A molecular dive into how cells sense nutrients
Krystle Kalafut, PhD ’24, studies the liver’s response to insulin, revealing potential mechanisms involved in obesity and diabetes.
Department of Molecular Metabolism celebrates 20th anniversary
Over 100 current and former members of Harvard T.H. Chan School of Public Health’s Department of Molecular Metabolism gathered on September 7 to celebrate the 20th anniversary of the department’s founding, to reflect on the successes of the…
Unlocking cellular secrets to better treat diseases
Sophie Lockwood, PhD ’23, uncovered a complex biological mechanism that could potentially help in drug development.
The Cancer Miracle Isn't a Cure. It's Prevention.
We cannot treat our way out of the rising trend in cancer cases. The only solution is a full-scale defense, so that nobody suffers the disease in the first place.
A new route to control cell metabolism and growth
March 26, 2019—In a new Science paper, Brendan Manning, professor of genetics and complex diseases, and colleagues reveal how a previously understudied enzyme may help fuel the metabolism of cancer cells and contribute to the development of other…
Targeting tumor metabolic vulnerabilities
December 8, 2017 – A research team at Harvard T.H. Chan School of Public Health has identified a key metabolic vulnerability in some types of tumor cells and discovered a way to exploit it by harnessing well-known immunosuppressant…
Xihong Lin, Brendan Manning, Shuji Ogino receive prestigious NCI awards
October 20, 2015 — It was announced this week that two faculty members from Harvard T.H. Chan School of Public Health—Xihong Lin and Brendan Manning—received prestigious National Cancer Institute Outstanding Investigator Awards (OIA). These multimillion-dollar seven-year awards, providing…
New insights into mechanism behind tuberous sclerosis complex tumors
Findings by Harvard School of Public Health’s Brendan Manning, professor of genetics and complex diseases, are providing new insights into tuberous sclerosis complex (TSC) — a rare genetic disease that causes the widespread growth of benign tumors —…
HSPH researchers identify key mechanism in cellular growth process
March 13, 2013 — A new study by Harvard School of Public Health (HSPH) researchers is the first to identify the primary mechanism controlling a metabolic process essential for cell growth and proliferation. This pathway is centered around…
HSPH faculty members honored
November 30, 2012 -- Brendan Manning, associate professor of genetics and complex diseases, received a 2012 Senior Scholar in Aging Award from The Ellison Medical Foundation for his research on determining the genetic and metabolic relationship between the major longevity…
