Inhibition of malaria and babesiosis parasites by putative red blood cell targeting small molecules.
Groomes PV, Paul AS, Duraisingh MT.
Front Cell Infect Microbiol. 2024. 14:1304839. PMID: 38572319
Research Scientists
Aditya Shankar Paul
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Comparative chemical genomics in Babesia species identifies the alkaline phosphatase PhoD as a determinant of antiparasitic resistance.
Keroack CD, Elsworth B, Tennessen JA, Paul AS, Hua R, Ramirez-Ramirez L, Ye S, Moreira CK, Meyers MJ, Zarringhalam K, Duraisingh MT.
Proc Natl Acad Sci U S A. 2024 Feb 27. 121(9):e2312987121. PMID: 38377214
Comparative chemical genomics in Babesia species identifies the alkaline phosphatase phoD as a novel determinant of resistance.
Keroack CD, Elsworth B, Tennessen JA, Paul AS, Hua R, Ramirez-Ramirez L, Ye S, Moreira CM, Meyers MJ, Zarringhalam K, Duraisingh MT.
bioRxiv. 2023 Jun 13. PMID: 37398106
Babesia divergens egress from host cells is orchestrated by essential and druggable kinases and proteases.
Elsworth B, Keroack C, Rezvani Y, Paul A, Barazorda K, Tennessen J, Sack S, Moreira C, Gubbels MJ, Meyers M, Zarringhalam K, Duraisingh M.
Res Sq. 2023 Feb 28. PMID: 36909484
Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes.
Paul AS, Miliu A, Paulo JA, Goldberg JM, Bonilla AM, Berry L, Seveno M, Braun-Breton C, Kosber AL, Elsworth B, Arriola JSN, Lebrun M, Gygi SP, Lamarque MH, Duraisingh MT.
Nat Commun. 2020 07 15. 11(1):3532. PMID: 32669539
Fussing About Fission: Defining Variety Among Mainstream and Exotic Apicomplexan Cell Division Modes.
Gubbels MJ, Keroack CD, Dangoudoubiyam S, Worliczek HL, Paul AS, Bauwens C, Elsworth B, Engelberg K, Howe DK, Coppens I, Duraisingh MT.
Front Cell Infect Microbiol. 2020. 10:269. PMID: 32582569
Targeting Plasmodium Proteases to Block Malaria Parasite Escape and Entry.
Paul AS, Duraisingh MT.
Trends Parasitol. 2018 02. 34(2):95-97. PMID: 29269028
Host Cell Tropism and Adaptation of Blood-Stage Malaria Parasites: Challenges for Malaria Elimination.
Lim C, Dankwa S, Paul AS, Duraisingh MT.
Cold Spring Harb Perspect Med. 2017 Nov 01. 7(11). PMID: 28213436
PfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum.
Kumar S, Kumar M, Ekka R, Dvorin JD, Paul AS, Madugundu AK, Gilberger T, Gowda H, Duraisingh MT, Keshava Prasad TS, Sharma P.
Nat Commun. 2017 07 05. 8(1):63. PMID: 28680058
Erratum: Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony.
Ganter M, Goldberg JM, Dvorin JD, Paulo JA, King JG, Tripathi AK, Paul AS, Yang J, Coppens I, Jiang RH, Elsworth B, Baker DA, Dinglasan RR, Gygi SP, Duraisingh MT.
Nat Microbiol. 2017 Mar 06. 2:17038. PMID: 28263306