Women’s Health Initiative (WHI)

Site: www.whi.org/datasets

Updated 5/16/22

Country: United States

Study design: Clinical trial and observational cohort with repeated measurements over time

Participant age range: Women aged 50-79 years at recruitment

Number of participants at baseline: 161,808

Year of initial enrollment: 1993-1998

Number of data collection waves: ~11 among various sub-cohorts

Measures of well-being:

  • Positive psychological well-being (overall /multidimensional)
  • Optimism
  • Social support / integration / cohesion

Quantity of well-being measures (e.g., number of constructs, number of times well-being was assessed): Moderate

Quality of well-being measures (e.g., were measures reliable and valid in the study population): Moderate

Measures of physical health: 

  • Self-rated / questionnaire-based health
  • Measured anthropometrics, e.g., weight
  • Adjudicated health outcomes

Access Information:

This dataset is available to all researchers.

Researchers must submit an application to access this data.

There are no fees required to access this dataset.

Notable citation:

Tindle H, Chang Y, Kuller L, Manson J, Robinson J, Rosal M, Siegle G & Matthews K. (2009). Optimism, cynical hostility, and incident coronary heart disease and mortality in the Women’s Health Initiative. Circulation, 2009(120), 656-662.