Shijun Deng

Atherosclerosis-associated hepatic secretion of VLDL but not PCSK9 is dependent on cargo receptor protein Surf4.

Wang B, Shen Y, Zhai L, Xia X, Gu HM, Wang M, Zhao Y, Chang X, Alabi A, Xing S, Deng S, Liu B, Wang G, Qin S, Zhang DW.

J Lipid Res. 2021. 62:100091. PMID: 34118252

Membrane type 1 matrix metalloproteinase promotes LDL receptor shedding and accelerates the development of atherosclerosis.

Alabi A, Xia XD, Gu HM, Wang F, Deng SJ, Yang N, Adijiang A, Douglas DN, Kneteman NM, Xue Y, Chen L, Qin S, Wang G, Zhang DW.

Nat Commun. 2021 03 25. 12(1):1889. PMID: 33767172

The role of the C-terminal domain of PCSK9 and SEC24 isoforms in PCSK9 secretion.

Deng SJ, Shen Y, Gu HM, Guo S, Wu SR, Zhang DW.

Biochim Biophys Acta Mol Cell Biol Lipids. 2020 06. 1865(6):158660. PMID: 32058034

Surf4 regulates expression of proprotein convertase subtilisin/kexin type 9 (PCSK9) but is not required for PCSK9 secretion in cultured human hepatocytes.

Shen Y, Wang B, Deng S, Zhai L, Gu HM, Alabi A, Xia X, Zhao Y, Chang X, Qin S, Zhang DW.

Biochim Biophys Acta Mol Cell Biol Lipids. 2020 02. 1865(2):158555. PMID: 31676436

Identification of amino acid residues in the ligand binding repeats of LDL receptor important for PCSK9 binding.

Deng SJ, Alabi A, Gu HM, Adijiang A, Qin S, Zhang DW.

J Lipid Res. 2019 03. 60(3):516-527. PMID: 30617148

Identification of an Amino Acid Residue Critical for Plasma Membrane Localization of ATP-Binding Cassette Transporter G1--Brief Report.

Gu HM, Wang F, Alabi A, Deng S, Qin S, Zhang DW.

Arterioscler Thromb Vasc Biol. 2016 Feb. 36(2):253-5. PMID: 26695502