Doctoral Student:
2020 –
Education:
B.S., 2018, Tulane University
M.S., 2020, University of Illinois at Urbana-Champaign
Research Interest:
Samuel focuses on discovering the mechanisms underlying how skeletal muscle balances protein and carbohydrate metabolism to contribute to overall metabolic homeostasis. Specifically, he is investigating how the tuberous sclerosis complex (TSC) subunit 2 (TSC2) acts as a switchboard to balance upstream signals such as insulin into outputs such as protein synthesis and glucose uptake and storage. By studying this pathway in skeletal muscle, we may uncover treatments for disorders in skeletal muscle function as well as broader metabolic disorders.
List of Publications:
Wu YF*, Lapp S*, Dvoretskiy S, Garcia G, Kim M, Tannehill A, Daniels L, Boppart MD. Optimization of a pericyte therapy to improve muscle recovery after limb immobilization. J Appl Physiol (1985). 2022 Apr 1;132(4):1020-1030. doi: 10.1152/japplphysiol.00700.2021. Epub 2022 Feb 17. PMID: 35175105; PMCID: PMC8993526. *equal contribution
Garg K, Mahmassani ZS, Dvoretskiy S, Valero MC, Huntsman HD, Lapp S, Wu YF, Hauschka SD, Burkin DJ, Boppart MD. Laminin-111 Improves the Anabolic Response to Mechanical Load in Aged Skeletal Muscle. J Gerontol A Biol Sci Med Sci. 2021 Mar 31;76(4):586-590. doi: 10.1093/gerona/glaa308. PMID: 33284954; PMCID: PMC8011696.