Identification of a small-molecule inhibitor that selectively blocks DNA-binding by Trypanosoma brucei replication protein A1.
Mukherjee A, Hossain Z, Erben E, Ma S, Choi JY, Kim HS.
Nat Commun. 2023 07 20. 14(1):4390. PMID: 37474515
Research Fellows
Aditi Mukherjee
Links
Overview
Ph.D., 09/2019, Host-pathogen interactions in Leishmania major
CSIR Indian Institute of Chemical Biology, Kolkata, India
Postdoctoral Researcher, 11/2023, Drug development against Trypanosoma brucei
Rutgers University, Newark
CSIR NET JRF and SRF
CSIR
GATE
IIT Bombay
Bibliography
Glyceraldehyde-3-phosphate dehydrogenase present in extracellular vesicles from Leishmania major suppresses host TNF-alpha expression.
Das P, Mukherjee A, Adak S.
J Biol Chem. 2021 10. 297(4):101198. PMID: 34534548
Regulation of Leishmania major PAS domain-containing phosphoglycerate kinase by cofactor Mg2+ ion at neutral pH.
Biswas S, Adhikari A, Mukherjee A, Das S, Adak S.
FEBS J. 2020 12. 287(23):5183-5195. PMID: 32196942
PAS domain-containing phosphoglycerate kinase deficiency in Leishmania major results in increased autophagosome formation and cell death.
Adhikari A, Biswas S, Mukherjee A, Das S, Adak S.
Biochem J. 2019 04 30. 476(8):1303-1321. PMID: 30988012
Loss of virulence in NAD(P)H cytochrome b5 oxidoreductase deficient Leishmania major.
Mukherjee A, Adhikari A, Das P, Biswas S, Mukherjee S, Adak S.
Biochem Biophys Res Commun. 2018 09 03. 503(1):371-377. PMID: 29906460
Control of catalysis in globin coupled adenylate cyclase by a globin-B domain.
Roy J, Sen Santara S, Adhikari A, Mukherjee A, Adak S.
Arch Biochem Biophys. 2015 Aug 01. 579:85-90. PMID: 26095616