Research Scientists

Heather J. Ribaudo

Principal Research Scientist

Biostatistics

ribaudo@sdac.harvard.edu

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Catalyst Profile

Overview

Research

Heather Ribaudo (formerly Heather Beacon) is a Research Scientist at the Center for Biostatistics in AIDS Research (CBAR) and the Department of Biostatistics at Harvard University where she focuses on HIV and AIDS clinical trials research within the AIDS clinical Trials Group (ACTG). Dr. Ribaudo is also the Associate Director of the Biostatistics and Computational Biology core of the Harvard University CFAR.

Dr. Ribaudo received her Ph.D. from the Medical Statistics department of the London School of Hygiene and Tropical Medicine in 1996. Since joining CBAR as a post-doctoral fellow in 1997, Dr. Ribaudo has been involved in collaborative research in the HIV field and has been responsible for the design, monitoring, and analysis of many specific major NIAID-sponsored HIV clinical trials. Her research interests include the design and analysis of clinical trials in AIDS research particularly the choice, evaluation, and monitoring of surrogate endpoints, HIV-1 resistance, viral dynamics, and human genomics. She is also interested in the application of causal inference analysis for the estimation of treatment effects from observation data in HIV.

Bibliography

Associations of Muscle Density and Area With Coronary Artery Plaque and Physical Function.

Erlandson KM, Umbleja T, Lu MT, Taron J, Ribaudo HJ, Overton ET, Presti RM, Haas DW, Sax PE, Yin MT, Zhai BK, Louis R, Upadhyay N, Eslami P, Douglas PS, Zanni MV, Fitch KV, Fulda ES, Fichtenbaum CJ, Malvestutto CD, Grinspoon SK, Brown TT.

J Acquir Immune Defic Syndr. 2023 10 01. 94(2):174-184. PMID: 37368931

Biological and Clinical Implications of the Vascular Endothelial Growth Factor Coreceptor Neuropilin-1 in Human Immunodeficiency Virus.

Schnittman SR, Kolossváry M, Beck-Engeser G, Fitch KV, Ambayec GC, Nance RM, Zanni MV, Diggs M, Chan F, McCallum S, Toribio M, Bamford L, Fichtenbaum CJ, Eron JJ, Jacobson JM, Mayer KH, Malvestutto C, Bloomfield GS, Moore RD, Umbleja T, Saag MS, Aberg JA, Currier JS, Delaney JAC, Martin JN, Lu MT, Douglas PS, Ribaudo HJ, Crane HM, Hunt PW, Grinspoon SK.

Open Forum Infect Dis. 2023 Oct. 10(10):ofad467. PMID: 37869406

Hepatic steatosis and nonalcoholic fatty liver disease are common and associated with cardiometabolic risk in a primary prevention cohort of people with HIV.

Lake JE, Taron J, Ribaudo HJ, Leon-Cruz J, Utay NS, Swaminathan S, Fitch KV, Kileel EM, Paradis K, Fulda ES, Ho KS, Luetkemeyer AF, Johnston CD, Zanni MV, Douglas PS, Grinspoon SK, Lu MT, Fichtenbaum CJ.

AIDS. 2023 11 15. 37(14):2149-2159. PMID: 37503623

Pitavastatin to Prevent Cardiovascular Disease in HIV Infection.

Grinspoon SK, Fitch KV, Zanni MV, Fichtenbaum CJ, Umbleja T, Aberg JA, Overton ET, Malvestutto CD, Bloomfield GS, Currier JS, Martinez E, Roa JC, Diggs MR, Fulda ES, Paradis K, Wiviott SD, Foldyna B, Looby SE, Desvigne-Nickens P, Alston-Smith B, Leon-Cruz J, McCallum S, Hoffmann U, Lu MT, Ribaudo HJ, Douglas PS.

N Engl J Med. 2023 Aug 24. 389(8):687-699. PMID: 37486775

Pericoronary Adipose Tissue Density, Inflammation, and Subclinical Coronary Artery Disease Among People with HIV in the REPRIEVE Cohort.

Foldyna B, Mayrhofer T, Zanni MV, Lyass A, Barve R, Karady J, McCallum S, Burdo TH, Fitch KV, Paradis K, Fulda ES, Diggs MR, Bloomfield GS, Malvestutto CD, Fichtenbaum CJ, Aberg JA, Currier JS, Ribaudo HJ, Hoffmann U, Lu MT, Douglas PS, Grinspoon SK.

Clin Infect Dis. 2023 Jul 13. PMID: 37439633

Changes in Body Mass Index with Longer-term Integrase Inhibitor Use: A Longitudinal Analysis of Data from the Randomized Trial to Prevent Vascular Events in Human Immunodeficiency Virus (REPRIEVE).

Kileel EM, Malvestutto CD, Lo J, Fitch KV, Fichtenbaum CJ, Aberg JA, Zanni MV, Martinez E, Okeke NL, Kumar P, Joao E, Bares SH, Berrner D, Smieja M, Roa JC, McCallum S, Douglas PS, Ribaudo HJ, Grinspoon SK.

Clin Infect Dis. 2023 Jun 08. 76(11):2010-2013. PMID: 36825498

Identification of pre-infection markers and differential plasma protein expression following SARS-CoV-2 infection in people living with HIV.

Kolossváry M, deFilippi C, McCallum S, Fitch KV, Diggs MR, Fulda ES, Ribaudo HJ, Fichtenbaum CJ, Aberg JA, Malvestutto CD, Currier JS, Casado JL, Gutiérrez F, Sereti I, Douglas PS, Zanni MV, Grinspoon SK.

EBioMedicine. 2023 Apr. 90:104538. PMID: 36966617

Effect of host factors and COVID-19 infection on the humoral immune repertoire in treated HIV.

Schnittman SR, Jung W, Fitch KV, Zanni MV, McCallum S, Lee JS, Shin S, Davis BJ, Fulda ES, Diggs MR, Giguel F, Chinchay R, Sheth AN, Fichtenbaum CJ, Malvestutto C, Aberg JA, Currier J, Lauffenburger DA, Douglas PS, Ribaudo HJ, Alter G, Grinspoon SK.

JCI Insight. 2023 03 08. 8(5). PMID: 36805331

Coronary Artery Plaque Composition and Severity Relate to the Inflammasome in People With Treated Human Immunodeficiency Virus.

Schnittman SR, Kitch DW, Swartz TH, Burdo TH, Fitch KV, McCallum S, Flynn JM, Fulda ES, Diggs MR, Stapleton JT, Casado JL, Taron J, Currier JS, Zanni MV, Malvestutto C, Fichtenbaum CJ, Aberg JA, Ribaudo HJ, Lu MT, Douglas PS, Grinspoon SK.

Open Forum Infect Dis. 2023 Mar. 10(3):ofad106. PMID: 36998633

Cytomegalovirus Immunoglobulin G (IgG) Titer and Coronary Artery Disease in People With Human Immunodeficiency Virus (HIV).

Schnittman SR, Lu MT, Mayrhofer T, Burdo TH, Fitch KV, McCallum S, Fulda ES, Zanni MV, Foldyna B, Malvestutto C, Fichtenbaum CJ, Aberg JA, Bloomfield GS, Overton ET, Currier J, Tebas P, Sha BE, Ribaudo HJ, Flynn JM, Douglas PS, Erlandson KM, Grinspoon SK.

Clin Infect Dis. 2023 02 08. 76(3):e613-e621. PMID: 35975297

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