatr Blood Cancer. 2009 Aug;53(2):162-7.(PMID: 19405141)
  • Simosa HF, Pomposelli FB, Dahlberg S, Scali ST, Hamdan AD, Schermerhorn ML. “Predictors of failure after angioplasty of infrainguinal vein bypass grafts.” J Vasc Surg. 2009 Jan;49(1):117-21. Epub 2008 Nov 22. (PMID: 19028063)
  • Barry EV, Vrooman LM, Dahlberg SE, Neuberg DS, Asselin BL, Athale UH, Clavell LA, Larsen EC, Moghrabi A, Samson Y, Schorin MA, Cohen HJ, Lipshultz SE, Sallan SE, Silverman LB. “Absence of secondary malignant neoplasms in children with high-risk acute lymphoblastic leukemia treated with dexrazoxane.” J Clin Oncol. 2008 Mar 1;26(7):1106-11. (PMID: 18309945)
  • Dahlberg SE, Wang M. “A proportional hazards cure model for the analysis of time to event with frequently unidentifiable causes.” Biometrics. 2007 Dec;63(4):1237-44. (PMID: 18078485)
  • Pandya KJ, Dahlberg S, Hidalgo M, Cohen RB, Lee MW, Schiller JH, Johnson DH; Eastern Cooperative Oncology Group (E1500).“A randomized, phase II trial of two dose levels of temsirolimus (CCI-779) in patients with extensive-stage small-cell lung cancer who have responding or stable disease after induction chemotherapy: a trial of the Eastern Cooperative Oncology Group (E1500).” J Thorac Oncol. 2007 Nov;2(11):1036-41.(PMID: 17975496)
  • Patel VI, Hamdan AD, Schermerhorn ML, Hile C, Dahlberg S, Campbell DR, LoGerfo FW, Pomposelli FB. “Lower extremity arterial revascularization in obese patients.”J Vasc Surg. 2007 Oct;46(4):738-42. Epub 2007 Aug 30. (PMID: 17764878)
  • Zhou J, Goldwasser MA, Li A, Dahlberg SE, Neuberg D, Wang H, Dalton V, McBride KD, Sallan SE, Silverman LB, Gribben JG; Dana-Farber Cancer Institute ALL Consortium. “Quantitative analysis of minimal residual disease predicts relapse in children with B-lineage acute lymphoblastic leukemia in DFCI ALL Consortium Protocol 95-01.” Blood. 2007 Sep 1;110(5):1607-11. Epub 2007 May 7. (PMID: 17485550)
  • Szwarc, SE, Bonetti M. Modelling menstrual status during and after adjuvant treatment for breast cancer. Stat Med. 2006 Oct 30;25(20):3534-47. (PMID: 16345025)

Lu (Summer) Zheng (2000-2005)

Current Position: Research Scientist Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health

Publications while in training include:

  • Smith K, Zheng L, Bosch R, Margolis D, Tenorio A, Napolitano L, Saag M, Connick E, Gross B, Frances I, Valdez H, Muurahainen N, Stocker V, and Pollard R. (2010) Treatment with Recombinant Growth Hormone is Associated with Modest Improvement in CD4 Lymphocyte Reconstitution in HIV-Infected Persons on Antiretroviral Therapy: Results of ACTG A5174. AIDS research and human retroviruses; 26(4): 425-432. PMCID: PMC2864047.
  • Twigg HL, Schnizlein-Bick C, Weiden M, Valentine F, Wheat J, Day R, Rominger H, Zheng L, Collman R, Coombs R, Pat Bucy R, Rezk N, and Kashuba A. (2010)( Measurement of Antiretroviral Drugs into the Lungs of HIV-infected Patients. HIV Therapy; 4(2): 247-251. PMCID: PMC2861507.
  • Zheng L, Zelen M. (2009) Urn sampling, interval censoring and proportional hazard models: tests and relationships. Statistical Modeling; 9(4): 361-379.
  • Zheng L, Zelen M. (2008) Multi-center clinical trials: randomization and ancillary statistics. Annals of Applied Statistics; 2(2): 582-600.
  • Twigg HL, Weiden M, Valentine F, Schnizlein-Bick C, Bassett R, Zheng L, Wheat J, Day R, Rominger H, Collman R, Fox L, Brizz B, Dragavon J, Coombs R, and Pat Bucy R. (2008) Effect of highly active antiretroviral therapy on viral burden in the lungs of HIV-infected subject. Journal of Infectious Diseases; 197:109-116.
  • Zheng, L; Zelen, M. (2003) Tests and relationships among urn sampling, interval censoring and proportional hazard models. Controlled Clinical Trials; 24: 240S-240S, Suppl. 3.

Yannis Jemiai (2000-2005)

Current Position: Senior Vice President Strategic Consulting, Software Solutions & Marketing, Cytel Software Corporation

Yihua Zhao (1999-2004)

Current Position: Senior Principal Biostatistician, Boehringer Ingelheim Pharmaceuticals, Inc.

Bin Zhang (1999-2005)

Current Position: Global Director, Seqirus

Michael Jon Szarek (1999-2002)

Current Position: Associate Dean for Research Admin, Professor and Chair Dept of Epidemiology and Biostatistics, SUNY Downstate Medical Center

Marie Denise Scholtens (1999-2004)

Current Position: Associate Professor Preventive Medicine, Northwestern Medical School

David Loecke (1999-2005)

Current Position: Legal and Biostatistical Consultant in Biotechnology/Pharmaceutical industry

Carlos D. Brain (1999-2001)

Current Position: Principal, Cornerstone Research

Amy L. Pace (1998-2003)

Current Position: Director of Biostatistics, Alexion Pharmaceuticals, Inc

Abigail G. Matthews (1998-2005)

Current Position: Biostatistician, Emmes Corporation

Jie Huang (1998-2002)

Current Position: Senior Director and Head of Biometrics, Forty Seven, Inc.

Jared Christensen (1998-2004)

Current Position: Director, Pfizer, Inc.

Postdoctoral Alumni

 

Patricia Stephenson
Academic advisor: Marvin Zelen
Research topic: Noncompliance in Randomized Clinical Trials and the Potential Benefit of Early Detection of Ovarian Cancer
Current position: Principal Statistical Scientist I, Rho, Inc.

Matthew Finkelman
Academic advisor: David Harrington and Alan Zaslavsky
Research topic: Methods research in the area of population based observations studies
Current position: Associate Professor, Department of Biostatistics, Tufts University School of Dental Medicine

Ann Lazar
Academic advisor: Richard Gelber and Rober Gray
Research topic: Longitudinal methods, methods for subgroup analysis, analysis of high-dimensional genomic (or other biomarker) data, design of clinical biomarker studies, or other clinical trial design issues
Current position: Assistant Professor, University of California at San Francisco School of Dentistry, Preventive & Restorative Dental Sciences

Cristian Tomasetti
Academic advisor: Giovanni Parmigiani
Research topic: Methodological and collaborative cancer research
Current position: Assistant Professor, Division of Biostatistics and Bioinformatics /Department of Oncology, Johns Hopkins University

Michael I. Love
Academic advisor: Rafael Irizarry
Research topic: Developing statistical and computational methods for data produced by high throughput technologies
Current position: Assistant Professor, Department of Biostatistics, University of North Carolina-Chapel Hill