David J. Hunter
Professor

David J. Hunter

Vincent L. Gregory Professor of Cancer Prevention, Emeritus

Epidemiology

dhunter@hsph.harvard.edu

Other Positions

Professor of Medicine, Emeritus

Emeritus

Brigham and Women's Hospital


Overview

David Hunter's principal research interests are the etiology of cancer in women, particularly breast, ovarian, and skin cancer. He is an investigator on the Nurses' Health Study, a long-running cohort of 121,000 US women, and is project director for the Nurses' Health Study II, a newer cohort of 116,000 women. He also analyzes inherited susceptibility to cancer and other chronic diseases using molecular techniques and studying molecular markers of environmental exposures. This work is based in subcohorts of the Nurses Health Study and the Health Professionals Follow-up Study of approximately 33,000 women and 18,000 men who have given a blood sample that can be used for DNA analysis. Dr. Hunter supervises laboratories at the Harvard School of Public Health in which gene sequence information from these samples is obtained. He is Co-Chair of the NCI Breast and Prostate Cancer Cohort Consortium. He collaborates with investigators in Tanzania to understand the relationship of nutritional status to progression of HIV disease and perinatal transmission. Professor Hunter was the Director of the Harvard Center for Cancer Prevention from 1997-2003, and is now Director of the Program in Molecular and Genetic Epidemiology, Harvard School of Public Health.


Bibliography

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.

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Nat Genet. 2021 Jan. 53(1):65-75. PMID: 33398198

Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer.

Kho PF, Amant F, Annibali D, Ashton K, Attia J, Auer PL, Beckmann MW, Black A, Brinton L, Buchanan DD, Chanock SJ, Chen C, Chen MM, Cheng THT, Cook LS, Crous-Bous M, Czene K, De Vivo I, Dennis J, Dörk T, Dowdy SC, Dunning AM, Dürst M, Easton DF, Ekici AB, Fasching PA, Fridley BL, Friedenreich CM, García-Closas M, Gaudet MM, Giles GG, Goode EL, Gorman M, Haiman CA, Hall P, Hankinson SE, Hein A, Hillemanns P, Hodgson S, Hoivik EA, Holliday EG, Hunter DJ, Jones A, Kraft P, Krakstad C, Lambrechts D, Le Marchand L, Liang X, Lindblom A, Lissowska J, Long J, Lu L, Magliocco AM, Martin L, McEvoy M, Milne RL, Mints M, Nassir R, Otton G, Palles C, Pooler L, Proietto T, Rebbeck TR, Renner SP, Risch HA, Rübner M, Runnebaum I, Sacerdote C, Sarto GE, Schumacher F, Scott RJ, Setiawan VW, Shah M, Sheng X, Shu XO, Southey MC, Tham E, Tomlinson I, Trovik J, Turman C, Tyrer JP, Van Den Berg D, Wang Z, Wentzensen N, Xia L, Xiang YB, Yang HP, Yu H, Zheng W, Webb PM, Thompson DJ, Spurdle AB, Glubb DM, O'Mara TA.

Int J Cancer. 2021 Jan 15. 148(2):307-319. PMID: 32851660


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