Maria Mota

A spatiotemporally resolved single-cell atlas of the Plasmodium liver stage.

Afriat A, Zuzarte-Luís V, Bahar Halpern K, Buchauer L, Marques S, Chora ÂF, Lahree A, Amit I, Mota MM, Itzkovitz S.

Nature. 2022 Nov. 611(7936):563-569. PMID: 36352220

Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance.

Tye MA, Payne NC, Johansson C, Singh K, Santos SA, Fagbami L, Pant A, Sylvester K, Luth MR, Marques S, Whitman M, Mota MM, Winzeler EA, Lukens AK, Derbyshire ER, Oppermann U, Wirth DF, Mazitschek R.

Nat Commun. 2022 08 25. 13(1):4976. PMID: 36008486

Host lung microbiota promotes malaria-associated acute respiratory distress syndrome.

Mukherjee D, Chora ÂF, Lone JC, Ramiro RS, Blankenhaus B, Serre K, Ramirez M, Gordo I, Veldhoen M, Varga-Weisz P, Mota MM.

Nat Commun. 2022 06 29. 13(1):3747. PMID: 35768411

Active APPL1 sequestration by Plasmodium favors liver-stage development.

Lahree A, Baptista SJS, Marques S, Perschin V, Zuzarte-Luís V, Goel M, Choudhary HH, Mishra S, Stigloher C, Zerial M, Sundaramurthy V, Mota MM.

Cell Rep. 2022 05 31. 39(9):110886. PMID: 35649358

Plasmodium parasitophorous vacuole membrane-resident protein UIS4 manipulates host cell actin to avoid parasite elimination.

M'Bana V, Lahree A, Marques S, Slavic K, Mota MM.

iScience. 2022 May 20. 25(5):104281. PMID: 35573190

The reciprocal influence of the liver and blood stages of the malaria parasite's life cycle.

Chora ÂF, Mota MM, Prudêncio M.

Int J Parasitol. 2022 10. 52(11):711-715. PMID: 35367213

Disrupting Plasmodium UIS3-host LC3 interaction with a small molecule causes parasite elimination from host cells.

Setua S, Enguita FJ, Chora ÂF, Ranga-Prasad H, Lahree A, Marques S, Sundaramurthy V, Mota MM.

Commun Biol. 2020 11 19. 3(1):688. PMID: 33214643

Plasmodium translocon component EXP2 facilitates hepatocyte invasion.

Mello-Vieira J, Enguita FJ, de Koning-Ward TF, Zuzarte-Luís V, Mota MM.

Nat Commun. 2020 11 06. 11(1):5654. PMID: 33159090

A Novel Chemically Differentiated Mouse Embryonic Stem Cell-Based Model to Study Liver Stages of Plasmodium berghei.

Tripathi J, Segeritz CP, Griffiths G, Bushell W, Vallier L, Skarnes WC, Mota MM, Billker O.

Stem Cell Reports. 2020 06 09. 14(6):1123-1134. PMID: 32442532

Targeting liver stage malaria with metformin.

Vera IM, Grilo Ruivo MT, Lemos Rocha LF, Marques S, Bhatia SN, Mota MM, Mancio-Silva L.

JCI Insight. 2019 12 19. 4(24). PMID: 31852843