Professor of Immunology and Infectious Diseases
Immunology and Infectious Diseases
Dr. Sabeti's lab focuses on developing new analytical and genomic methods to study evolutionary adaptation and genetic diversity in humans and pathogens, with three current research foci: (1) Identifying and characterizing the underlying adaptive changes that have shaped the human species over time; and (2) Investigating genetic diversity in pathogens such as Lassa virus, Ebola virus, Zika virus, and Babesia microti, towards improved diagnostics, surveillance, and interventions, and (3) Developing novels tools to detect and diagnose microbes causing human morbidity and mortality.
Dr. Sabeti's computational genomic lab has contributed to widely varying fields — including human evolutionary biology, gene therapy, microbial sequencing, information theory, and disease surveillance. They aim to create comprehensive approaches for detecting, containing, and treating deadly infectious diseases, including Lassa virus, Ebola virus, Zika virus, and SARS-CoV-2. She has invested in capacity building and education throughout, co-founding the African Center for Excellence of Genomic of Infectious Disease, enabling the first diagnosis of Ebola in Sierra Leone and Nigeria, training thousands of scientists through extended educational programs, and establishing genome centers in West Africa.
B.S., 1997
M.I.T.
M.Sc., 1998
University of Oxford
D.Phil., 2003
University of Oxford
M.D., 2006
Harvard Medical School
Normandin E, Valizadeh N, Rudmann EA, Uddin R, Dobbins ST, MacInnis BL, Padera RF, Siddle KJ, Lemieux JE, Sabeti PC, Mukerji SS, Solomon IH.
J Neuropathol Exp Neurol. 2023 Mar 20. 82(4):283-295. PMID: 36847705
Turbett SE, Tomkins-Tinch CH, Anahtar MN, Dugdale CM, Hyle EP, Shenoy ES, Shaw B, Egbuonu K, Bowman KA, Zachary KC, Adams GC, Hooper DC, Ryan ET, LaRocque RC, Bassett IV, Triant VA, Siddle KJ, Rosenberg E, Sabeti PC, Schaffner SF, MacInnis BL, Lemieux JE, Charles RC.
Clin Infect Dis. 2023 03 04. 76(5):850-860. PMID: 36268576
Lemieux JE, Huang W, Hill N, Cerar T, Freimark L, Hernandez S, Luban M, Maraspin V, Bogovic P, Ogrinc K, Ruzic-Sabljic E, Lapierre P, Lasek-Nesselquist E, Singh N, Iyer R, Liveris D, Reed KD, Leong JM, Branda JA, Steere AC, Wormser GP, Strle F, Sabeti PC, Schwartz I, Strle K.
bioRxiv. 2023 Feb 27. PMID: 36909473
Adams G, Moreno GK, Petros BA, Uddin R, Levine Z, Kotzen B, Messer KS, Dobbins ST, DeRuff KC, Loreth CM, Brock-Fisher T, Schaffner SF, Chaluvadi S, Kanjilal S, Luban J, Ozonoff A, Park DJ, Turbett SE, Siddle KJ, MacInnis BL, Sabeti PC, Lemieux JE.
N Engl J Med. 2023 Feb 22. PMID: 36812457
Patel T, Hammond A, Nasari A, Sani K, Dee EC, Jain B, Sabeti PC.
