Brian Lawney

Modulation of circulating free testosterone fraction by testosterone, dihydrotestosterone, and estradiol during testosterone replacement therapy.

Jasuja R, Pencina KM, Lawney B, Stephens-Shields AJ, Ellenberg SS, Snyder PJ, Bhasin S.

Andrology. 2024 Aug 02. PMID: 39092887

Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study.

Pencina KM, Valderrabano R, Wipper B, Orkaby AR, Reid KF, Storer T, Lin AP, Merugumala S, Wilson L, Latham N, Ghattas-Puylara C, Ozimek NE, Cheng M, Bhargava A, Memish-Beleva Y, Lawney B, Lavu S, Swain PM, Apte RS, Sinclair DA, Livingston D, Bhasin S.

J Clin Endocrinol Metab. 2023 07 14. 108(8):1968-1980. PMID: 36740954

New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation.

Arwood ML, Liu Y, Harkins SK, Weinstock DM, Yang L, Stevenson KE, Plana OD, Dong J, Cirka H, Jones KL, Virtanen AT, Gupta DG, Ceas A, Lawney B, Yoda A, Leahy C, Hao M, He Z, Choi HG, Wang Y, Silvennoinen O, Hubbard SR, Zhang T, Gray NS, Li LS.

Cell Chem Biol. 2023 06 15. 30(6):618-631.e12. PMID: 37290440

Molecular design of the ?dT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing.

Mallis RJ, Duke-Cohan JS, Das DK, Akitsu A, Luoma AM, Banik D, Stephens HM, Tetteh PW, Castro CD, Krahnke S, Hussey RE, Lawney B, Brazin KN, Reche PA, Hwang W, Adams EJ, Lang MJ, Reinherz EL.

Proc Natl Acad Sci U S A. 2021 06 29. 118(26). PMID: 34172580

Estradiol induces allosteric coupling and partitioning of sex-hormone-binding globulin monomers among conformational states.

Jasuja R, Spencer D, Jayaraj A, Peng L, Krishna M, Lawney B, Patel P, Jayaram B, Thayer KM, Beveridge DL, Bhasin S.

iScience. 2021 Jun 25. 24(6):102414. PMID: 34041454

Allosterically Coupled Multisite Binding of Testosterone to Human Serum Albumin.

Jayaraj A, Schwanz HA, Spencer DJ, Bhasin S, Hamilton JA, Jayaram B, Goldman AL, Krishna M, Krishnan M, Shah A, Jin Z, Krenzel E, Nair SN, Ramesh S, Guo W, Wagner G, Arthanari H, Peng L, Lawney B, Jasuja R.

Endocrinology. 2021 02 01. 162(2). PMID: 33125473

Free testosterone and cardiometabolic parameters in men: comparison of algorithms.

Holmboe SA, Jasuja R, Lawney B, Priskorn L, Joergensen N, Linneberg A, Jensen TK, Skakkebæk NE, Juul A, Andersson AM.

Endocr Connect. 2021 Feb. 10(2):220-229. PMID: 33544092

Prolonged fasting drives a program of metabolic inflammation in human adipose tissue.

Fazeli PK, Zhang Y, O'Keefe J, Pesaresi T, Lun M, Lawney B, Steinhauser ML.

Mol Metab. 2020 12. 42:101082. PMID: 32992039

MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma.

Lietz CE, Garbutt C, Barry WT, Deshpande V, Chen YL, Lozano-Calderon SA, Wang Y, Lawney B, Ebb D, Cote GM, Duan Z, Hornicek FJ, Choy E, Petur Nielsen G, Haibe-Kains B, Quackenbush J, Spentzos D.

Sci Rep. 2020 03 10. 10(1):4409. PMID: 32157112

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer.

Zadra G, Ribeiro CF, Chetta P, Ho Y, Cacciatore S, Gao X, Syamala S, Bango C, Photopoulos C, Huang Y, Tyekucheva S, Bastos DC, Tchaicha J, Lawney B, Uo T, D'Anello L, Csibi A, Kalekar R, Larimer B, Ellis L, Butler LM, Morrissey C, McGovern K, Palombella VJ, Kutok JL, Mahmood U, Bosari S, Adams J, Peluso S, Dehm SM, Plymate SR, Loda M.

Proc Natl Acad Sci U S A. 2019 01 08. 116(2):631-640. PMID: 30578319