Center for Nanotechnology and Nanotoxicology

2019 Publications

  1. Zimmerman JF, Ardoña HAM, Pyrgiotakis G, Dong J, Moudgil B, Demokritou P, Parker KK. Scatter Enhanced Phase Contrast Microscopy for Discriminating Mechanisms of Active Nanoparticle Transport in Living Cells. Nano Letters. 2019;19(2):793–804. doi:10.1021/acs.nanolett.8b03903 [link]
  2. Singh D, Wohlleben W, Roche RDLT, White JC, Demokritou P. Thermal decomposition/incineration of nano-enabled coatings and effects of nanofiller/matrix properties and operational conditions on byproduct release dynamics: Potential environmental health implications. NanoImpact. 2019;13:44–55. doi:10.1016/j.impact.2018.12.003 [link]
  3. Zhang Z, Zhang R, Xiao H, Bhattacharya K, Bitounis D, Demokritou P, McClements DJ. Development of a standardized food model for studying the impact of food matrix effects on the gastrointestinal fate and toxicity of ingested nanomaterials. NanoImpact. 2019;13:13-25. [link]
  4. Vaze N, Pyrgiotakis G, Mena L, Baumann R, Demokritou A, Ericsson M, Zhang Y, Bello D, Eleftheriadou M, Demokritou P. A nano-carrier platform for the targeted delivery of nature-inspired antimicrobials using Engineered Water Nanostructures for food safety applications. Food Control. 2019 Feb;96:365-374. doi:1016/j.foodcont.2018.09.037 [link]
  5. Vaze N, Pyrgiotakis G, Mcdevitt J, Mena L, Melo A, Bedugnis A, Kobzik L, Eleftheriadou M, Demokritou P. Inactivation of common hospital acquired pathogens on surfaces and in air utilizing engineered water nanostructures (EWNS) based nano-sanitizers. Nanomedicine: Nanotechnology, Biology and Medicine. 2019 Feb;18:234–242. doi:10.1016/j.nano.2019.03.003 [link]
  6. Salari, M., Bitounis, D., Bhattacharya, K., Pyrgiotakis, G., Zhang, Z., Purington, E., Gramlich, W., Grondin, Y., Rogers, R., Bousfield, D., Demokritou, P. Development & characterization of fluorescently tagged nanocellulose for nanotoxicological studies. Sci.: Nano. 2019 April; (5):1516-26. doi:10.1039/C8EN01381K [link]
  7. Zhang Y, Demokritou P, Ryan DK, Bello D. Comprehensive assessment of short-lived ROS and H2O2 in laser printer emissions: Assessing the relative contribution of metal oxides and organic constituents. Environ Sci Technol. 2019 Jul 2; 53(13):7574-7583. doi: 10.1021/acs.est.8b05677 [link]
  8. Bitounis D, Pyrgiotakis G, Bousfield D, Demokritou P. Dispersion preparation, characterization, and dosimetric analysis of cellulose nano-fibrils and nano-crystals: Implications for cellular toxicological studies. NanoImpact. 2019 May 31. 15:100171. doi: 10.1016/j.impact.2019.100171. [link]
  9. Deloid G, Cao X, Molina R, Silva DI, Bhattacharya K, Ng KW, Loo SCJ, Brain J, Demokritou P. Toxicological effects of ingested nanocellulose in in vitro interstinal epithelium and in vivo rat models. Environmental Science:Nano. 2019 June 14; 6(7):2105-2115. doi: 10.1039/C9EN00184K [link]
  10. Pirela S, Bhattacharya K, Wang Y, Zhang Y, Wang G, Christophi CA, Godleski J, Thomas T, Qian Y, Orandle MS, Sisler JD, Bello D, Castranova V, Demokritou P. A 21-day sub-acute, whole-body inhalation exposure to printer-emitted engineered nanoparticles in rats: Exploring pulmonary and systemic effects. NanoImpact. 2019 July; 5:100176. doi: 10.1016/j.impact.2019.100176. [link]
  11. Sampathkumar K, Riyajan S, Tan C, Demokritou P, Chudapongse N, Loo S. Small-Intestine-Specific Delivery of Antidiabetic Extracts from Withania coagulans Using Polysaccharide-Based Enteric-Coated Nanoparticles. ACS omega. 2019 July 11; 4(7):12049-12057. doi: 10.1021/acsomega.9b00823 [link]
  12. Dong J, Carpinone PL, Pyrgiotakis G, Demokritou P, Moudgil BM. Synthesis of Precision Gold Nanoparticles Using Turkevich Method. KONA Powder and Particle Journal. 2020 January 10. 2020011. doi: 10.14356/kona.2020011 [link]
