Professor

Xihong Lin

Professor of Biostatistics

Biostatistics

xlin@hsph.harvard.edu

Other Positions

Coordinating Director, Program in Quantitative Genomics

Biostatistics

Harvard T.H. Chan School of Public Health

Professor of Biostatistics and Statistics

Statistics

Faculty of Arts & Sciences

Professor of Statistics

Statistics

Faculty of Arts & Sciences

Links

Catalyst Profile

Bibliography

Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program.

Cade BE, Lee J, Sofer T, Wang H, Zhang M, Chen H, Gharib SA, Gottlieb DJ, Guo X, Lane JM, Liang J, Lin X, Mei H, Patel SR, Purcell SM, Saxena R, Shah NA, Evans DS, Hanis CL, Hillman DR, Mukherjee S, Palmer LJ, Stone KL, Tranah GJ, Abecasis GR, Boerwinkle EA, Correa A, Cupples LA, Kaplan RC, Nickerson DA, North KE, Psaty BM, Rotter JI, Rich SS, Tracy RP, Vasan RS, Wilson JG, Zhu X, Redline S.

Genome Med. 2021 Aug 26. 13(1):136. PMID: 34446064

The Association Between Inflammatory and Oxidative Stress Biomarkers and Plasma Metabolites in a Longitudinal Study of Healthy Male Welders.

Gao S, Quick C, Guasch-Ferre M, Zhuo Z, Hutchinson JM, Su L, Hu F, Lin X, Christiani D.

J Inflamm Res. 2021. 14:2825-2839. PMID: 34234508

Identifying US County-level characteristics associated with high COVID-19 burden.

Li D, Gaynor SM, Quick C, Chen JT, Stephenson BJK, Coull BA, Lin X.

BMC Public Health. 2021 05 28. 21(1):1007. PMID: 34049526

Integrative omics provide biological and clinical insights into acute respiratory distress syndrome.

Du M, Garcia JGN, Christie JD, Xin J, Cai G, Meyer NJ, Zhu Z, Yuan Q, Zhang Z, Su L, Shen S, Dong X, Li H, Hutchinson JN, Tejera P, Lin X, Wang M, Chen F, Christiani DC.

Intensive Care Med. 2021 07. 47(7):761-771. PMID: 34032881

Genome-wide association study of neck circumference identifies sex-specific loci independent of generalized adiposity.

Liu Y, Zhang X, Lee J, Smelser D, Cade B, Chen H, Zhou H, Kirchner HL, Lin X, Mukherjee S, Hillman D, Liu CT, Redline S, Sofer T.

Int J Obes (Lond). 2021 07. 45(7):1532-1541. PMID: 33907307

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.

Li X, Li Z, Zhou H, Gaynor SM, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Aslibekyan S, Ballantyne CM, Bielak LF, Blangero J, Boerwinkle E, Bowden DW, Broome JG, Conomos MP, Correa A, Cupples LA, Curran JE, Freedman BI, Guo X, Hindy G, Irvin MR, Kardia SLR, Kathiresan S, Khan AT, Kooperberg CL, Laurie CC, Liu XS, Mahaney MC, Manichaikul AW, Martin LW, Mathias RA, McGarvey ST, Mitchell BD, Montasser ME, Moore JE, Morrison AC, O'Connell JR, Palmer ND, Pampana A, Peralta JM, Peyser PA, Psaty BM, Redline S, Rice KM, Rich SS, Smith JA, Tiwari HK, Tsai MY, Vasan RS, Wang FF, Weeks DE, Weng Z, Wilson JG, Yanek LR, Neale BM, Sunyaev SR, Abecasis GR, Rotter JI, Willer CJ, Peloso GM, Natarajan P, Lin X.

Nat Genet. 2020 09. 52(9):969-983. PMID: 32839606

Analysis in case-control sequencing association studies with different sequencing depths.

Chen S, Lin X.

Biostatistics. 2020 07 01. 21(3):577-593. PMID: 30590456

Epigenomic analysis of 5-hydroxymethylcytosine (5hmC) reveals novel DNA methylation markers for lung cancers.

Wang Z, Du M, Yuan Q, Guo Y, Hutchinson JN, Su L, Zheng Y, Wang J, Mucci LA, Lin X, Hou L, Christiani DC.

Neoplasia. 2020 03. 22(3):154-161. PMID: 32062069

Operating characteristics of the rank-based inverse normal transformation for quantitative trait analysis in genome-wide association studies.

McCaw ZR, Lane JM, Saxena R, Redline S, Lin X.

Biometrics. 2020 12. 76(4):1262-1272. PMID: 31883270

Identification of differentially expressed gene sets using the Generalized Berk-Jones statistic.

Gaynor SM, Sun R, Lin X, Quackenbush J.

Bioinformatics. 2019 11 01. 35(22):4568-4576. PMID: 31062858

VIEW MORE PUBLICATIONS

News

Heavy smokers with non-small cell lung cancer could benefit from certain immunotherapies

Knowing the current and previous smoking habits of patients with metastatic non-small cell lung cancer (NSCLC) could allow clinicians to make better informed treatment decisions, according to new research led by Harvard T.H. Chan School of Public Health.…

Faculty News

Faculty awards and honors, appointments and promotions.

Three Harvard Chan School faculty named ‘changemakers of public health’

Mary Bassett, Bizu Gelaye, and Xihong Lin are among 50 alumni of the University of Washington School of Public Health who have been recognized as “changemakers” in the field of public health.

Biostats professor testifies before UK Parliament on COVID-19 response

Xihong Lin, professor of biostatistics at Harvard T.H. Chan School of Public Health, testified before the UK Parliament’s Science and Technology Committee in April. Lin’s testimony focused on lessons learned so far in the fight against COVID-19. Following…

New study sheds light on the spread and control of COVID-19 in Wuhan, China

A newly published analysis of 32,583 laboratory-confirmed COVID-19 cases in Wuhan, China sheds light on the epidemiological characteristics of the disease and shows that numerous non-pharmaceutical interventions, including social distancing, centralized isolation and quarantine, and a door-to-door universal…

view more news