Eric Tchetgen Tchetgen

Eric Tchetgen Tchetgen

Associate Professor of Biostatistics and Epidemiologic Methods

Department of Biostatistics
Department of Epidemiology

Department of Biostatistics

677 Huntington Avenue
Kresge, Room 822
Boston, Massachusetts 02115
Phone: 617.432.5970

Education

Ph.D., 2006, Harvard University
B.S., 1999, Yale University

Research

I am an associate professor with joint appointment in the departments of Epidemiology and Biostatistics at the Harvard School of Public Health.  My primary area of interest is in semi-parametric efficiency theory with application to causal inference, missing data problems, statistical genetics and mixed model theory.  In general, I work on the development of statistical and epidemiologic methods that make efficient use of the information in data collected by scientific investigators, while avoiding unnecessary assumptions about the underlying data generating mechanism.  Recently, my research with other collaborators has contributed new robust and efficient methods for the estimation of gene-environment statistical interactions in their effects on causing disease.

Publications

Tchetgen Tchetgen E and Robins J. The semi-parametric case-only estimator. Biometrics (2010) In Press

Cerdá M, Diez-Roux A, Tchetgen Tchetgen E, Gordon-Larsen P, Kiefe C.  Using marginal structural models to estimate the relationship between neighborhood poverty and alcohol use and misuse: the CARDIA study. Epidemiology (2010) In Press

Lipsitch M, Tchetgen Tchetgen E., Cohen T. The use of negative controls to detect confounding and other sources of error in experimental and observational science. Epidemiology (2010) In Press.

Robins J, Tchetgen Tchetgen E , Li L., van der Vaart, Semiparametric Minimax Rates. Electronic Journal of Statistics 2009,3, 1305-1321

Tchetgen Tchetgen E, Robins J, Rotnitzky A. On Doubly robust estimation of a semi-parametric odds ratio model. Biometrika (2009). In press

Tchetgen Tchetgen. A simple implementation of doubly robust estimation in logistic regression with covariates missing at random. Epidemiology 2009 ,vol 20, Issue 3 , pp 391-394

Vansteelandt S., VanderWeele T.J., Tchetgen Tchetgen E, Robins J.M., Multiply robust inference for statistical interactions. Journal of the American Statistical Association, December 2008, Vol. 103, No. 484, Theory and Methods

Tchetgen Tchetgen E, Li L, van der Vaart A., Robins J.  Minimax estimation of the integral of a power of a density. Statistics & Probability Letters. Volume 78,15 December 2008, Pages 3307-3311.

Tchetgen Tchetgen E J On Doubly and Multiple robustness in the analysis of randomized studies with informative dropout. An invited discussion of an article by Geert Molenberghs. Drug Information Journal 2009, vol 43 page 433-435.

Robins J, Li L, Tchetgen E. ,van der Vaart A. Quadratic semiparametric Von Mises Calculus. Metrika Volume 69, Numbers 2-3 , March 2009.

Robins J, Li L, Tchetgen E. ,van der Vaart A. Higher order influence functions and minimax estimation of nonlinear functionals. Probability and Statistics: Essays in Honor of David A. Freedman. Eds: Deborah Nolan and Terry Speed. 2008.

Harezlak J, Tchetgen E., Li, X. Variable selection in regression, prediction, screening, sparsity.  Modern statistical methods for high dimensional data. (In Press). 2008.

Tchetgen E, Coull B. A Diagnostic Test for the Mixing Distribution in a Generalized Linear Mixed Model, Biometrika 2006 93(4):1003-1010;

Tchetgen E, Lingling Li, van der Vaart A., Robins J. Robust Inference with Higher Order Influence Functions: Part I .Proceedings of the American Statistical Association , 2005, Minneapolis, Minnesota

Lingling Li, Tchetgen E, van der Vaart A, Robins J.  Robust Inference with Higher Order Influence Functions: Part II.  Proceedings of the American Statistical Association  2005, Minneapolis, Minnesota.

McDermott AY, Terrin N, Wanke C, Skinner S, Tchetgen E, Shevitz, AH. CD4+ cell count, viral load, and highly active antiretroviral therapy use are independent predictors of body composition alterations in HIV-infected Adults: a longitudinal study. Clinical Infectious Diseases. 2005 Dec 1:41(11):1662-70.

Tchetgen E, Kaplan EH, Friedland GH: The Public Health Consequences of Screening Patients for Adherence to HAART, Journal of AIDS 2000; 26:118-129.

Wilson IB, Tchetgen E, Spiegelman D. “Patterns of adherence with antiretroviral medications: an examination of between-medication differences”  Journal of AIDS 2001:Volume 28(3)1 pp 259-263

Forrester JE, Spiegelman D, Tchetgen E, Gorbach SL. Fat and lean body mass in HIV-associated weight loss. American Journal of Clinical Nutrition, Vol. 76, No. 6, 1428-1434, December 2002

Roubenoff R, Grinspoon S, Skolnik PR, Tchetgen E, Abad L, Spiegelman D et al. Role of cytokines and testosterone in regulating lean body mass and resting energy expenditure in HIV-infected men.  Am J Physiol Endocrinol Metab 2002; 283: E138-45

Tang AM, Forrester J, Spiegelman D, Knox TA, Tchetgen E, Gorbach SL. Weight Loss and Survival in HIV-Positive Patients in the Era of Highly Active Antiretroviral Therapy. Journal of AIDS 2002; 31: 230-6.