  13. Tsuda A, Donaghey TC, Konduru NV, Pyrgiotakis G, Van Winkle LS, Zhang Z, Edwards P, Bustamante J, Brain J, Demokritou P. Age-Dependent Translocation of Gold Nanoparticles Across the Air-Blood Barrier. ACS Nano. 2019 Aug 9. 2019 Sep 24;13(9):10095-10102. doi: 10.1021/acsnano.9b03019 [link]
  14. Cao X, DeLoid G, Bitounis D, De La Torre-Roche R, White JC, Zhang Z, Guan Ho C, Ng KW, Eitzer BD, Demokritou P. Co-exposure to the food additives SiO2 (E551) or TiO2 (E171) and the pesticide boscalid increases cytotoxicity and bioavailability of the pesticide in a tri-culture small intestinal epithelium model: potential health implications. Environmental Science: Nano. 2019 Aug 8; 6(9):2786-2800. doi: 10.1039/C9EN00676A [link]
  15. Eweje F, Ardoña HAM, Zimmerman JF, O’Connor BB, Ahn S, Grevesse T, Rivera KN, Bitounis D, Demokritou P, Parker KK. Quantifying the effects of engineered nanomaterials on endothelial cell architecture and vascular barrier integrity using a cell pair model. Nanoscale. 2019 September 24; 11: 17878-17893. [link]
  16. Bindraban P, Dimkpa C, White J, Franklin F, Melse-Boonstra A, Koele N, Pandey R, Rodenburg J, Senthilkumar K, Demokritou P, Schmidt S. Safeguarding human and planetary health demands a fertilizer sector transformation. Plants, People, Planet.
  17. Rubio L, Pyrgiotakis G, Beltran-Huarac J, Zhang Y, Gaurav J, Deloid G, Spyrogianni A, Sarosiek KA, Bello D, Demokritou P. Safer-by-design flame-sprayed silicon dioxide nanoparticles: the role of silanol content on ROS generation, surface activity and cytotoxicity. Particle & Fibre Toxicology. 2019 October 29; 16(40). Doi: 10.1186/s12989-019-0325-1 [link]
  18. Kornberg TG, Stueckle TA, Coyle J, Derk R, Demokritou P, Rojanasakul Y, Rojanasakul LW. Iron oxide nanoparticle-induced neoplastic-like cell transformation in vitro is reduced with protective amorphous silica coating. Chem Res Toxicol. 2019 Oct 28; 32(12):2382-2397. doi: 10.1021/acs.chemrestox.9b00118 [link]
  19. Huang R, Vaze N, Soorneedi A, Moore M, Xue Y, Bello D, Demokritou P. Inactivation of Hand Hygiene Related Pathogens Using Engineered Water Nanostructures. Sustainable Chem. Eng. 2019 Nov 10. 7(24):19761-19769. doi: 10.1021/acssuschemeng.9b05057 [link]
  20. Kim S, Gates B, Leonard BC, Gragg M, Pinkerton KE, Van Winkle L, Murphy CH, Pyrgiotakis G, Zhang Z, Demokritou P, Thomasy SM. Engineered metal oxide nanomaterials inhibit corneal epithelial wound healing in vitro and in vivo. NanoImpact. 2019 Dec 6. 17:100198. doi: 10.1016/j.impact.2019.100198 [link]
  21. Guo Z, Cao X, DeLoid G, Sampathkumar K, Ng KW, Loo SC, Demokritou, P. Physicochemical and morphological transformations of chitosan nanoparticles across the gastrointestinal tract and cellular toxicity in an in vitro model of the small intestinal epithelium. Journal of Agricultural and Food Chemistry. 2019 Dec 9.  68(1):358-368. doi: 10.1021/acs.jafc.9b05506 [link]
  22. Cao X, Zhang T, DeLoid GM, Gaffrey MJ, Weitz KK, Thrall BD, Qian W, Demokritou P. Evaluation of the cytotoxic and cellular proteome impacts of food-grade TiO2 (E171) using simulated gastrointestinal digestions and a tri-culture small intestinal epithelial model. 2019 Dec 6. 17:100202. doi: 10.1016/j.impact.2019.100202 [link]
  23. Guo NL, Poh TY, Pirela S, Farcas MT, Chotirmall SC, Tham WK, Adav SS, Ye Q, Wei Y, Shen S, Christiani DC, Ng KW, Thomas T, Qian Y, Demokritou P. Integrated transcriptomics, metabolomics, and lipidomics profiling in rat lung, blood, and serum for assessment of laser printer-emitted nanoparticle inhalation exposure-induced disease risks. International Journal of Molecular Sciences. 2019 Dec 12. 20:6348. [link]