Center for Biostatistics in AIDS Research (CBAR)

The Center for Biostatistics in AIDS Research (CBAR) is a Center at the Harvard School of Public Health whose mission is to foster and conduct statistical scientific activity in clinical trials and other public health research areas in HIV disease, to promote innovative strategies for medical interventions and study design, and to provide education and training relevant to statistical aspects of HIV disease research.

The largest project of CBAR is the Statistical and Data Analysis Center (SDAC) of the AIDS Clinical Trials Group (ACTG). The ACTG is a clinical cooperative group dedicated to AIDS research and is funded by the National Institutes of Allergies and Infectious Diseases (NIAID), a branch of the National Institutes of Health (NIH). Other CBAR projects include the Immune Response Corporation (IRC) clinical trials and the Neurologic AIDS Research Consortium (NARC), which funds neurological investigations for some ACTG investigators. Further information is available on the relationships among CBAR, SDAC, HSPH, FSTRF, and DFCI.

Since its creation in the Fall of 1995, the Center for Biostatistics in AIDS Research (CBAR) has been very active in research on new treatments for persons infected with HIV. With a staff of over 60 biostatisticians, we have been responsible for the design, monitoring, and analysis of most of the federally-funded clinical trials of HIV in the U.S. Because of the rapidly-changing standard of care of HIV due to improved virologic markers and new therapies, we also have played a key role in developing research strategy. In addition to our research on evaluation of therapies for HIV, a primary aim of CBAR has been to collaborate with governments and investigators from developing countries to assist in the design and analysis of vaccine and therapy trials of HIV, and to help to develop expertise and infrastructure in these countries so that they are in a better position to devise and implement programs for controlling the AIDS epidemic in their countries. These aims are reflected in our past accomplishments and goals for the coming year.

This page is maintained by Dr. Janet Andersen. To contact Dr. Anderson with suggestions, comments, and questions, please e-mail: andersen@sdac.harvard.edu.