Mild mitochondrial impairment enhances innate immunity and longevity through ATFS-1 and p38 signaling.
Campos JC, Wu Z, Rudich PD, Soo SK, Mistry M, Ferreira JC, Blackwell TK, Van Raamsdonk JM.
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Activation of mitochondrial unfolded protein response protects against multiple exogenous stressors.
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Life Sci Alliance. 2021 Dec. 4(12). PMID: 34583931
Drosophila Fezf functions as a transcriptional repressor to direct layer-specific synaptic connectivity in the fly visual system.
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Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.
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A computationally inspired in-vivo approach identifies a link between amygdalar transcriptional heterogeneity, socialization and anxiety.
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Supporting Single Cell RNA-seq Analysis at Harvard - A Community Approach.
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Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans.
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Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression.
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The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position.
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A Milieu Molecule for TGF-ß Required for Microglia Function in the Nervous System.
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