Nurses’ Health Study (NHS I) and Nurses’ Health Study II (NHS II)

Site: https://nurseshealthstudy.org

Updated 5/16/22

Country: United States

Study design: Observational cohort with repeated measurements over time

Participant age range: Early adulthood or midlife at enrollment

Number of participants at baseline: 121,700 (NHS I); 116,430 (NHS II)

Year of initial enrollment: 1976 (NHS I); 1989 (NHS II)

Number of data collection waves: 23 (NHS I) and 17 (NHS II); data collection ongoing

Measures of well-being:

  • Optimism
  • Purpose / Meaning in Life / Ikigai
  • Life Satisfaction

Quantity of well-being measures (e.g., number of constructs, number of times well-being was assessed): Moderate

Quality of well-being measures (e.g., were measures reliable and valid in the study population): High

Measures of physical health: 

  • Self-rated / questionnaire-based health
  • Self-report medical history or medication use
  • Measured anthropometrics, e.g., weight
  • Biomarkers
  • Genetics
  • Linked medical records
  • Adjudicated health outcomes

Access Information:

This dataset is available to all researchers.

Researchers are required to apply to access this data.

Fees are required to access this dataset.

Notable citation:

Kim E, Hagan K, Grodstein F, DeMeo D, De Vivo I, & Kubzansky L. (2017). Optimism and cause-specific mortality: a prospective cohort study. American journal of epidemiology, 185(1), 21-29.