Professor of Molecular Immunology, Emeritus
Immunology and Infectious Diseases
Dr. Grusby's research interests have been on the role of a class of transcription factors called signal transducer and activator of transcription (STATs) in the differentiation and function of T helper cell subsets. Studies from his lab have shown how manipulating STAT activity can alter the function of T helper cells and therefore change the outcome of conditions such as asthma and other inflammatory diseases. In addition, Dr. Grusby has published a number of studies on the biology of the cytokine IL-21, demonstrating its critical role in the development of diabetes. Dr. Grusby served as the past Director of the PhD in Biological Sciences in Public Health (BPH) Program within the Division of Biological Sciences and as a member of the Steering Committee for the Office for Educational Programs.
Ph.D, 1988
Northwestern University
Cao D, Ma X, Cai J, Luan J, Liu AJ, Yang R, Cao Y, Zhu X, Zhang H, Chen YX, Shi Y, Shi GX, Zou D, Cao X, Grusby MJ, Xie Z, Zhang WJ.
Nat Commun. 2016 Apr 15. 7:11121. PMID: 27079169
Lajoie S, Lewkowich I, Herman NS, Sproles A, Pesce JT, Wynn TA, Grusby MJ, Hamid Q, Wills-Karp M.
Clin Exp Allergy. 2014 Jul. 44(7):976-85. PMID: 24807637
Sutherland AP, Joller N, Michaud M, Liu SM, Kuchroo VK, Grusby MJ.
J Immunol. 2013 Apr 15. 190(8):3977-84. PMID: 23479229
Qu Z, Fu J, Ma H, Zhou J, Jin M, Mapara MY, Grusby MJ, Xiao G.
Cell Biosci. 2012 Jun 25. 2(1):23. PMID: 22731402
Zhang Y, Xie Z, Zhou L, Li L, Zhang H, Zhou G, Ma X, Herrera PL, Liu Z, Grusby MJ, Zhang WJ.
Gastroenterology. 2012 Jun. 142(7):1571-1580.e6. PMID: 22374165
Tanaka T, Yamamoto Y, Muromoto R, Ikeda O, Sekine Y, Grusby MJ, Kaisho T, Matsuda T.
Sci Signal. 2011 Dec 06. 4(202):ra85. PMID: 22155789
Qu Z, Yan P, Fu J, Jiang J, Grusby MJ, Smithgall TE, Xiao G.
Cancer Res. 2010 Mar 01. 70(5):1766-72. PMID: 20145149
Fathman JW, Gurish MF, Hemmers S, Bonham K, Friend DS, Grusby MJ, Glimcher LH, Mowen KA.
Proc Natl Acad Sci U S A. 2010 Feb 23. 107(8):3663-8. PMID: 20133688
Hiramatsu Y, Suto A, Kashiwakuma D, Kanari H, Kagami S, Ikeda K, Hirose K, Watanabe N, Grusby MJ, Iwamoto I, Nakajima H.
J Leukoc Biol. 2010 Apr. 87(4):703-12. PMID: 20042469
Sutherland AP, Zhang H, Zhang Y, Michaud M, Xie Z, Patti ME, Grusby MJ, Zhang WJ.
Mol Cell Biol. 2009 May. 29(10):2804-15. PMID: 19273596
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