Abigail is taking cues from Mycobacterium tuberculosis on what is important for its survival through studying genes under selection during infection. She is currently working towards understanding the effects of selection on a classic Mtb virulence system.
Eddie is interested in the role antibodies play during tuberculosis infection. He is taking biased and unbiased approaches to identify specific characteristics of the humoral immune response capable of modulating infection or disease.
Maia is interested in understanding what good host protection against tuberculosis challenge looks like. She is currently working on defining the role of lung epithelial and stromal cells in immune cell circuits and crosstalk after vaccination or tuberculosis infection using single-cell RNA sequencing. Maia’s work is in collaboration with her co-mentor Adam Haber.
Sydney is interested in understanding the effect of Mycobacterium tuberculosis functional genetic diversity on altered antibiotic sensitivity, host fitness, and patient outcomes.