Integrative analysis of transcriptomic and epigenomic data reveals distinct patterns for developmental and housekeeping gene regulation.
Abnizova I, Stapel C, Boekhorst RT, Lee JTH, Hemberg M.
BMC Biol. 2024 Apr 10. 22(1):78. PMID: 38600550
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Joint analysis of mutational and transcriptional landscapes in human cancer reveals key perturbations during cancer evolution.
Cho JW, Cao J, Hemberg M.
Genome Biol. 2024 Mar 08. 25(1):65. PMID: 38459554
MEA-NAP compares microscale functional connectivity, topology, and network dynamics in organoid or monolayer neuronal cultures.
Sit TP, Feord RC, Dunn AW, Chabros J, Oluigbo D, Smith HH, Burn L, Chang E, Boschi A, Yuan Y, Gibbons GM, Khayat-Khoei M, De Angelis F, Hemberg E, Hemberg M, Lancaster MA, Lakatos A, Eglen SJ, Paulsen O, Mierau SB.
bioRxiv. 2024 Mar 03. PMID: 38370637
Author Correction: Integrative single-cell characterization of a frugivorous and an insectivorous bat kidney and pancreas.
Gordon WE, Baek S, Nguyen HP, Kuo YM, Bradley R, Fong SL, Kim N, Galazyuk A, Lee I, Ingala MR, Simmons NB, Schountz T, Cooper LN, Georgakopoulos-Soares I, Hemberg M, Ahituv N.
Nat Commun. 2024 Feb 27. 15(1):1777. PMID: 38413559
Single-cell and spatial transcriptomics: Bridging current technologies with long-read sequencing.
Yuan CU, Quah FX, Hemberg M.
Mol Aspects Med. 2024 04. 96:101255. PMID: 38368637
Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model.
Wang Y, Cho JW, Kastrunes G, Buck A, Razimbaud C, Culhane AC, Sun J, Braun DA, Choueiri TK, Wu CJ, Jones K, Nguyen QD, Zhu Z, Wei K, Zhu Q, Signoretti S, Freeman GJ, Hemberg M, Marasco WA.
iScience. 2024 Feb 16. 27(2):108879. PMID: 38327771
Integrative single-cell characterization of a frugivorous and an insectivorous bat kidney and pancreas.
Gordon WE, Baek S, Nguyen HP, Kuo YM, Bradley R, Fong SL, Kim N, Galazyuk A, Lee I, Ingala MR, Simmons NB, Schountz T, Cooper LN, Georgakopoulos-Soares I, Hemberg M, Ahituv N.
Nat Commun. 2024 Jan 09. 15(1):12. PMID: 38195585
Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2a axis.
Suh J, Kim H, Min J, Yeon HJ, Hemberg M, Scimeca L, Wu MR, Kang HG, Kim YJ, Kim JH.
Cell Rep Med. 2024 01 16. 5(1):101342. PMID: 38128534
Predicting the impact of sequence motifs on gene regulation using single-cell data.
Hepkema J, Lee NK, Stewart BJ, Ruangroengkulrith S, Charoensawan V, Clatworthy MR, Hemberg M.
Genome Biol. 2023 08 15. 24(1):189. PMID: 37582793
Therapy-associated remodeling of pancreatic cancer revealed by single-cell spatial transcriptomics and optimal transport analysis.
Shiau C, Cao J, Gregory MT, Gong D, Yin X, Cho JW, Wang PL, Su J, Wang S, Reeves JW, Kim TK, Kim Y, Guo JA, Lester NA, Schurman N, Barth JL, Weissleder R, Jacks T, Qadan M, Hong TS, Wo JY, Roberts H, Beechem JM, Castillo CF, Mino-Kenudson M, Ting DT, Hemberg M, Hwang WL.
bioRxiv. 2023 Jun 29. PMID: 37425692