TB superstrains
[ Fall 2008 ] Extensively drug-resistant tuberculosis is research focus Covering 200 square kilometers of arid scrubland in South Africa’s KwaZulu-Natal Province, the rural district of Tugela Ferry seems to swallow its inhabitants, its parched mountain ridges shutting out the…
Dual role of molecule in mice may open new avenue to cholesterol reduction
For Immediate Release: Thursday, June 12, 2008 Boston, MA -- Researchers have discovered an unknown regulator of fat and cholesterol production in the liver of mice, a significant finding that could lead to new therapies for lowering unhealthy…
Hope for a needle-free TB vaccine
[ Spring 2008 ] New "dry-spray" technology passes muster in guinea pigs Aiming to make immunization safer and more cost-effective for the developing world, Harvard School of Public Health Dean Barry R. Bloom and two bioengineers at Harvard, David Edwards and doctoral…
Inhaled tuberculosis vaccine more effective than traditional shot in study using experimental animals
For Immediate Release: March 12, 2008 Boston, MA -- A novel aerosol version of the most common tuberculosis (TB) vaccine, administered directly to the lungs as an oral mist, offers significantly better protection against the disease in experimental…
Inflammatory bowel disease: Trouble at the border
In the healthy colon, or bowel, of both mice and humans, a thin lining protects the intestinal wall from bacteria. There, immune system dendritic cells in the wall sample bacteria that live within the bowel, vigilant against unwelcome…
Bacteria without borders
[ Winter 2008 ] Scientists trace inflammatory ulcerative colitis to failure of immune system “peacekeeper” A delicate barrier is all that stands between billions of foreign bacteria living in the large intestine, or colon, and the misery of ulcerative colitis.…
