IL-1Ra protects hematopoietic cells from chemotoxicity through p53-induced quiescence.
Ye H, Qian L, Zhu S, Deng S, Wang X, Zhu J, Chan GL, Yu Y, Han W.
FASEB J. 2019 11. 33(11):12135-12145. PMID: 31373847
Fellow or Post Doc
Gerald L. Chan
Distinguished Visiting Fellow
Division of Policy Translation and Leadership Development
Links
Bibliography
Progranulin Recruits HSP70 to ß-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease.
Jian J, Tian QY, Hettinghouse A, Zhao S, Liu H, Wei J, Grunig G, Zhang W, Setchell KDR, Sun Y, Overkleeft HS, Chan GL, Liu CJ.
EBioMedicine. 2016 Nov. 13:212-224. PMID: 27789271
Association Between Progranulin and Gaucher Disease.
Jian J, Zhao S, Tian QY, Liu H, Zhao Y, Chen WC, Grunig G, Torres PA, Wang BC, Zeng B, Pastores G, Tang W, Sun Y, Grabowski GA, Kong MX, Wang G, Chen Y, Liang F, Overkleeft HS, Saunders-Pullman R, Chan GL, Liu CJ.
EBioMedicine. 2016 Sep. 11:127-137. PMID: 27515686
Selective protection of normal cells during chemotherapy by RY4 peptides.
Wu XR, Liu L, Zhang ZF, Zhang B, Sun H, Chan GL, Li N.
Mol Cancer Res. 2014 Oct. 12(10):1365-76. PMID: 24874433
IL-1Ra selectively protects intestinal crypt epithelial cells, but not tumor cells, from chemotoxicity via p53-mediated upregulation of p21(WAF1) and p27(KIP1.).
Wang X, Zhu S, Qian L, Gao J, Wu M, Gao J, Zhang Y, Chan GL, Yu Y, Han W.
Pharmacol Res. 2014 Apr. 82:21-33. PMID: 24681512
A human monoclonal autoantibody to breast cancer identifies the PDZ domain containing protein GIPC1 as a novel breast cancer-associated antigen.
Rudchenko S, Scanlan M, Kalantarov G, Yavelsky V, Levy C, Estabrook A, Old L, Chan GL, Lobel L, Trakht I.
BMC Cancer. 2008 Aug 24. 8:248. PMID: 18721486