Current Position:
Senior Regulatory Scientist, Medical Device/ Account Manager at Voisin Consulting Life Sciences
Postdoctoral Fellow:
2010-2012
Education:
Ph.D., 2009, University of Geneva, Switzerland
Publications:
Zbinden M, Duquet A, Lorente-Trigos A, Ngwabyt SN, Borges I, Ruiz i Altaba A.; NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53. EMBO J. 2010; 29(15):2659-74. PMID: 20581802
Varnat F, Duquet A, Malerba M, Zbinden M, Mas C, Gervaz P, Ruiz i Altaba A. Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion. EMBO Mol Med. 2009; 1(6-7):338-51. PMID: 20049737
De Toni A, Zbinden M, Epstein JA, Ruiz i Altaba A, Prochiantz A, Caillé I.; Regulation of survival in adult hippocampal and glioblastoma stem cell lineages by the homeodomain-only protein HOP. Neural Dev. 2008; 3:13. PMID: 18507846
Stecca B, Mas C, Clement V, Zbinden M, Correa R, Piguet V, Beermann F, Ruiz I Altaba A. Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways. Proc Natl Acad Sci U S A. 2007; 104(14):5895-900. PMID: 17392427
Mathe Z, Dupraz P, Rinsch C, Thorens B, Bosco D, Zbinden M, Morel P, Berney T, Pepper MS. Tetracycline-regulated expression of VEGF-A in beta cells induces angiogenesis: improvement of engraftment following transplantation. Cell Transplant. 2006; 15(7):621-36. PMID: 17176614