Machine and Deep Learning in Molecular and Genetic Aspects of Sleep Research.
Elgart M, Redline S, Sofer T.
Neurotherapeutics. 2021 Apr 07. PMID: 33829409
Assistant Professor of Medicine
Medicine
Brigham and Women's Hospital
I am a biostatistical researcher focusing on genetic and omics analyses of diverse and complex populations. I did my PhD in Biostatistics at the Harvard T.H. Chan School of Public Health, and graduated at 2012. Then, I continued as a postdoctoral fellow there, and later became a research scientist at the Genetic Analysis Center at the University of Washington in Seattle. At UW, I worked on genetic association analyses in the Hispanic Community Health Study/Study of Latinos, and on analysis of whole genome sequencing data from the NHLBI's Trans-Omics in Precision Medicine initiative. In late 2017 I moved to BWH and Harvard University, where I continue to develop and implement methodology for genetic and omics analyses of sleep , cognitive, cardiopulmonary, and metabolic phenotypes, with the goal of understanding the genetic basis of such phenotypes, and how environmental exposures modify the pathways from genotypes to phenotypes. I extensively collaborate with minority population studies such as the Hispanic Community Health Study/Study of Latinos, the Multi-Ethnic Study of Atherosclerosis, the Jackson Heart Study, and more.
Elgart M, Redline S, Sofer T.
Neurotherapeutics. 2021 Apr 07. PMID: 33829409
Khoury S, Wang QP, Parisien M, Gris P, Bortsov AV, Linnstaedt SD, McLean SA, Tungate AS, Sofer T, Lee J, Louie T, Redline S, Kaunisto MA, Kalso EA, Munter HM, Nackley AG, Slade GD, Smith SB, Zaykin DV, Fillingim RB, Ohrbach R, Greenspan JD, Maixner W, Neely GG, Diatchenko L.
Sleep. 2021 Mar 12. 44(3). PMID: 33034629
Li X, Sotres-Alvarez D, Gallo LC, Ramos AR, Aviles-Santa L, Perreira KM, Isasi CR, Zee PC, Savin KL, Schneiderman N, Wassertheil-Smoller S, Sofer T, Daviglus M, Redline S.
Am J Respir Crit Care Med. 2021 02 01. 203(3):356-365. PMID: 32758008
Azarbarzin A, Sands SA, Younes M, Taranto-Montemurro L, Sofer T, Vena D, Alex RM, Kim SW, Gottlieb DJ, White DP, Redline S, Wellman A.
Am J Respir Crit Care Med. 2021 Jan 06. PMID: 33406013
Borker PV, Reid M, Sofer T, Butler MP, Azarbarzin A, Wang H, Wellman A, Sands SA, Redline S.
Am J Respir Crit Care Med. 2020 Dec 07. PMID: 33285084
Granot-Hershkovitz E, Tarraf W, Kurniansyah N, Daviglus M, Isasi CR, Kaplan R, Lamar M, Perreira KM, Wassertheil-Smoller S, Stickel A, Thyagarajan B, Zeng D, Fornage M, DeCarli CS, González HM, Sofer T.
Alzheimers Dement. 2021 Mar. 17(3):466-474. PMID: 33155766
Sofer T, Guo N.
Genet Epidemiol. 2021 Feb. 45(1):115-127. PMID: 33094516
Tsivion-Visbord H, Kopel E, Feiglin A, Sofer T, Barzilay R, Ben-Zur T, Yaron O, Offen D, Levanon EY.
Nat Commun. 2020 10 16. 11(1):5236. PMID: 33067431
Zhao X, Qiao D, Yang C, Kasela S, Kim W, Ma Y, Shrine N, Batini C, Sofer T, Taliun SAG, Sakornsakolpat P, Balte PP, Prokopenko D, Yu B, Lange LA, Dupuis J, Cade BE, Lee J, Gharib SA, Daya M, Laurie CA, Ruczinski I, Cupples LA, Loehr LR, Bartz TM, Morrison AC, Psaty BM, Vasan RS, Wilson JG, Taylor KD, Durda P, Johnson WC, Cornell E, Guo X, Liu Y, Tracy RP, Ardlie KG, Aguet F, VanDenBerg DJ, Papanicolaou GJ, Rotter JI, Barnes KC, Jain D, Nickerson DA, Muzny DM, Metcalf GA, Doddapaneni H, Dugan-Perez S, Gupta N, Gabriel S, Rich SS, O'Connor GT, Redline S, Reed RM, Laurie CC, Daviglus ML, Preudhomme LK, Burkart KM, Kaplan RC, Wain LV, Tobin MD, London SJ, Lappalainen T, Oelsner EC, Abecasis GR, Silverman EK, Barr RG, Cho MH, Manichaikul A.
Nat Commun. 2020 10 14. 11(1):5182. PMID: 33057025
Tsivion-Visbord H, Perets N, Sofer T, Bikovski L, Goldshmit Y, Ruban A, Daniel O.
Transl Psychiatry. 2020 Oct 06. 10(1):341. PMID: 33024083