Peter H Culviner

Tuberculosis treatment failure associated with evolution of antibiotic resilience.

Liu Q, Zhu J, Dulberger CL, Stanley S, Wilson S, Chung ES, Wang X, Culviner P, Liu YJ, Hicks ND, Babunovic GH, Giffen SR, Aldridge BB, Garner EC, Rubin EJ, Chao MC, Fortune SM.

Science. 2022 12 09. 378(6624):1111-1118. PMID: 36480634

An ADP-ribosyltransferase toxin kills bacterial cells by modifying structured non-coding RNAs.

Bullen NP, Sychantha D, Thang SS, Culviner PH, Rudzite M, Ahmad S, Shah VS, Filloux A, Prehna G, Whitney JC.

Mol Cell. 2022 09 15. 82(18):3484-3498.e11. PMID: 36070765

Escherichia coli SymE is a DNA-binding protein that can condense the nucleoid.

Thompson MK, Nocedal I, Culviner PH, Zhang T, Gozzi KR, Laub MT.

Mol Microbiol. 2022 04. 117(4):851-870. PMID: 34964191

Global Analysis of the Specificities and Targets of Endoribonucleases from Escherichia coli Toxin-Antitoxin Systems.

Culviner PH, Nocedal I, Fortune SM, Laub MT.

mBio. 2021 10 26. 12(5):e0201221. PMID: 34544284

Mutations in dnaA and a cryptic interaction site increase drug resistance in Mycobacterium tuberculosis.

Hicks ND, Giffen SR, Culviner PH, Chao MC, Dulberger CL, Liu Q, Stanley S, Brown J, Sixsmith J, Wolf ID, Fortune SM.

PLoS Pathog. 2020 11. 16(11):e1009063. PMID: 33253310

Stress Can Induce Transcription of Toxin-Antitoxin Systems without Activating Toxin.

LeRoux M, Culviner PH, Liu YJ, Littlehale ML, Laub MT.

Mol Cell. 2020 07 16. 79(2):280-292.e8. PMID: 32533919

A Simple, Cost-Effective, and Robust Method for rRNA Depletion in RNA-Sequencing Studies.

Culviner PH, Guegler CK, Laub MT.

mBio. 2020 04 21. 11(2). PMID: 32317317

Global Analysis of the E. coli Toxin MazF Reveals Widespread Cleavage of mRNA and the Inhibition of rRNA Maturation and Ribosome Biogenesis.

Culviner PH, Laub MT.

Mol Cell. 2018 06 07. 70(5):868-880.e10. PMID: 29861158

Electrostatic effect of the ribosomal surface on nascent polypeptide dynamics.

Knight AM, Culviner PH, Kurt-Yilmaz N, Zou T, Ozkan SB, Cavagnero S.

ACS Chem Biol. 2013. 8(6):1195-204. PMID: 23517476

Production of ribosome-released nascent proteins with optimal physical properties.

Ziehr DR, Ellis JP, Culviner PH, Cavagnero S.

Anal Chem. 2010 Jun 01. 82(11):4637-43. PMID: 20397641