Nat Med. 2023 Feb 20. PMID: 36806790
Olawoye IB, Oluniyi PE, Oguzie JU, Uwanibe JN, Kayode TA, Olumade TJ, Ajogbasile FV, Parker E, Eromon PE, Abechi P, Sobajo TA, Ugwu CA, George UE, Ayoade F, Akano K, Oyejide NE, Nosamiefan I, Fred-Akintunwa I, Adedotun-Sulaiman K, Brimmo FB, Adegboyega BB, Philip C, Adeleke RA, Chukwu GC, Ahmed MI, Ope-Ewe OO, Otitoola SG, Ogunsanya OA, Saibu MF, Sijuwola AE, Ezekiel GO, John OG, Akin-John JO, Akinlo OO, Fayemi OO, Ipaye TO, Nwodo DC, Omoniyi AE, Omwanghe IB, Terkuma CA, Okolie J, Ayo-Ale O, Ikponmwosa O, Benevolence E, Naregose GO, Patience AE, Blessing O, Micheal A, Jacqueline A, Aiyepada JO, Ebhodaghe P, Racheal O, Rita E, Rosemary GE, Solomon E, Anieno E, Edna Y, Chris AO, Donatus AI, Ogbaini-Emovon E, Tatfeng MY, Omunakwe HE, Bob-Manuel M, Ahmed RA, Onwuamah CK, Shaibu JO, Okwuraiwe A, Ataga AE, Bock-Oruma A, Daramola F, Yusuf IF, Fajola A, Ntia NA, Ekpo JJ, Moses AE, Moore-Igwe BW, Fakayode OE, Akinola M, Kida IM, Oderinde BS, Wudiri ZW, Adeyemi OO, Akanbi OA, Ahumibe A, Akinpelu A, Ayansola O, Babatunde O, Omoare AA, Chukwu C, Mba NG, Omoruyi EC, Olisa O, Akande OK, Nwafor IE, Ekeh MA, Ndoma E, Ewah RL, Duruihuoma RO, Abu A, Odeh E, Onyia V, Ojide CK, Okoro S, Igwe D, Ogah EO, Khan K, Ajayi NA, Ugwu CN, Ukwaja KN, Ugwu NI, Abejegah C, Adedosu N, Ayodeji O, Liasu AA, Isamotu RO, Gadzama G, Petros BA, Siddle KJ, Schaffner SF, Akpede G, Erameh CO, Baba MM, Oladiji F, Audu R, Ndodo N, Fowotade A, Okogbenin S, Okokhere PO, Park DJ, Mcannis BL, Adetifa IM, Ihekweazu C, Salako BL, Tomori O, Happi AN, Folarin OA, Andersen KG, Sabeti PC, Happi CT.
Nat Commun. 2023 02 13. 14(1):811. PMID: 36781860
Petros BA, Turcinovic J, Welch NL, White LF, Kolaczyk ED, Bauer MR, Cleary M, Dobbins ST, Doucette-Stamm L, Gore M, Nair P, Nguyen TG, Rose S, Taylor BP, Tsang D, Wendlandt E, Hope M, Platt JT, Jacobson KR, Bouton T, Yune S, Auclair JR, Landaverde L, Klapperich CM, Hamer DH, Hanage WP, MacInnis BL, Sabeti PC, Connor JH, Springer M.
Clin Infect Dis. 2023 02 08. 76(3):e400-e408. PMID: 35616119
Normandin E, Rudy M, Barkas N, Schaffner SF, Levine Z, Padera RF, Babadi M, Mukerji SS, Park DJ, MacInnis BL, Siddle KJ, Sabeti PC, Solomon IH.
Nat Commun. 2023 02 02. 14(1):574. PMID: 36732505
McMinn RJ, Langsjoen RM, Bombin A, Robich RM, Ojeda E, Normandin E, Goethert HK, Lubelczyk CB, Schneider E, Cosenza D, Meagher M, Prusinski MA, Sabeti PC, Smith RP, Telford SR, Piantadosi A, Ebel GD.
Virus Evol. 2023. 9(1):vead008. PMID: 36846826
Adams G, Moreno GK, Petros BA, Uddin R, Levine Z, Kotzen B, Messer K, Dobbins ST, DeRuff KC, Loreth C, Brock-Fisher T, Schaffner SF, Chaluvadi S, Kanjilal S, Luban J, Ozonoff A, Park D, Turbett S, Siddle KJ, MacInnis BL, Sabeti P, Lemieux J.
medRxiv. 2023 Jan 05. PMID: 36656774
Scientists have developed a machine learning model that can predict which SARS-CoV-2 viral variants are likely to cause surges in COVID-19 cases.
A collaboration between Colorado Mesa University and the Broad Institute of M.I.T. and Harvard has yielded “the most sophisticated system in the country to track outbreaks” of COVID-19, according Pardis Sabeti, a professor of immunology and infectious diseases…
Companies, universities, and other large organizations and institutions that are conducting regular COVID-19 testing among their members should consider expanding their testing efforts to nearby communities to better control the spread of the virus, according to new research…
Many African nations are extremely vulnerable to infectious disease outbreaks, including Ebola, Lassa fever, Zika, and West Nile virus. A March 17, 2021, Wired article looked at the joint effort of two scientists—Christian Happi and Pardis Sabeti—to develop…
Two Harvard T.H. Chan School of Public Health faculty members, Marc Lipsitch and Pardis Sabeti, have been elected to the National Academy of Medicine.
