The Role of the Microbiome in the Etiopathogenesis of Colon Cancer.
El Tekle G, Andreeva N, Garrett WS.
Annu Rev Physiol. 2024 Feb 12. 86:453-478. PMID: 38345904
Research Fellows
Jennifer El Tekle
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Bacteria in cancer initiation, promotion and progression.
El Tekle G, Garrett WS.
Nat Rev Cancer. 2023 09. 23(9):600-618. PMID: 37400581
Co-occurrence and mutual exclusivity: what cross-cancer mutation patterns can tell us.
El Tekle G, Bernasocchi T, Unni AM, Bertoni F, Rossi D, Rubin MA, Theurillat JP.
Trends Cancer. 2021 09. 7(9):823-836. PMID: 34031014
Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer.
Bernasocchi T, El Tekle G, Bolis M, Mutti A, Vallerga A, Brandt LP, Spriano F, Svinkina T, Zoma M, Ceserani V, Rinaldi A, Janouskova H, Bossi D, Cavalli M, Mosole S, Geiger R, Dong Z, Yang CG, Albino D, Rinaldi A, Schraml P, Linder S, Carbone GM, Alimonti A, Bertoni F, Moch H, Carr SA, Zwart W, Kruithof-de Julio M, Rubin MA, Udeshi ND, Theurillat JP.
Nat Commun. 2021 02 02. 12(1):734. PMID: 33531470
De Novo Variants in SPOP Cause Two Clinically Distinct Neurodevelopmental Disorders.
Nabais Sá MJ, El Tekle G, de Brouwer APM, Sawyer SL, Del Gaudio D, Parker MJ, Kanani F, van den Boogaard MH, van Gassen K, Van Allen MI, Wierenga K, Purcarin G, Elias ER, Begtrup A, Keller-Ramey J, Bernasocchi T, van de Wiel L, Gilissen C, Venselaar H, Pfundt R, Vissers LELM, Theurillat JP, de Vries BBA.
Am J Hum Genet. 2020 03 05. 106(3):405-411. PMID: 32109420
Crystal structures of OrfX2 and P47 from a Botulinum neurotoxin OrfX-type gene cluster.
Gustafsson R, Berntsson RP, Martínez-Carranza M, El Tekle G, Odegrip R, Johnson EA, Stenmark P.
FEBS Lett. 2017 11. 591(22):3781-3792. PMID: 29067689
Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors.
Janouskova H, El Tekle G, Bellini E, Udeshi ND, Rinaldi A, Ulbricht A, Bernasocchi T, Civenni G, Losa M, Svinkina T, Bielski CM, Kryukov GV, Cascione L, Napoli S, Enchev RI, Mutch DG, Carney ME, Berchuck A, Winterhoff BJN, Broaddus RR, Schraml P, Moch H, Bertoni F, Catapano CV, Peter M, Carr SA, Garraway LA, Wild PJ, Theurillat JP.
Nat Med. 2017 09. 23(9):1046-1054. PMID: 28805821